1. GPCR/G Protein
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    Autophagy
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  3. Esmolol hydrochloride

Esmolol hydrochloride 

Cat. No.: HY-B1392 Purity: 99.34%
Handling Instructions

Esmolol hydrochloride is a beta adrenergic receptor blocker.

For research use only. We do not sell to patients.

Esmolol hydrochloride Chemical Structure

Esmolol hydrochloride Chemical Structure

CAS No. : 81161-17-3

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 66 In-stock
Estimated Time of Arrival: December 31
Solid
10 mg USD 60 In-stock
Estimated Time of Arrival: December 31
50 mg USD 90 In-stock
Estimated Time of Arrival: December 31
100 mg USD 120 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Esmolol hydrochloride:

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Esmolol hydrochloride

  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

Esmolol hydrochloride is a beta adrenergic receptor blocker.

IC50 & Target

Adrenergic receptor

In Vitro

Esmolol hydrochloride is the hydrochloride salt form of Esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, Esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

331.83

Formula

C₁₆H₂₆ClNO₄

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (301.36 mM)

H2O : ≥ 50 mg/mL (150.68 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0136 mL 15.0680 mL 30.1359 mL
5 mM 0.6027 mL 3.0136 mL 6.0272 mL
10 mM 0.3014 mL 1.5068 mL 3.0136 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (301.36 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.75 mg/mL (8.29 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.75 mg/mL (8.29 mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.75 mg/mL (8.29 mM); Clear solution

*All of the co-solvents are provided by MCE.
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  • Molarity Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Esmolol hydrochloride
Cat. No.:
HY-B1392
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