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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
76 Results for "
Advanced glycation end products
" in MedChemExpress (MCE) Product Catalog:
Products (76)
76 Results for "Advanced glycation end products" in MCE Product Catalog:
Cat. No.: HY-NP165
Synonyms: AGEs
17
Target:
Research Areas:
Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon also can cross the blood-brain barrier (BBB) .
11
11 Cited Publications
Cat. No.: HY-N0033
CAS No.: 94079-81-9
Category:
Cardiovascular Disease Callicarpa formosana Rolfe Plants Simple Phenylpropanols Verbenaceae Scrophulariaceae Phenols Polyphenols Phenylpropanoids Disease Research Fields Inflammation/Immunology Brandisia hancei Hook. f.
Target:
10
10 Cited Publications
Synonyms: Pimagedine hydrochloride; GER-11; Aminoguanidinium hydrochloride
Target:
Aminoguanidine (Pimagedine) hydrochloride is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hydrochloride can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in the research of diabetic nephropathy .
10
10 Cited Publications
Cat. No.: HY-W020772
CAS No.: 996-19-0
Synonyms: Pimagedine hemisulfate; GER-11 hemisulfate; Aminoguanidinium hemisulfate
Target:
Aminoguanidine (Pimagedine) hemisulfate is an inhibitor of diamine oxidase (DAO) and nitric oxide synthase (NOS). Aminoguanidine hemisulfate can reduce the formation of advanced glycation end products (AGEs). Aminoguanidine hemisulfate has a dose-dependent inhibitory effect on Doxorubicin (HY-15142)-induced cell apoptosis. Aminoguanidine hemisulfate has antioxidant properties. Aminoguanidine hemisulfate can be used in the research of diabetic nephropathy .
6
Target:
Research Areas:
Alagebrium chloride (ALT711) is an advanced glycation end product (AGE) inhibitor.
6
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Disease markers Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
6
6 Cited Publications
Cat. No.: HY-P2268
CAS No.: 1092460-91-7
Target:
Research Areas:
6
Target:
6
6 Cited Publications
Cat. No.: HY-P2268A
Target:
Research Areas:
4
4 Cited Publications
Synonyms: Kaempferol 3-O-neohesperidoside
Category:
Flavonols Flavonoids Typhaceae Typha orientalis Presl Metabolic Disease Phenols Polyphenols Plants Disease Research Fields
Target:
3
3 Cited Publications
Cat. No.: HY-B1392
CAS No.: 81161-17-3
Research Areas:
Esmolol hydrochloride is an ultra-short-acting cardioselective β1-adrenergic blocker. Esmolol hydrochloride exerts its antiarrhythmic effect by activating Neurokinin 1 Receptor. Esmolol hydrochloride attenuates post resuscitation myocardial dysfunction. Esmolol hydrochloride improves diabetic wound healing by inhibiting aldose reductase and the production of advanced glycation end products and promoting fibroblast migration. Esmolol hydrochloride can be used to study cardiac diseases such as arrhythmias and diabetic foot ulcers .
2
2 Cited Publications
Cat. No.: HY-N4170
CAS No.: 23725-05-5
1
Target:
Research Areas:
Acetohydroxamic acid is the inhibitor for bacterial and plant urease that can be used for chronic urinary tract infections. Acetohydroxamic acid selectively inhibits arachidonic acid 5-lipoxygenase that is useful in the research of asthma. Acetohydroxamic acid inhibits the formation of advanced glycation end products, and reduces oxidative stress and inflammatory responses. Acetohydroxamic acid exhibits antiviral activity against HIV .
1
1 Cited Publications
Cat. No.: HY-W286743
CAS No.: 5746-04-3
Synonyms: CML; N6-(Carboxymethyl)-L-lysine; Nε-(1-Carboxymethyl)-L-lysine
1
1 Cited Publications
Target:
Free Radical Scavengers TNF Receptor Interleukin Related Toll-like Receptor (TLR) Reactive Oxygen Species (ROS)
Research Areas:
NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research .
1
1 Cited Publications
Cat. No.: HY-N7628
CAS No.: 119170-52-4
Synonyms: Toralactone 9-O-β-D-gentiobioside
Category:
Cassia tora (L.) Roxb. Monophenols Leguminosae Metabolic Disease Phenols Plants Disease Research Fields
Target:
1
Target:
Research Areas:
Tenilsetam (CAS 997) is an antidementia compound. Tenilsetam is an advanced glycation end product (AGE) inhibitor. Tenilsetam inhibits early retinopathy in experimental diabetes rats .
Synonyms: LC15-0444 tartrate
Target:
Research Areas:
Gemigliptin tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive dipeptidyl peptidase-4 (DPP-4) inhibitor, with an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties. Gemigliptin tartrate can be used for the research of advanced glycation end products (AGE)-related diabetic complications .
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
