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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
42 Results for "
Atg4
" in MedChemExpress (MCE) Product Catalog:
Products (42)
42 Results for "Atg4" in MCE Product Catalog:
1
LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC50 of 24.5 μM and a Kd of 16 μM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo .
Target:
Research Areas:
Atg4B-IN-2 is a potent competitive Atg4B inhibitor with Ki value of 3.1 μM, also possesses declining PLA2 inhibitory potency, IC50s of 11 μM and 3.5 μM for Atg4B and PLA2, respectively. Atg4B-IN-2 enhances the anticancer activity of anti-castration-resistant prostate cancer agents via autophagy inhibition .
Cat. No.: HY-170515
CAS No.: 69909-92-8
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RNF5 agonist 1 (analog-1), a structural analog of RNF5 inhibitor inh-02 (HY-123967), is a potent RNF5 agonist. RNF5 agonist 1 increases the ubiquitylation status of ATG4B in F508del-CFTR-expressing CFBE41o- cells .
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Research Areas:
RNF5 inhibitor inh-02 is a potent inhibitor of E3 ubiquitin ligase RNF5/RMA1. RNF5 inhibitor inh-02 rescues F508del-CFTR function in F508del-CFTR-expressing immortalized cells (CFBE41o⁻, EC50 = 2.6 μM; FRT, EC 50 = 2.2 μM). RNF5 inhibitor inh-02 increases LC3IIB expression and autophagic vacuole number via reducing ATG4B ubiquitylation and promotes cell motility. RNF5 inhibitor inh-02 can be used for the study of cystic fibrosis .
Cat. No.: HY-W287569
CAS No.: 370073-65-7
STK683963 is a strong activator of cellular ATG4B activity. STK683963 can act as a mediator of redox-regulation of ATG4B in cells. STK683963 can be used for the research of cancer .
Cat. No.: HY-RS01148
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ATG4A Human Pre-designed siRNA Set A contains three designed siRNAs for ATG4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19173
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Atg4a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atg4a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25662
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Atg4a Rat Pre-designed siRNA Set A contains three designed siRNAs for Atg4a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01149
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ATG4B Human Pre-designed siRNA Set A contains three designed siRNAs for ATG4B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01150
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ATG4C Human Pre-designed siRNA Set A contains three designed siRNAs for ATG4C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS01151
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ATG4D Human Pre-designed siRNA Set A contains three designed siRNAs for ATG4D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19174
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Atg4c Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atg4c gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22398
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Atg4d Mouse Pre-designed siRNA Set A contains three designed siRNAs for Atg4d gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23372
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Atg4b Rat Pre-designed siRNA Set A contains three designed siRNAs for Atg4b gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28922
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Atg4d Rat Pre-designed siRNA Set A contains three designed siRNAs for Atg4d gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P7618
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Atg4A; Atg4 Autophagy Related 4 Homolog A (S. Cerevisiae); Prev. APG4A; Autophagy Related 4A, Cysteine Peptidase; Prev. AUTL2; Atg4 Autophagy Related 4 Homolog A; Autophagy-Related Cysteine Endopeptidase 2; AUT-Like 2, Cysteine Endopeptidase; Autophagy-Re
Species:
Human
Source:
E. coli
Cat. No.: HY-P7619
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Atg4C; HsAPG4C; Prev. APG4C; Atg4 Autophagy Related 4 Homolog C (S. Cerevisiae); Prev. AUTL1; APG4 Autophagy 4 Homolog C (S. Cerevisiae); AUTL3; Epididymis Secretory Sperm Binding Protein; Autophagy-Related Cysteine Endopeptidase 3; Autophagy Related 4C,
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
