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Results for "

Actin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Arp2/3 Complex (26) Acyltransferase (1) Akt (4) Aldehyde Dehydrogenase (ALDH) (1) Amino acid Transporter (1) Aminoacyl-tRNA Synthetase (1) AMPK (1) Androgen Receptor (1) Antibiotic (3) Apoptosis (14) ATP Synthase (2) Autophagy (5) Bacterial (6) Bcl-2 Family (1) Biochemical Assay Reagents (6) Cadherin (1) Calcium Channel (3) CaMK (4) Carbonic Anhydrase (1) Caspase (5) Cathepsin (2) CCR (1) CDK (3) Checkpoint Kinase (Chk) (1) Choline Kinase (1) Collagen (1) CXCR (8) Disulfidptosis (3) DNA Methyltransferase (1) DNA/RNA Synthesis (2) Drug Derivative (4) Drug Isomer (1) Drug Metabolite (4) Dynamin (1) EGFR (3) Endogenous Metabolite (15) Endothelin Receptor (1) Epigenetic Reader Domain (3) Epoxide Hydrolase (2) ERK (4) Exosomes (1) FAK (2) Fluorescent Dye (9) Fungal (7) Galectin (1) GLUT (5) HBV (2) HDAC (1) Histamine Receptor (6) Histone Methyltransferase (1) HIV (2) HIV Integrase (1) HIV Protease (1) HSP (1) IFNAR (1) Integrin (3) Interleukin Related (2) Isotope-Labeled Compounds (12) LIM Kinase (LIMK) (4) Liposome (1) mAChR (1) MEK (2) Microtubule/Tubulin (8) Mitochondrial Metabolism (1) MMP (3) mRNA (1) mTOR (1) Myosin (9) nAChR (4) NF-κB (7) Notch (1) Nuclear Factor of activated T Cells (NFAT) (1) Oxidative Phosphorylation (1) P2X Receptor (1) P2Y Receptor (1) p38 MAPK (4) PAK (1) Parasite (4) PERK (1) Phosphodiesterase (PDE) (1) Phosphorylase (1) PI3K (2) PKA (1) PPAR (1) Prostaglandin Receptor (2) PROTACs (1) Proteasome (1) Raf (2) RANKL/RANK (2) Ras (5) Reactive Oxygen Species (ROS) (4) Reference Standards (10) ROCK (8) Sodium Channel (1) Src (2) STAT (3) Survivin (2) TGF-beta/Smad (4) TGF-β Receptor (2) TNF Receptor (1) Topoisomerase (1) Wee1 (1) YAP (1) β-catenin (5)
By Research Areas:	Cancer (74) Cardiovascular Disease (15) Endocrinology (4) Infection (22) Inflammation/Immunology (40) Metabolic Disease (21) Neurological Disease (25)
Click Chemistry:	Azide (1)
Oligonucleotides:	Nucleotide Analogs (1) mRNA (1) Phospholipids (2)

171

Inhibitors & Agonists

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Biochemical Assay Reagents

Peptides

MCE Kits

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Isotope-Labeled Compounds

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Cytochalasin B 40+ Cited Publications Phomin	Arp2/3 Complex	Cancer
Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of *actin* filaments, disrupting the formation of actin polymers, with K_d value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration.

CK-666 20+ Cited Publications	Arp2/3 Complex HIV	Infection Cancer
CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC₅₀=12 μM). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation .

Narciclasine 20+ Cited Publications Lycoricidinol	ROCK	Cancer
Narciclasine is a plant growth modulator. Narciclasine modulates the Rho/Rho kinase/LIM kinase/cofilin signaling pathway, greatly increasing GTPase RhoA activity as well as inducing actin stress fiber formation in a RhoA-dependent manner.

Jasplakinolide 5+ Cited Publications	Arp2/3 Complex Fungal	Infection Cancer
Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a K_d of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity .

Latrunculin B 5+ Cited Publications	Fungal	Infection
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .

Latrunculin A 10+ Cited Publications LAT-A	Arp2/3 Complex	Cancer
Latrunculin A (LAT-A), found in the red sea sponge Latrunculia magnifica, is a *G-actin* polymerization** inhibitor. Latrunculin A binds to actin monomers and inhibits polymerization of actin with K_ds of 0.1, 0.4, 4.7 μM and 0.19 μM for ATP-actin, ADP-Pi-actin, ADP-actin and G-actin, respectively. Latrunculin A has effective anti-metastatic properties for cancer research. Latrunculin A blocks cell migration .

Phalloidin Maximum Cited Publications 23 Publications Verification	Fluorescent Dye	Others
Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome .

SMIFH2 5+ Cited Publications	Arp2/3 Complex	Cancer
SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton .

TB500 1 Publications Verification	Drug Derivative Akt P2X Receptor	Inflammation/Immunology
TB500 is a synthetic version of an active region of thymosin β₄. TB500 exhibits anti-fibrotic and wound healing activities by inhibiting the Akt signaling pathway and binding to actin. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation .

4-Hydroxyacetophenone 1 Publications Verification P-hydroxyacetophenone	HBV Myosin	Infection Inflammation/Immunology Cancer
4-Hydroxyacetophenone (P-hydroxyacetophenone) is a major hepatoprotective and choleretic compound found in Artemisia and Illicium plants, exhibiting antiviral and anti-inflammatory effects against hepatitis B virus. Additionally, 4-Hydroxyacetophenone inhibits cancer cell adhesion, invasion, and migration by remodeling actin. 4-Hydroxyacetophenone holds promise for research in the fields of inflammatory diseases and cancer .

Resolvin D1 1 Publications Verification RvD1	Endogenous Metabolite	Inflammation/Immunology
Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α–mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages .

3-Methyl-L-histidine	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
3-Methyl-L-histidine is an endogenous amino acid that can be found in actin and myosin .

CK-869 3 Publications Verification	Arp2/3 Complex	Cancer
CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor, with an IC₅₀ of 7 μM.

Tetrahydrocortisol	Microtubule/Tubulin	Neurological Disease Cancer
Tetrahydrocortisol is a cortisol metabolite that inhibits dexamethasone-induced formation of cross-linked actin networks. Tetrahydrocortisol can be used in the research of primary open-angle glaucoma, glucocorticoid-induced ocular hypertension, Lewis lung carcinoma, and EMT-6 mouse breast cancer .

Cytochalasin D Maximum Cited Publications 91 Publications Verification Zygosporin A; NSC 209835	Exosomes Arp2/3 Complex Antibiotic YAP	Infection Cancer
Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin–cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap .

EG-011	Arp2/3 Complex	Cancer
EG-011 is the first-in-class and potent Wiskott-Aldrich syndrome protein (WASP) activator. EG-011 activates the auto-inhibited form of WASP with strong actin polymerization. EG-011 has selective anti-tumor activity in lymphomas .

BTS 3 Publications Verification N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine	Myosin	Others
BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC₅₀s of ~5 µM for actin- and Ca ²⁺-stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers .

Cucurbitacin IIa 1 Publications Verification Hemslecin A	Survivin Apoptosis EGFR Caspase p38 MAPK Autophagy MEK Raf ERK STAT CaMK	Inflammation/Immunology Cancer
Cucurbitacin IIa (Hemslecin A) is an orally active, blood-brain barrier-permeable EGFR inhibitor with an IC₅₀ of 1.455 nM against human EGFR. Cucurbitacin IIa induces caspase-3-dependent apoptosis, downregulates survivin expression, enhances autophagy levels, disrupts the actin cytoskeleton via actin aggregation, arrests the cell cycle at the G2/M phase, and exerts anti-inflammatory activity by inhibiting the EGFR-MAPK signaling pathway. Cucurbitacin IIa can be used in the research of inflammation-related diseases, depression, and cancers such as non-small cell lung cancer .

Benproperine phosphate 2 Publications Verification	Arp2/3 Complex	Inflammation/Immunology Cancer
Benproperine phosphate is an orally active, potent actin-related protein 2/3 complex subunit 2 (ARPC2) inhibitor. Benproperine phosphate attenuates the actin polymerization rate of action polymerization nucleation by impairing Arp2/3 function. Benproperine phosphate has the potential for a cough suppressant and suppresses cancer cell migration and tumor metastasis .

Para-aminoblebbistatin	Myosin	Cardiovascular Disease Neurological Disease
Para-aminoblebbistatin is the inhibitor for myosin II. Para-aminoblebbistatin inhibits the ATPase activity of myosin II, thereby blocking the formation and contraction of the actin-myosin network. Para-aminoblebbistatin is a non-fluorescent and photostable Blebbistatin (HY-13813) derivative .

DCVJ 9-(2,2-Dicyanovinyl)julolidine	Fluorescent Dye	Others
DCVJ (9-(2,2-Dicyanovinyl)julolidine), a molecular rotor and unique fluorescent dye, binds to tubulin and actin, and increases its fluorescence intensity drastically upon polymerization. DCVJ also binds to phospholipid bilayers and increases its fluorescence intensity. DCVJ can detect the kinetic process of degranulation of mast cells (Absorption/emission=489/505 nm) .

CCG-222740 1 Publications Verification	Ras ROCK	Cancer
CCG-222740 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor . CCG-222740 is also a potent inhibitor of alpha-smooth muscle actin protein expression. CCG-222740 effectively reduces fibrosis in skin and blocks melanoma metastasis .

MT-110 BPN-0027490	Myosin	Neurological Disease
MT-110 (BPN-0027490) is a non-muscle myosin NMIIB-selective inhibitor with high brain penetration and favorable safety profile. MT-110 specifically disrupts NMIIB-dependent actin dynamics in dendritic spines, while it exerts no significant adverse effects on cardiac myosin II and cardiac functions (such as cardiac output and heart rate) at tested concentrations. A single administration of MT-110 produces long-lasting (sustained for several weeks) blockade of methamphetamine motivation associated with environmental cues. MT-110 exhibits extremely high specificity, with no interference with cocaine motivation, hippocampus-dependent memory, fear memory, or locomotor and anxiety-like behaviors. MT-110 serves as a valuable tool compound for investigating the mechanisms of methamphetamine use disorder .

LHVS 3 Publications Verification	Cathepsin Parasite	Infection Neurological Disease
LHVS is a potent, non-selective, irreversible, cell-permeable cysteine protease and cathepsin inhibitor. LHVS decreases actin ring formation. LHVS inhibits T. gondii invasion with an IC₅₀ of 10 μM .

CK-636 4 Publications Verification CK-0944636	Arp2/3 Complex	Inflammation/Immunology Cancer
CK-636 is a cell permeable inhibitor of Arp2/3 complex, that could inhibit actin polymerization, with IC₅₀ values of 4 μM, 24 μM and 32 μM for human, fission yeast and bovine, respectively. CK636 blocks cell migration.

Phallacidin	Arp2/3 Complex	Others
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a K_d of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .

Aminopurvalanol A 1 Publications Verification	CDK Apoptosis	Cancer
Aminopurvalanol A is a potent, selective, and cell permeable inhibitor of Cyclins/Cdk complexes. Aminopurvalanol A preferentially targets the G2/M-phase transition inhibiting cancer cell differentiation. Aminopurvalanol A causes the inhibition of sperm fertilizing ability via the inhibition of physiological capacitation-dependent actin polymerization .

Hydroxyacetone	Mitochondrial Metabolism Reactive Oxygen Species (ROS) Arp2/3 Complex Apoptosis	Inflammation/Immunology
Hydroxyacetone is a toxic compound. Hydroxyacetone can be isolated from e-cigarette aerosols. Hydroxyacetone reduces the activity of cellular Mitochondrial reductase (with an IC₅₀ of 5.53 mg/mL for mitochondrial reductase in BEAS-2B cells) and increases ROS levels. Hydroxyacetone induces mitochondrial stress and oxidative damage. Hydroxyacetone induces destabilization of *F-actin. At high concentrations, Hydroxyacetone promotes cell rounding and Apoptotic* body formation. Hydroxyacetone exerts toxic effects on cells including airway epithelial cells and possesses respiratory toxicity potential .\n

2-Bromoacetamide	Aldehyde Dehydrogenase (ALDH) Microtubule/Tubulin	Metabolic Disease
2-Bromoacetamide is a disinfection byproduct. 2-Bromoacetamide can inactivate liver alcohol dehydrogenase and interfere with microtubule and *actin* cytoskeletal function. 2-Bromoacetamide is a potent developmental toxicant in animals .

Bis-T-23 AG1717	Dynamin HIV Integrase	Infection Metabolic Disease Inflammation/Immunology
Bis-T-23 (AG1717), tyrphostin derivative, is an HIV-I integrase inhibitor. Bis-T-23 can promote actin-dependent dynamin oligomerization. Bis-T-23 can be used for the research of HIV and chronic kidney diseases (CKD) .

Chaetoglobosin A	Apoptosis Endogenous Metabolite Fungal Parasite Arp2/3 Complex	Infection Cancer
Chaetoglobosin A is a secondary metabolite and nematicide. Chaetoglobosin A is produced by Penicillium aquamarinium. Chaetoglobosin A targets Filamentous actin in cells, thereby inducing cell cycle arrest, and inhibiting membrane ruffle formation and cell migration. Chaetoglobosin A preferentially induces Apoptosis in chronic lymphocytic leukemia cells. Chaetoglobosin A induces dose- and time-dependent death in J2 larvae of the southern root-knot nematode (Meloidogyne incognita). Chaetoglobosin A can be used in studies related to root-knot nematode disease and chronic lymphocytic leukemia .

3-(4-Pyridyl)indole Rockout; 3-(4-Pyridinyl)-1H-indole; Rho Kinase Inhibitor III, Rockout	ROCK	Inflammation/Immunology
3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC₅₀ of 25 μM. 3-(4-Pyridyl)indole can inhibit blebbing and cause dissolution of actin stress fibers in a wound healing assay .

Nelutroctiv CK-136	Calcium Channel	Cardiovascular Disease
Nelutroctiv (CK-136) is an orally active and selective cardiac troponin activator. Nelutroctiv activates cardiac sarcomeres by enhancing the sensitivity of troponin to calcium ions and promoting the interaction between actin and myosin. Nelutroctiv enhances cardiac contractility. Nelutroctiv can be used in the researches for cardiovascular diseases with impaired cardiac contractile function .

Swinholide A	Fungal	Infection
Swinholide A is the *actin*-binding marine polyketide and dimerizes actin with the K_d of ~ 50 nM . Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filaments. Swinholide A disrupts the actin cytoskeleton of cells.Antifungal activity .

Dihydrocytochalasin B	Arp2/3 Complex DNA/RNA Synthesis Calcium Channel	Inflammation/Immunology
Dihydrocytochalasin B is an *Actin* disruptor. Dihydrocytochalasin B disrupts actin microfilament bundles, inhibits actin polymerization, and alters intracellular actin cytoskeletal structures. Dihydrocytochalasin B blocks the initiation of DNA synthesis. Dihydrocytochalasin B inhibits Calcium transport. Dihydrocytochalasin B inhibits cytokinesis and alters cell morphology. Dihydrocytochalasin B can be used in studies related to rickets .

Fequesetide	Arp2/3 Complex	Inflammation/Immunology
Fequesetide, a peptide segment, is the active site within the protein thymosin β₄ responsible for actin binding, cell migration and wound healing .

2,3-Bis(3-indolylmethyl)indole	RANKL/RANK	Others
2,3-Bis(3-indolylmethyl)indole significantly suppresses RANKL-induced osteoclast formation, actin ring formation, and bone resorption in a concentration-dependent manner.

3-Methyl-L-histidine-d3 1 Publications Verification	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
3-Methyl-L-histidine-d₃ is the deuterium labeled 3-Methyl-L-histidine. 3-Methyl-L-histidine is an endogenous amino acid that can be found in actin and myosin .

Cytochalasin A	HIV Protease Fungal	Infection
Cytochalasin A is a cell-permeable fungal toxin that is an oxidized derivative of cytochalasin B. Cytochalasin A is an inhibitor of HIV-1 protease (IC₅₀=3 μM) and inhibits actin polymerization and interferes with microtubule assembly by reacting with sulfhydryl groups. Antibiotic and fungicidal activitives .

MLS000532223	Ras	Cancer
MLS000532223 is a high affinity, selective inhibitor of Rho family GTPases, with EC₅₀ values ranging from 16 μM to 120 μM. MLS000532223 prevents GTP binding to several GTPases .

Myosin V-IN-1	Myosin	Neurological Disease
Myosin V-IN-1 (compound 8) is a potent and selective Myosin V inhibitor, with a K_i of 6 μM. Myosin V-IN-1 shows acute inhibition of myosin V. Myosin V-IN-1 slows the actin-activated myosin V ATPase by specifically inhibiting ADP release from the actomyosin complex .

Centaureidin	IFNAR ROCK	Inflammation/Immunology Cancer
Centaureidin is an orally active IFN-promoter that can be isolated from Bidens pilosa with an EC₅₀ of 0.9 μg/mL. Centaureidin activates the Rho signal pathway, leading to actin and tubulin disassembly, and resulting in dendrite retraction and stress fiber formation in melanocytes. Centaureidin shows high tumor cell growth inhibitory activities. Centaureidin significantly inhibits paw edema in mice ^{[1][2][3][4][5]}.

Cytochalasin E	Autophagy	Cancer
Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation .

Cucurbitacin F	Bacterial Caspase Apoptosis	Infection
Cucurbitacin F is a tetracyclic protostane-type triterpenoid with low toxicity, antibacterial and anti-inflammatory activities, and is also a related compound of Cucurbitacin B (HY-N0416). Cucurbitacin F widely exists in plants such as Cucurbitaceae plants, Quisqualis indica and Sorbaria sorbifolia. Cucurbitacin F acts as an actin aggregator and reduces cell viability in a dose-dependent manner. Cucurbitacin F induces apoptosis by triggering G2/M phase cell cycle arrest and activating the caspase-3-dependent apoptosis .

YH-306	FAK Src PI3K MMP Apoptosis	Cancer
YH-306 is an antitumor agent. YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. YH-306 significantly inhibits the migration and invasion of colorectal cancer cells. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9. YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization .

TR-100	Arp2/3 Complex	Metabolic Disease Cancer
TR-100 is a small molecule inhibitor of tumor-associated troponin (Tpm). TR-100 affects the interaction of Tpm3.1 with actin filaments by binding to the C-terminal of Tpm3.1, thereby affecting the stability and function of the actin filaments. This mechanism of action allows TR-100 to specifically affect actin filaments in cancer cells without compromising heart muscle function. TR-100 can be used to study the role of Tpm3.1 in cancer cell proliferation and survival and the effects of Tpm3.1 on insulin-stimulated glucose uptake and insulin secretion .

Cat. No.	Product Name

HY-L060

Cytoskeleton Compound Library

2,148 compounds

The cytoskeleton is responsible for contraction, cell motility, movement of organelles and vesicles through the cytoplasm, cytokinesis, intracellular signal transduction, and many other functions that are essential for cellular homeostasis and survival. It accomplishes these tasks through three basic structures: F-actin, microtubules, and intermediate filaments (IFs). The cytoskeleton is a dynamic structure where the three major filaments and tubules are under the influence of proteins that regulate their length, state of polymerization, and level of cross-linking. Since cytoskeleton is involved in virtually all cellular processes, cytoskeletal protein aberrations are the underlying reason for many pathological phenotypes, including several cardiovascular disease syndromes, neurodegeneration, cancer, liver cirrhosis, pulmonary fibrosis, and blistering skin diseases.

MCE designs a unique collection of 2,148 cytoskeleton-related compounds mainly focusing on the key targets in the cytoskeleton signal pathway and can be used in the research of cytoskeleton signal pathway and related diseases.

Cat. No.	Product Name	Type

HY-D0098

Fluorescein-5-maleimide

5 Publications Verification

N-(5-Fluoresceinyl)maleimide

Fluorescent Dye

Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .

HY-D1346

610CP	Fluorescent Dye
610CP is a new type of actin labeling dye. It dissolves in organic solvents. In DMSO the 610CP excitation/emission wavelength is between 609 and 634 nm. 610CP is a fluorescent dye that penetrates living cells. Upon cell entry, 610CP binds to Bromo-des-methyl-Jasplakinolide Therefore, 610CP dye can be used to stain actin fluorescence images with low background and high resolution.

HY-D2949

SNAP-549	Fluorescent Dye
SNAP-549 is a DY-549P1-labeled SNAP tag fluorescent probe, specifically designed for single-molecule imaging and dynamic tracking of proteins in living cells. SNAP-549 only labels SNAP-tag fusion proteins, with low background signals and forming irreversible connections, making it suitable for long-term observation .

HY-D1525

N-(7-Nitrobenzofurazan-4-yl)phallacidin	Fluorescent Dye
N-(7-Nitrobenzofurazan-4-yl)phallacidin is a fluorochrome. N-(7-Nitrobenzofurazan-4-yl)phallacidin can be used visualizing probe for actin .

HY-D3306

Tubulin-RedTracker	Fluorescent Dye
Tubulin-RedTracker is a paclitaxel-derived fluorescent microtubule-binding probe. Tubulin-RedTracker induces F-actin cytoskeleton defects at relatively high concentrations. (Ex/Em = 652/669) .

HY-D3153

PbQ

Fluorescent Dye

PbQ is a tubulin inhibitor (with an IC₅₀ of 5 μM against goat tubulin) and a fluorescent probe for cuprous ions Cu (I). PbQ can penetrate the membrane of peripheral blood mononuclear cells, form a stable 1:1 complex with Cu ⁺ ions, and exhibits low toxicity and good biocompatibility toward macrophage cell lines. In addition, PbQ promotes tubulin degradation and disrupts the microtubule network in lung epithelial cells without affecting actin. PbQ also possesses genotoxicity by forming DNA base adducts, and it can activate caspase-3 and apoptosis-related genes, induce loss of mitochondrial membrane potential, and trigger cell apoptosis. PbQ can be used in studies related to chronic obstructive pulmonary disease .

HY-DY1088

Fluorescein-5-maleimide (solution)

N-(5-Fluoresceinyl)maleimide (solution)

Fluorescent Dye

Fluorescein-5-maleimide (solution) (N-(5-Fluoresceinyl)maleimide (solution)) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .

Solvent and concentration: DMSO: 10 mM

Cat. No.	Product Name	Type

HY-132142

5-Propargylamino-dCTP	Biochemical Assay Reagents
5-Propargylamino-dCTP is a sustrate for DNA polymerases. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-Y1890B

Cremophor EL-10

Biochemical Assay Reagents

Cremophor EL-10 is a nonionic polyoxyethylene castor oil surfactant with multiple functions including organic solubilizer, mixed zinc anode corrosion inhibitor and dendrite growth inhibitor. By forming a physical barrier to block electrolyte contact and constructing oriented hydration channels to reduce the desolvation energy barrier of Zn ²⁺, Cremophor EL-10 achieves a corrosion inhibition efficiency of over 99%. Cremophor EL-10 exerts no significant effects on the mitochondrial activity and cell viability of epithelial cells, making it suitable for in vitro drug delivery and biopharmaceutical research at concentrations ≤10% v/v. However, Cremophor EL-10 may induce sustained non-endothelium-dependent contraction in rat aortic rings and exert concentration-dependent inhibitory effects on acetylcholine-induced endothelium-dependent relaxation responses .

HY-157651

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1'-myo-inositol-3',4'-bisphosphate ammonium	Biochemical Assay Reagents
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4'-bisphosphate) ammonium regulates the activity of the actin network associated with endocytic structures .

HY-157699

1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium

Biochemical Assay Reagents

1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium is a membrane-bound signaling molecule with intracellular activity in regulating membrane trafficking and signal transduction. 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium can be used in the preparation of liposomes to enhance the efficiency of compound delivery. 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium can also act as a coordinator of the actin cytoskeleton and participate in the regulation of cell morphology and motility.

HY-NP208

Myelin Basic Protein (Porcine)	Biochemical Assay Reagents
Myelin Basic Protein (Porcine), the second most abundant protein in central nervous system myelin, is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin. Myelin Basic Protein (Porcine) mediates interactions with actin and tubulin and effect of post-translational modifications .

Cat. No.	Product Name	Target	Research Area

HY-P0027

Jasplakinolide 5+ Cited Publications	Arp2/3 Complex Fungal	Infection Cancer
Jasplakinolide is a potent actin polymerization inducer and stabilizes pre-existing actin filaments. Jasplakinolide binds to F-actin competitively with phalloidin with a K_d of 15 nM. Jasplakinolide, a naturally occurring cyclic peptide from the marine sponge, has both fungicidal and anti-cancer activity .

HY-P0028

Phalloidin Maximum Cited Publications 23 Publications Verification	Fluorescent Dye	Others
Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome .

HY-P0170

TB500 1 Publications Verification	Drug Derivative Akt P2X Receptor	Inflammation/Immunology
TB500 is a synthetic version of an active region of thymosin β₄. TB500 exhibits anti-fibrotic and wound healing activities by inhibiting the Akt signaling pathway and binding to actin. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation .

HY-P0204A

Endothelin-3, human, mouse, rabbit, rat TFA 1 Publications Verification Endothelin 3 (Rat,Human) TFA	Endothelin Receptor Integrin	Neurological Disease
Endothelin-3, human, mouse, rabbit, rat TFA (Endothelin 3 (Rat,Human) TFA) is an adhesion stimulant. Endothelin-3, human, mouse, rabbit, rat TFA stimulates the adhesion of enteric neural crest cells to various ECM components. Endothelin-3, human, mouse, rabbit, rat TFA plays an important role in the maintenance and self-renewal of intestinal progenitor cells, participates in the migration of enteric neural crest cells, and helps maintain a suitable environment for the colonization of enteric neural crest cells. Endothelin-3, human, mouse, rabbit, rat TFA acts synergistically with the β1-integrin signaling pathway during enteric nervous system development. Endothelin-3, human, mouse, rabbit, rat TFA can be used in studies related to distal aganglionosis .

HY-P2031

Phallacidin	Arp2/3 Complex	Others
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a K_d of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .

HY-P1116

PBP10 1 Publications Verification	Bacterial Reactive Oxygen Species (ROS) Interleukin Related	Infection Inflammation/Immunology
PBP10 is a decapeptide. PBP10 selectively binds to lipoteichoic acid (LTA), lipopolysaccharide (LPS) and phosphatidylinositol-4,5-bisphosphate (PIP₂). PBP10 penetrates cell membranes and possesses bactericidal, anti-inflammatory, cell motility-inhibiting and actin assembly-regulating activities. PBP10 is applicable to relevant research on bacterial infections, microbe-induced inflammation, skin and soft tissue infections, as well as sepsis .

HY-P2463

Fequesetide	Arp2/3 Complex	Inflammation/Immunology
Fequesetide, a peptide segment, is the active site within the protein thymosin β₄ responsible for actin binding, cell migration and wound healing .

HY-P1116A

PBP10 TFA 1 Publications Verification	Bacterial	Infection Inflammation/Immunology
PBP10 TFA is a decapeptide. PBP10 TFA selectively binds to lipoteichoic acid (LTA), lipopolysaccharide (LPS) and phosphatidylinositol-4,5-bisphosphate (PIP₂). PBP10 TFA penetrates cell membranes and possesses bactericidal, anti-inflammatory, cell motility-inhibiting and actin assembly-regulating activities. PBP10 TFA is applicable to relevant research on bacterial infections, microbe-induced inflammation, skin and soft tissue infections, as well as sepsis .

HY-P3828

Biotin-myelin basic protein (94-102)	Fluorescent Dye	Neurological Disease
Biotin-myelin basic protein (94-102) is a peptide fragemt. Myelin basic protein is responsible for adhesion of the cytosolic surfaces of multilayered compact myelin, it plays an important role in the process of myelination of nerves in the nervous system. Myelin basic protein also acts as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin .

HY-P5455

S3 Fragment	LIM Kinase (LIMK)	Others
S3 Fragment is a biological active peptide. (This peptide contains the unique amino-terminal phosphorylation site of Xenopus ADF/cofilin, the LIM kinase (LIMK) phosphorylation site. LIMK1 is a key regulator of the actin cytoskeleton through its phosphorylation of ADF/cofilin at serine-3 for inactivation. This peptide is a fragment of the S3 peptide containing the serine-3 sequence of ADF/cofilin that has been widely used as an effective competitive inhibitor of LIMK1.)

HY-P10651

Lifeact peptide	Biochemical Assay Reagents	Others
Lifeact peptide is a 17-amino-acid sequence derived from an actin-binding domain of yeasts. Lifeact peptide can specifically bind to actin microfilaments and can be used for the labeling of *actin* .

HY-P1045

187-1, N-WASP inhibitor 1 Publications Verification	Arp2/3 Complex	Others
187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC₅₀ of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .

HY-P10993

CT20p	Bcl-2 Family	Cancer
CT20p is an anticancer peptide based on the C hydrophobic terminus of Bax. CT20p has a unique cytotoxic effect independent of full-length Bax, and can act on mitochondria, leading to fusion-like aggregation and mitochondrial membrane hyperpolarization. CT20p can reduce α5β1 integrin levels and inhibit *F-actin* polymerization, thereby destroying the cytoskeleton and preventing cell attachment. CT20p can be used in the study of breast cancer .

HY-P10106

TAT-PAK18 inhibitory peptide	PAK	Cancer
TAT-PAK18 inhibitory peptide is a membrane-permeable PAK inhibitory peptide. TAT-PAK18 inhibitory peptide reduces F-actin clusters and occludes the effect of Shank3 knockdown .

HY-P11140

KSL-W	Bacterial Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology
KSL-W is a multifunctional antibacterial peptide with immune regulatory function. KSL-W has a chemotactic effect on neutrophils. KSL-W can induce neutrophil F-actin polymerization dependent on the Gαi protein signaling pathway. KSL-W can inhibit the production of reactive oxygen species (ROS) in neutrophils. KSL-W can be used for research on infection control and inflammation regulation .

HY-P5350

FN-A208 fusion peptide	Peptides	Others
FN-A208 is a biological active peptide. (This peptide is a fusion of A208, derived from murine laminin a1, and the active site of fibronectin (GRGDS), with a glycine spacer. This peptide forms amyloid-like fibrils and promotes formation of actin stress fibers that mediate fibroblast cell attachment, offering it potential as a bioadhesive for tissue regeneration and engineering. FN-A208 interacts with IKVAV receptors and integrins. Its activity is disrupted by the presence of EDTA.)

HY-P1045A

187-1, N-WASP inhibitor TFA	Arp2/3 Complex	Others
187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC₅₀ of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .

HY-P4948

Coumarin-Phalloidin	Biochemical Assay Reagents	Others
Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .

Cat. No.	Product Name

HY-K0903

Rhodamine Phalloidin 5+ Cited Publications
MCE Rhodamine Phalloidin is Phalloidin conjugated to the fluorescent dye Tetramethylrhodamine. Phalloidin binds F-actins with high selectivity while Rhodamine provides stable and bright orange fluorescence.

HY-K0902

Fluorescein Phalloidin 5+ Cited Publications
MCE Fluorescein Phalloidin is Phalloidin conjugated to the fluorescent dye Fluorescein. Phalloidin binds F-actins with high selectivity while Fluorescein provides stable and bright green fluorescence.

HY-K0901

AMCA Phalloidin
MCE AMCA Phalloidin is Phalloidin conjugated to the fluorescent dye AMCA. Phalloidin binds F-actins with high selectivity while AMCA provides stable and bright blue fluorescence.

Cat. No.	Product Name	Target	Research Area	Image

HY-P991423

MEDI0639 21H3RK	Notch	Cancer
MEDI0639 (21H3RK) is a human monoclonal antibody (mAb) targeting DLL4. MEDI0639 inhibits Notch1 binding to Dll4. MEDI0639 reverses Notch1-mediated growth inhibition of human umbilical vein endothelial cells in vitro. MEDI0639 promotes human angiogenesis and reduces the number of vessels covered by smooth muscle actin-positive mural cells. MEDI0639 can be used in Small cell lung cancer and solid tumors research .

HY-P992439

PF-06747143	CXCR	Cancer
PF-06747143 is recombinant anti-human antibody targeting CXCR4. PF-06747143 blocks CXCL12-induced calcium flux, F-actin polymerization, chemotaxis, cell migration, and leukemic cell bone marrow homing. PF-06747143 reduces tumor burden and improves survival in mouse models of hematologic malignancies. PF-06747143 can be used for the research of chronic lymphocytic leukemia, acute myeloid leukemia, and hematologic malignancies .

Species:	Human (10)
Tag:	SUMO (1) His (7) Strep (2) Tag Free (3) GST (2)
Source:	Sf9 insect cells (4) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P76733

	ARP3/ACTR3 Protein, Human (sf9, His-GST) Actin-related protein 3; Actin-like protein 3	Human	Sf9 insect cells
	The ARP3/ACTR3 protein is an ATPase that is preferentially stimulated by single-stranded DNA and plays a crucial role in homologous recombination repair (HRR). Independent of its ATPase function, it exhibits DNA-binding activity. ARP3/ACTR3 Protein, Human (sf9, His-GST) is the recombinant human-derived ARP3/ACTR3 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P7453

	ACTB Protein, Human (His) rHuACTB, His; Actin cytoplasmic 1; ACTB	Human	E. coli
	ACTB Protein, Human (His) is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Phe375) of Human ACTB fused with a His tag at the C-terminus.

HY-P72116

	CAPZA2 Protein, Human (His-SUMO) CAPPA2 ; Capping protein Actin filament; muscle Z line; alpha 2 ; CapZ alpha 2; CapZ alpha-2; CAPZ; CAPZA2; CAZA2_HUMAN; F Actin capping protein alpha 2 subunit; F Actin capping protein subunit alpha 2; F-Actin-capping protein subunit alpha-2	Human	E. coli
	The CAPZA2 protein is a member of the F-actin capping protein family and binds to the barbed ends of actin filaments, preventing subunit exchange without severing the filaments. CAPZA2 Protein, Human (His-SUMO) is the recombinant human-derived CAPZA2 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P75601

	CAPG Protein, Human Macrophage-capping protein; Actin regulatory protein CAP-G; CAPG; AFCP; MCP	Human	E. coli
	Macrophage-capping protein (CAPG), a ubiquitous actin-binding protein, belongs to the gelsolin/villin superfamily and is associated with cell motility. CAPG is a Ca²⁺-sensitive protein and plays a role in macrophage function and is involved in the process of metastasis by promoting the invasiveness of tumor cells. CAPG Protein, Human is the recombinant human-derived CAPG protein, expressed by E. coli , with tag free.

HY-P76470

	KLHL2 Protein, Human (His) Kelch-like protein 2; Actin-binding protein Mayven; KLHL2	Human	E. coli
	KLHL2 is a substrate-specific linker in the BCR E3 ubiquitin ligase complex that directs ubiquitination and proteasomal degradation of targets such as NPTXR, WNK1, WNK3, and WNK4. KLHL2 is critical for cellular homeostasis and catalyzes NPTXR ubiquitination, emphasizing its role in targeted protein turnover. KLHL2 Protein, Human (His) is the recombinant human-derived KLHL2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701570

	IPP Protein, Human (sf9) IPP; Actin-binding protein IPP; Intracisternal A particle-promoted polypeptide; IPP; Kelch-like protein 27	Human	Sf9 insect cells
	IPP may organize the actin cytoskeleton, affecting the structural arrangement and dynamics of the cell's cytoskeletal network. It contributes to the organization of actin filaments, which is critical for cell morphology, movement and signaling. IPP Protein, Human (sf9) is the recombinant human-derived IPP protein, expressed by sf9 insect cells , with tag free.

HY-P701571

	IPP Protein, Human (sf9, His, StrepⅡ) IPP; Actin-binding protein IPP; Intracisternal A particle-promoted polypeptide; IPP; Kelch-like protein 27	Human	Sf9 insect cells
	IPP may organize the actin cytoskeleton, affecting the structural arrangement and dynamics of the cell's cytoskeletal network. It contributes to the organization of actin filaments, which is critical for cell morphology, movement and signaling. IPP Protein, Human (sf9, His, Strep) is the recombinant human-derived IPP protein, expressed by sf9 insect cells , with N-Strep, N-8*His labeled tag.

HY-P703323

	MYO3A Protein, Human (Active, sf9, His, GST, Strep) Myosin-IIIa; MYO3A; Homo sapiens; Human; Actin-binding; Kinase; Motor protein; Myosin; Serine/threonine-protein kinase; Transferase; 2.7.11.1	Human	Sf9 insect cells
	MYO3A Protein, Human (Active, sf9, His, GST, Strep) is the recombinant human-derived MYO3A, expressed by sf9 insect cells , with Strep, His, GST labeled tag. ,

HY-P701528

	HLTF Protein, Human HLTF; Helicase-like transcription factor; DNA-binding protein/plasminogen activator inhibitor 1 regulator; HIP116; RING finger protein 80; RING-type E3 ubiquitin transferase HLTF; SWI/SNF-related matrix-associated Actin-dependent regulator of chromatin subfamily A member 3; Sucrose nonfermenting protein 2-like 3	Human	E. coli
	HLTF protein has helicase and E3 ubiquitin ligase activities and has intrinsic ATP-dependent nucleosome remodeling ability. It is critical for the transcriptional regulation of specific promoters such as SERPINE1, HIV-1 and SV40. HLTF Protein, Human is the recombinant human-derived HLTF protein, expressed by E. coli , with tag free.

HY-P701529

	HLTF Protein, Human (His) HLTF; Helicase-like transcription factor; DNA-binding protein/plasminogen activator inhibitor 1 regulator; HIP116; RING finger protein 80; RING-type E3 ubiquitin transferase HLTF; SWI/SNF-related matrix-associated Actin-dependent regulator of chromatin subfamily A member 3; Sucrose nonfermenting protein 2-like 3	Human	E. coli
	HLTF protein has helicase and E3 ubiquitin ligase activities and has intrinsic ATP-dependent nucleosome remodeling ability. It is critical for the transcriptional regulation of specific promoters such as SERPINE1, HIV-1 and SV40. HLTF Protein, Human (His) is the recombinant human-derived HLTF protein, expressed by E. coli , with N-6*His labeled tag.

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Host:	Mouse (31) Rabbit (33)
Reactivity:	Human (61) VariousPlants (1) Bovine (1) Rat (36) Monkey (6) Rabbit (2) Zebrafish (2) Oryza sativa L (1) Chick (3) Pig (4) Plant (1) Fruit Fly (1) Mouse (44) Brassica napus (1) Bovin (3) Chicken (1) Dog (1) Hamster (1)
Application:	IHC-P (48) ICC/IF (40) mIHC (1) IF-Tissue (3) IP (16) IHC-F (6) WB (56) ChIP (1) FC (17) ELISA (19)
Isotype:	IgG,Kappa (2) IgG2a,IgG/Kappa (1) IgG (33) IgG1 (16) IgG/Kappa (1) IgG2a (1) IgG2b (2)
Conjugation:	HRP (1) Non-conjugated (63)
Clonality:	Polyclonal (2) Monoclonal (47) Monoclonal Antibody (2) Recombinant (20)
Modification:	Unmodified (51)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81258A

	*alpha Skeletal Muscle Actin* Antibody (YA931)** ACTA1; ACTA; Actin; alpha skeletal muscle; Alpha-Actin-1	IHC-P	Human
	alpha Skeletal Muscle Actin Antibody (YA931) is a rabbit-derived non-conjugated IgG monoclonal antibody (Clone NO.: YA931), targeting alpha Skeletal Muscle Actin. It can be used as a loading control antibody.

HY-P81258AA

	*alpha Skeletal Muscle Actin* Antibody (YA931)(PBS only)** ACTA1; ACTA; Actin; alpha skeletal muscle; Alpha-Actin-1	IHC-P	Human
	alpha Skeletal Muscle Actin Antibody (YA931) is a rabbit-derived non-conjugated IgG monoclonal antibody (Clone NO.: YA931), targeting alpha Skeletal Muscle Actin. It can be used as a loading control antibody.

HY-P85028

	*alpha Smooth Muscle Actin* Antibody (YA4720)** ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-Actin-2; Cell growth-inhibiting gene 46 protein	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Monkey
	alpha Smooth Muscle Actin Antibody (YA4720) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to alpha Smooth Muscle Actin.

HY-P85827

	Actin smooth muscle (SMA) Antibody (YA5519) a Actin; AAT6; ACTA; ACT; ACTA3; ACTE; ACTG2; ACTH_HUMAN; Actin; Actin gamma 2 smooth muscle enteric; Actin gamma enteric smooth muscle; Actin like protein; ACTL3; ACTSG; Alpha Actin 3; Alpha-Actin-3; Gamma 2 Actin; Gamma-2-Actin; gamma-enteric smooth muscle; Smooth muscle gamma Actin; Smooth muscle gamma-Actin	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Actin smooth muscle (SMA) Antibody (YA5519) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Actin smooth muscle (SMA).

HY-P83730

	*Beta Actin* Antibody(YA3459)** 1 Publications Verification Actin; ACTB; BETA-Actin; beta Actin; Actin beta	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	Beta Actin Antibody is a non-conjugated and Rabbit origined IgG monoclonal antibody, targeting to Beta Actin. It can be used as a loading control antibody.

HY-P81258

	*alpha Skeletal Muscle Actin* Antibody (YA930)** ACTA1; ACTA; Actin; alpha skeletal muscle; Alpha-Actin-1	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	alpha Skeletal Muscle Actin Antibody (YA930) is a mouse-derived non-conjugated IgG monoclonal antibody (Clone NO.: YA930), targeting alpha Skeletal Muscle Actin. It can be used as a loading control antibody.

HY-P81254

	*Beta Actin* (Fruit Fly) Antibody** ACT1_DROME; Dro-Actin; Actin 5C; Act5C; Fruit Fly Actin; β-Actin; β Actin;	WB	Fruit Fly
	Beta Actin (Fruit Fly) Antibody is a non-conjugated and Rabbit origined IgG polyclonal antibody, targeting to Beta Actin (Fruit Fly). It can be used as a loading control antibody.

HY-P85828

	Actin Muscle Specific Antibody (YA5520) Actin, alpha cardiac muscle 1; Alpha-cardiac Actin; Actin, alpha skeletal muscle; Alpha-Actin-1; Actin, gamma-enteric smooth muscle; Alpha-Actin-3; Gamma-2-Actin; Smooth muscle gamma-Actin	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat, Monkey, Bovin, Pig, Chick
	Actin Muscle Specific Antibody (YA5520) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Actin Muscle Specific.

HY-P84429

	*alpha Smooth Muscle Actin* Antibody (YA4126)** ACTA2; AAT6; ACTSA; ACTA2; α-Smooth Muscle Actin; Alpha-Actin-2; Alpha Actin 2	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Rabbit, Monkey
	alpha Smooth Muscle Actin Antibody (YA4126) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to alpha Smooth Muscle Actin.

HY-P84429A

	*alpha Smooth Muscle Actin* Antibody (YA4126)(PBS only)** ACTA2; AAT6; ACTSA; ACTA2; α-Smooth Muscle Actin; Alpha-Actin-2; Alpha Actin 2	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Rabbit, Monkey
	alpha Smooth Muscle Actin Antibody (YA4126) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to alpha Smooth Muscle Actin.

HY-P80484

	*alpha smooth muscle Actin* Antibody (YA627)** 4 Publications Verification alpha sarcomeric Actin; alpha smooth muscle Actin; Actin alpha; ASMA; ASM-A; alpha-SMA; alpha SMA; AAT6; ACTA2; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; ACTSA; ACTVS; Alpha 2 Actin; Alpha-Actin 2; Cell growth inhibiting gene 46 protein; Growth inhibiting gene 46; ACTA_HUMAN; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; Actin, aortic smooth muscle; Alpha 2 Actin; Alpha Actin 2; Alpha cardiac Actin; Alpha-Actin 2; Alpha-Actin-2; Cell growth inhibiting gene 46 protein; Cell growth-inhibiting gene 46 protein; Growth inhibiting gene 46; MYMY5 α-Smooth Muscle Actin; α Smooth Muscle Actin;	WB, IHC-P, FC, IP	Human, Mouse
	alpha smooth muscle Actin Antibody is a non-conjugated and Rabbit origined IgG monoclonal antibody, targeting to alpha smooth muscle Actin. It can be used as a loading control antibody.

HY-P83739

	*alpha smooth muscle Actin* Antibody(YA3468)** alpha sarcomeric Actin; alpha smooth muscle Actin; Actin alpha; ASMA; ASM-A; alpha-SMA; alpha SMA; AAT6; ACTA2; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; ACTSA; ACTVS; Alpha 2 Actin; Alpha-Actin 2; Cell growth inhibiting gene 46 protein; Growth inhibiting gene 46; ACTA_HUMAN; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; Actin, aortic smooth muscle; Alpha 2 Actin; Alpha Actin 2; Alpha cardiac Actin; Alpha-Actin 2; Alpha-Actin-2; Cell growth inhibiting gene 46 protein; Cell growth-inhibiting gene 46 protein; Growth inhibiting gene 46; MYMY5 α-Smooth Muscle Actin; α Smooth Muscle Actin;	WB, IHC-P, ICC/IF, FC, IF-Tissue, mIHC	Human, Mouse, Rat
	alpha smooth muscle Actin Antibody(YA3468) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to alpha smooth muscle Actin.

HY-P85681

	*alpha Skeletal Muscle Actin* Antibody (YA5373)** ACTA1; ACTA; Actin, alpha skeletal muscle; Alpha-Actin-1	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	alpha Skeletal Muscle Actin Antibody (YA5373) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to alpha Skeletal Muscle Actin.

HY-P86727

	*alpha smooth muscle Actin* Antibody (YA6419)** alpha sarcomeric Actin; alpha smooth muscle Actin; Actin alpha; ASMA; ASM-A; alpha-SMA; alpha SMA; AAT6; ACTA2; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; ACTSA; ACTVS; alpha 2 Actin; alpha-Actin 2; Cell growth inhibiting gene 46 protein; Growth inhibiting gene 46; ACTA_HUMAN; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; Actin, aortic smooth muscle; alpha 2 Actin; alpha Actin 2; alpha cardiac Actin; alpha-Actin 2; alpha-Actin-2; Cell growth inhibiting gene 46 protein; Cell growth-inhibiting gene 46 protein; Growth inhibiting gene 46; MYMY5	WB, IHC-P, IHC-F, ICC/IF, FC, IF-Tissue	Human, Mouse, Rat
	alpha smooth muscle Actin Antibody (YA6419) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to alpha smooth muscle Actin.

HY-P86727A

	*alpha smooth muscle Actin* Antibody (YA6419)(PBS only)** alpha sarcomeric Actin; alpha smooth muscle Actin; Actin alpha; ASMA; ASM-A; alpha-SMA; alpha SMA; AAT6; ACTA2; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; ACTSA; ACTVS; alpha 2 Actin; alpha-Actin 2; Cell growth inhibiting gene 46 protein; Growth inhibiting gene 46; ACTA_HUMAN; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; Actin, aortic smooth muscle; alpha 2 Actin; alpha Actin 2; alpha cardiac Actin; alpha-Actin 2; alpha-Actin-2; Cell growth inhibiting gene 46 protein; Cell growth-inhibiting gene 46 protein; Growth inhibiting gene 46; MYMY5	WB, IHC-P, IHC-F, IF-Tissue, FC	Human, Mouse, Rat
	alpha smooth muscle Actin Antibody (YA6419) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to alpha smooth muscle Actin.

HY-P810428

	Actin Regulatory Protein CAPG Antibody (YA9741) Actin capping protein GCAP39, Actin regulatory protein CAP G, Actin regulatory protein CAP-G, AFCP, Capg, CAPG_HUMAN, Capping Actin protein gelsolin like, Capping protein (Actin filament) gelsolin like, Capping protein gelsolin like, Epididymis secretory protein Li 66	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	Actin Regulatory Protein CAPG Antibody (YA9741) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to Actin Regulatory Protein CAPG.

HY-P81035

	*Plant actin* Antibody (YA881)**	WB	Oryza sativa L, Brassica napus
	Plant actin Antibody (YA881) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Plant actin.

HY-P85948

	Actin pan Antibody (YA5640)	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat, Bovin, Pig, Chick
	Actin pan Antibody (YA5640) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Actin pan.

HY-P85650

	*Plant actin* Antibody (YA5342)**	WB	VariousPlants
	Plant actin Antibody (YA5342) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Plant actin.

HY-P80261

	*Pan-Actin* Antibody (YA694)** Actin, aortic smooth muscle Alpha-Actin-2,Cell growth-inhibiting gene 46 protein,ctin, aortic smooth muscle	WB, IHC-P	Human, Mouse, Rat
	Pan-Actin Antibody (YA694) is a non-conjugated and Mouse origined IgG1 monoclonal antibody, targeting to Pan-Actin. It can be used as a loading control antibody.

HY-P82010

	Actin Related Protein 3 Antibody (YA1755) ACTR3; ARP3; Actin-related protein 3; Actin-like protein 3	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Actin Related Protein 3 Antibody (YA1755) is a rabbit-derived non-conjugated IgG monoclonal antibody (Clone NO.: YA1755), targeting Actin Related Protein 3. It can be used as a loading control antibody.

HY-P85840

	Actin Related Protein 3 Antibody (YA5532) ACTR3; ARP3; Actin-related protein 3; Actin-like protein 3	WB, ICC/IF, ELISA	Human, Mouse, Rat
	Actin Related Protein 3 Antibody (YA5532) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Actin Related Protein 3.

HY-P80993

	*Beta Actin* Antibody (HRP)(YA4634)**	WB	Human, Mouse, Rat, Zebrafish, Monkey, Hamster, Plant
	Beta Actin Antibody (HRP)(YA4634) is a rabbit-derived HRP-conjugated IgG monoclonal antibody targeting beta-Actin.

HY-P87821

	*β-actin* Antibody (YA7506)**	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	β-actin Antibody (YA7506) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to β-actin.

HY-P85947

	Actin_sarcomeric muscle Antibody (YA5639)	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat, Bovin, Pig, Chick
	Actin_sarcomeric muscle Antibody (YA5639) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Actin_sarcomeric muscle.

HY-P80438

	*Beta Actin* Antibody (YA823)** Maximum Cited Publications 9 Publications Verification A26C1A antibody; A26C1B antibody; ACTB antibody; ACTB_HUMAN antibody; Actin beta antibody; Actin cytoplasmic 1 antibody; Actin, cytoplasmic 1, N-terminally processed antibody; Actx antibody; b Actin antibody; Beta cytoskeletal Actin antibody; Beta-Actin antibody; BRWS1 antibody; E430023M04Rik antibody; MGC128179 antibody; PS1TP5 binding protein 1 antibody; PS1TP5BP1 antibody; β-Actin antibody	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	Beta Actin Antibody is a non-conjugated and Mouse origined IgG1 monoclonal antibody, targeting to Beta Actin. It can be used as a loading control antibody.

HY-P85726

	*alpha Smooth Muscle Actin* Antibody (YA5418)** ACTA2; ACTSA; ACTVS; GIG46; Actin, aortic smooth muscle; Alpha-Actin-2; Cell growth-inhibiting gene 46 protein	WB, IHC-P	Human, Mouse, Rat
	alpha Smooth Muscle Actin Antibody (YA5418) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to alpha Smooth Muscle Actin.

HY-P87795

	*α smooth muscle actin* Antibody (YA7480)**	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	α smooth muscle actin Antibody (YA7480) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to α smooth muscle actin.

HY-P84421

	Actin Related Protein 3 Antibody (YA4118) ARP3	WB, IHC-P, FC, ELISA	Human, Mouse
	Actin Related Protein 3 Antibody (YA4118) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Actin Related Protein 3.

HY-P84422

	Actin Related Protein 3 Antibody (YA4119) ARP3	WB, IHC-P, ICC/IF, ELISA	Human, Mouse
	Actin Related Protein 3 Antibody (YA4119) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Actin Related Protein 3.

HY-P84421A

	Actin Related Protein 3 Antibody (YA4118)(PBS only) ARP3	WB, IHC-P, FC, ELISA	Human, Mouse
	Actin Related Protein 3 Antibody (YA4118) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Actin Related Protein 3.

HY-P84422A

	Actin Related Protein 3 Antibody (YA4119)(PBS only) ARP3	WB, IHC-P, ICC/IF, ELISA	Human, Mouse
	Actin Related Protein 3 Antibody (YA4119) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Actin Related Protein 3.

HY-P80667

	Fascin Antibody 55 kDa Actin bundling protein; Actin bundling protein; FAN1; Fascin 1; Fascin; Singed (Drosophila) like (sea urchin fascin homolog like); Fascin homolog 1; Fascin	WB, IHC-F, IHC-P, ICC/IF, FC, IP	Human, Mouse, Rat, Monkey
	Fascin Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Fascin.

HY-P86490

	Filamin A Antibody (YA6182) FLNA; FLN; FLN1; Filamin-A; FLN-A; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial Actin-binding protein; Filamin-1; Non-muscle filamin	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Filamin A Antibody (YA6182) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Filamin A.

HY-P85913

	Fascin Antibody (YA5605) 55 kDa Actin bundling protein; 55 kDa Actin-bundling protein; Actin bundling protein; Actin bundling protein, 55-KD; FAN 1; FAN1; Fascin 1; Fascin Actin bundling protein 1; Fascin; Fascin homolog 1 Actin bundling protein; Strongylocentrotus purpuRatus; Fascin homolog 1; Fascin, sea urchin, homolog of, 1; Fascin1; FLJ38511; FSCN 1; FSCN1; FSCN1_HUMAN; HSN; p55; Singed; Drosophila; like; sea urchin fascin homolog like; Singed drosophila homolog like; Singed like; fascin homolog sea urchin; Drosophila; Singed like; fascin homolog sea urchin; Singed like protein; Singed, drosophila, homolog of; Singed-like protein; SNL; Strongylocentrotus purpuRatus	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Fascin Antibody (YA5605) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Fascin.

HY-P82980

	Actin Related Protein 2 Antibody (YA2725) ACTR2; ARP2; ARP2/3 COMPLEX	WB, ICC/IF	Human, Mouse, Rat
	Actin Related Protein 2 Antibody (YA2725) is a rabbit-derived non-conjugated IgG monoclonal antibody (Clone NO.: YA2725), targeting Actin Related Protein 2. It can be used as a loading control antibody.

HY-P85576

	Phostensin Antibody (YA5268) HKMT1098; KIAA1949; Protein phosphatase 1 F Actin cytoskeleton targeting subunit.	WB	Human
	Phostensin Antibody (YA5268) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Phostensin.

HY-P82731

	Actin Regulatory Protein CAPG Antibody (YA2476) AFCP; Capg; gCap39; HEL S 66; mbh1; MCP	WB	Human, Mouse, Rat
	Actin Regulatory Protein CAPG Antibody (YA2476) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Actin Regulatory Protein CAPG.

HY-P82980A

	Actin Related Protein 2 Antibody (YA2725)(PBS only) ACTR2; ARP2; ARP2/3 COMPLEX	WB, ICC/IF	Human, Mouse, Rat
	Actin Related Protein 2 Antibody (YA2725) is a rabbit-derived non-conjugated IgG monoclonal antibody (Clone NO.: YA2725), targeting Actin Related Protein 2. It can be used as a loading control antibody.

HY-P86271

	ACTL8 Antibody (YA5963) ACTL8; Actin-like protein 8 ; Cancer/testis antigen 57; CT57;	WB, FC, IP	Human
	ACTL8 Antibody (YA5963) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACTL8.

HY-P82497

	GCDFP-15 Antibody (YA2242) BRST2; GCDGP15; gp17; GPIP4; PIP; ProlActin induced protein; SABP; Secretory Actin binding protein	WB, ICC/IF, IP	Human
	GCDFP-15 Antibody (YA2242) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GCDFP-15.

HY-P86264

	ACTR1B Antibody (YA5956) ACTR1B; CTRN2; Beta-centrActin ; Actin-related protein 1B; ARP1B;	WB, IHC-P, ICC/IF, FC, IP	Human
	ACTR1B Antibody (YA5956) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACTR1B.

HY-P82939

	ACTL6A Antibody (YA2684) ACTL6A; BAF53; BAF53A; INO80K; Actin-like protein 6A; 53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit K	WB, ICC/IF, IP	Human
	ACTL6A Antibody (YA2684) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACTL6A.

HY-P85915

	GCDFP-15 Antibody (YA5607) BRST-2; BRST2; GCDFP-15; GCDGP15; gp17; GPIP4; Gross cystic disease fluid protein 15; PIP; PIP_HUMAN; ProlActin induced protein; ProlActin inducible protein precursor; ProlActin-induced protein; ProlActin-inducible protein; SABP; Secretory Actin binding protein; Secretory Actin-binding protein	IHC-P, WB, ICC/IF, ELISA	Human
	GCDFP-15 Antibody (YA5607) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GCDFP-15.

HY-P82939A

	ACTL6A Antibody (YA2684)(PBS only) ACTL6A; BAF53; BAF53A; INO80K; Actin-like protein 6A; 53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit K	WB, ICC/IF, IP	Human
	ACTL6A Antibody (YA2684) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACTL6A.

HY-P82252

	ACTN3 Antibody (YA1997) ACTN3; Alpha-Actinin-3; Alpha-Actinin skeletal muscle isoform 3; F-Actin cross-linking protein	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	ACTN3 Antibody (YA1997) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ACTN3.

HY-P82158

	Sarcomeric alpha Actinin Antibody (YA1903) Actin binding protein; Actinin alpha 2; ACTN2; Alpha Actinin 2; CMD1AA	WB, IHC-P, IP	Human, Mouse, Rat
	Sarcomeric alpha Actinin Antibody (YA1903) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Sarcomeric alpha Actinin.

HY-P86079

	Sarcomeric alpha Actinin Antibody (YA5771) ACTN2; Alpha-Actinin-2; Alpha-Actinin skeletal muscle isoform 2; F-Actin cross-linking protein	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Sarcomeric alpha Actinin Antibody (YA5771) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Sarcomeric alpha Actinin.

HY-P85415

	Sarcomeric alpha Actinin Antibody (YA5107) ACTN2; Alpha-Actinin-2; Alpha-Actinin skeletal muscle isoform 2; F-Actin cross-linking protein	WB, ICC/IF	Human, Rat, Bovine, Chicken, Dog, Pig, Zebrafish
	Sarcomeric alpha Actinin Antibody (YA5107) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Sarcomeric alpha Actinin.

HY-P81344

	LSP1 Antibody (YA1089) Lymphocyte-specific protein 1; Protein pp52; 52 kDa phosphoprotein; Lymphocyte-specific antigen WP34; 47 kDa Actin-binding protein	IHC-P	Human
	LSP1 Antibody (YA1089) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LSP1.

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Cat. No.	Product Name		Classification

HY-159451

PROTAC SMARCA2 degrader-7		Azide
PROTAC SMARCA2 degrader-7 (Compound I-428) is a PROTAC degrader for SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A (SMARCA) SMARCA2. PROTAC SMARCA2 degrader-7 degrades SMARCA2 and SMARCA4 in MV411 with DC₅₀ of <100 and 100-500 nM. (Pink: Ligand for target protein (HY-159542); Black: Linker (HY-159538); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))

Cat. No.	Product Name		Classification

HY-132142

5-Propargylamino-dCTP		Nucleotide Analogs
5-Propargylamino-dCTP is a sustrate for DNA polymerases. 5-Propargylamino-dCTP can conjugate to molecular markers for use in nucleic acid labeling or sequence analysis. 5-Propargylamino-dCTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

HY-157651

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1'-myo-inositol-3',4'-bisphosphate ammonium		Phospholipids
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4'-bisphosphate) ammonium regulates the activity of the actin network associated with endocytic structures .

HY-174548

Human PDGFRB mRNA		mRNA
Human PDGFRB mRNA encodes the human platelet derived growth factor receptor beta (PDGFRB) protein, a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRB is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton.

HY-157699

1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium		Phospholipids
1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium is a membrane-bound signaling molecule with intracellular activity in regulating membrane trafficking and signal transduction. 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium can be used in the preparation of liposomes to enhance the efficiency of compound delivery. 1,2-Dioleoyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) ammonium can also act as a coordinator of the actin cytoskeleton and participate in the regulation of cell morphology and motility.

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