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Bovine Protein C

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) APC (1) Apoptosis (2) Bacterial (1) Biochemical Assay Reagents (1) Calmodulin (1) Caspase (1) Fluorescent Dye (2) Glutamate Dehydrogenase (GLDH) (2) MMP (1) P-glycoprotein (1) Phosphodiesterase (PDE) (3) PKC (3) PTHR (1) Reactive Oxygen Species (ROS) (1) Ser/Thr Protease (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (2) Infection (1) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

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Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-137592

Nicotinamide 1,N6-ethenoadenine dinucleotide ε-NAD	Fluorescent Dye Phosphodiesterase (PDE) Glutamate Dehydrogenase (GLDH)	Others
Nicotinamide 1,N6-ethenoadenine dinucleotide (ε-NAD) is a fluorescent analog of NAD. Nicotinamide 1,N6-ethenoadenine dinucleotide can be cleaved by phosphodiesterase I (from C. adamanteus venom) and binds to bovine liver glutamate dehydrogenase. Nicotinamide 1,N6-ethenoadenine dinucleotide can serve as a substrate for G-ADP ribosylation of G proteins catalyzed by bacterial toxins. Nicotinamide 1,N6-ethenoadenine dinucleotide can be used as a fluorescent substrate for the study of ADP ribosylation reactions .

HY-125857C

Cytochrome C (bovine heart)	Biochemical Assay Reagents Apoptosis Reactive Oxygen Species (ROS) Caspase	Metabolic Disease
Cytochrome C (bovine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (bovine heart) acts as an effective ROS scavenger, but when combined with the cofactor p66Shc, it promotes the generation of ROS to initiate apoptosis. Cytochrome C (bovine heart) can act as a single electron carrier .

HY-P10856

CPI1	P-glycoprotein	Cancer
CPI1 is a multidrug resistance protein 1 (MRP1) inhibitor with a K_i value of 100 nM. CPI1 binds to the same substrate-binding site as leukotriene C₄, stabilizes MRP1 in an apo-like inward-facing conformation, blocks the conformational changes required for ATP hydrolysis and substrate transport, and inhibits the ATPase activity of human and bovine MRP1. CPI1 serves as a tool for investigating the substrate transport mechanism of MRP1. CPI1 is applicable to research related to cancer multidrug resistance .

HY-19820A

NSC45586 sodium 1 Publications Verification	Akt Ser/Thr Protease Apoptosis MMP	Cardiovascular Disease Neurological Disease Inflammation/Immunology
NSC45586 sodium is an inhibitor of PHLPP. NSC45586 sodium targets the *PP2C* phosphatase domains of PHLPP1 and PHLPP2, blocks the phosphatase activity of PHLPP, increases the expression level of FOXO1 in the nucleus, and reduces the protein expression of PHLPP1. NSC45586 sodium activates the AKT survival signaling pathway, enhances IGF-1-induced AKT activation, and inhibits the phosphorylation of AKT/ERK under basal conditions. NSC45586 sodium reduces staurosporine-induced neuronal death, preserves notochord cell morphology and KRT19 expression, inhibits cell apoptosis (apoptosis), improves the viability and proliferation of nucleus pulposus cells, upregulates the expression of ACAN/SOX9, and downregulates the expression of MMP13. NSC45586 sodium binds tightly to bovine serum albumin (bovine serum albumin), and exerts a more significant effect on nucleus pulposus in male individuals. NSC45586 sodium can be used in studies related to global cerebral ischemia and intervertebral disc degeneration .

HY-P5125

Z-Arg-SBzl	PKC	Others
Z-Arg-SBzl is a substrate of both bovine and activated human protein C .

HY-P4798

Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) Human PTHrP(107-111) amide	PTHR	Others
Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroid hormone-related protein fragment that can inhibit bone resorption .

HY-112968A

Bovine Protein C	APC	Cardiovascular Disease
Bovine Protein C is activated by α-thrombin or α-thrombin/thrombomodulin complex to a serine protease, namely activated protein C (APC). Bovine Protein C can selectively inactivate factors Va and VIIIa and is a potent anticoagulant .

HY-NP0230

Bovine calmodulin	Calmodulin	Neurological Disease
Bovine calmodulin can be used for the in vitro phosphorylation assay of recombinant retinoic acid-induced gene I protein. Bovine calmodulin has also been used in studies of the hydrolysis and deamidation of the endopeptide Glu-C protein .

HY-P5125A

Z-Arg-SBzl TFA	PKC	Others
Z-Arg-SBzl TFA is a substrate of both bovine and activated human protein C .

HY-114554

KS 619-1	Phosphodiesterase (PDE) PKC Bacterial	Infection
KS 619-1 is a Ca ²⁺/calmodulin-dependent cyclic nucleotide phosphodiesterase inhibitor. KS 619-1 exhibits strong inhibitory activity against this enzyme derived from bovine brain and heart, but shows weak inhibitory effects on calmodulin-independent phosphodiesterase and protein kinase C. KS 619-1 displays weak antibacterial activity against Staphylococcus aureus .

HY-DY1108

Nicotinamide 1,N6-ethenoadenine dinucleotide (solution) ε-NAD (solution)	Glutamate Dehydrogenase (GLDH) Phosphodiesterase (PDE) Fluorescent Dye	Others
Nicotinamide 1,N6-ethenoadenine dinucleotide (solution) (ε-NAD (solution)) is a fluorescent analog of NAD. Nicotinamide 1,N6-ethenoadenine dinucleotide can be cleaved by phosphodiesterase I (from C. adamanteus venom) and binds to bovine liver glutamate dehydrogenase. Nicotinamide 1,N6-ethenoadenine dinucleotide can serve as a substrate for G-ADP ribosylation of G proteins catalyzed by bacterial toxins. Nicotinamide 1,N6-ethenoadenine dinucleotide can be used as a fluorescent substrate for the study of ADP ribosylation reactions . Solvent and concentration: ddH2O: 20 mM

Cat. No.	Product Name	Type

HY-125857C

Cytochrome C (bovine heart)	Biochemical Assay Reagents
Cytochrome C (bovine heart) is composed of 104 amino acids and is a nuclear-encoded mitochondrial protein. Cytochrome C (bovine heart) acts as an effective ROS scavenger, but when combined with the cofactor p66Shc, it promotes the generation of ROS to initiate apoptosis. Cytochrome C (bovine heart) can act as a single electron carrier .

HY-NP0230

Bovine calmodulin	Biochemical Assay Reagents
Bovine calmodulin can be used for the in vitro phosphorylation assay of recombinant retinoic acid-induced gene I protein. Bovine calmodulin has also been used in studies of the hydrolysis and deamidation of the endopeptide Glu-C protein .

Cat. No.	Product Name	Target	Research Area

HY-P10856

CPI1	P-glycoprotein	Cancer
CPI1 is a multidrug resistance protein 1 (MRP1) inhibitor with a K_i value of 100 nM. CPI1 binds to the same substrate-binding site as leukotriene C₄, stabilizes MRP1 in an apo-like inward-facing conformation, blocks the conformational changes required for ATP hydrolysis and substrate transport, and inhibits the ATPase activity of human and bovine MRP1. CPI1 serves as a tool for investigating the substrate transport mechanism of MRP1. CPI1 is applicable to research related to cancer multidrug resistance .

HY-P5125

Z-Arg-SBzl	PKC	Others
Z-Arg-SBzl is a substrate of both bovine and activated human protein C .

HY-P4798

Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) Human PTHrP(107-111) amide	PTHR	Others
Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) (Human PTHrP (107-111) amide) is a C-terminal parathyroid hormone-related protein fragment that can inhibit bone resorption .

HY-P5125A

Z-Arg-SBzl TFA	PKC	Others
Z-Arg-SBzl TFA is a substrate of both bovine and activated human protein C .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-114554

KS 619-1	Structural Classification Microorganisms Xanthones Phenols Source Classification	Phosphodiesterase (PDE) PKC Bacterial
KS 619-1 is a Ca ²⁺/calmodulin-dependent cyclic nucleotide phosphodiesterase inhibitor. KS 619-1 exhibits strong inhibitory activity against this enzyme derived from bovine brain and heart, but shows weak inhibitory effects on calmodulin-independent phosphodiesterase and protein kinase C. KS 619-1 displays weak antibacterial activity against Staphylococcus aureus .

Species:	Bovine (7)
Tag:	GFP (1) SUMO (3) His (7) Strep (1) Myc (1)
Source:	HEK293 (1) P. pastoris (2) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P700529

	*AIF1 Protein, Bovine* (N-His, C-Myc)** allograft inflammatory factor 1; IBA1; IRT1; AIF-1; IRT-1; Protein G1	Bovine	E. coli
	AIF1 protein influences macrophage activation, modulating immune response and cellular activities. Its involvement implies broader influence on immune regulation and inflammation. Studying AIF1's mechanisms in macrophage activation can provide insights into its role in immune homeostasis and signaling pathways governing macrophage functions. AIF1 Protein, Bovine (N-His, C-Myc) is the recombinant bovine-derived AIF1 protein, expressed by E. coli , with C-Myc, N-10*His labeled tag.

HY-P700550

	*MIP-3 alpha/CCL20 Protein, Bovine* (His-SUMO)** rHuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20	Bovine	E. coli
	The MIP-3 α/CCL20 protein acts as a ligand for CCR6, inducing an efficient chemotactic response and intracellular calcium mobilization upon CCR6 binding. The CCL20-CCR6 pair is critical in chemotaxis, attracting dendritic cells, effector/memory T cells, and B cells, especially to skin and mucosal surfaces during homeostasis, inflammation, cancer, and autoimmune diseases. MIP-3 alpha/CCL20 Protein, Bovine (His-SUMO) is the recombinant bovine-derived MIP-3 alpha/CCL20 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P700551

	*MIP-3 alpha/CCL20 Protein, Bovine* (P. pastoris, His)** rHuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20	Bovine	P. pastoris
	The MIP-3 α/CCL20 protein acts as a ligand for CCR6, inducing an efficient chemotactic response and intracellular calcium mobilization upon CCR6 binding. The CCL20-CCR6 pair is critical in chemotaxis, attracting dendritic cells, effector/memory T cells, and B cells, especially to skin and mucosal surfaces during homeostasis, inflammation, cancer, and autoimmune diseases. MIP-3 alpha/CCL20 Protein, Bovine (P. pastoris, His) is the recombinant bovine-derived MIP-3 alpha/CCL20 protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P701355

	*ABCC1 Protein, Bovine* (HEK293, GFP, StrepⅡ, His)** ABCC1; Multidrug resistance-associated Protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Bovine	HEK293
	The ABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. ABCC1 Protein, Bovine (HEK293, GFP, Strep, His) is the recombinant bovine-derived ABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-StrepII labeled tag.

HY-P72246

	*IFN-omega 1 Protein, Bovine* (His-SUMO)** IFNW1; IFNW; Interferon omega-1; IFN-omega-c1; Interferon alpha-II-1	Bovine	E. coli
	IFN-omega 1 protein is a member of the alpha/beta interferon family. IFN-omega 1 Protein, Bovine (His-SUMO) is the recombinant bovine-derived IFN-omega 1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P71552

	*Complement C3a Protein, Bovine* (His-SUMO)** C3Complement C3; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2]	Bovine	E. coli
	Complement C3/C3a proteins play a key role in initiating the complement system, serving as substrates for C3 convertase in both the classical and alternative pathways. Upon activation, C3 undergoes proteolytic cleavage, yielding C3b, which is covalently bound to surface or immune aggregates. Complement C3a Protein, Bovine (His-SUMO) is the recombinant bovine-derived Complement C3/C3a protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P71827

	*Adiponectin/Acrp30 Protein, Bovine* (P.pastoris, His)** ADIPOQ; ACRP30Adipocyte complement-related 30kDa Protein; ACRP30; Adipocyte; C1q and collagen domain-containing Protein; Adipose most abundant gene transcript 1 Protein; apM-1	Bovine	P. pastoris
	Adiponectin/Acrp30 Protein, Bovine (P.pastoris, His) can increase cell sensitivity to insulin and can be used as a potential protein for diabetic tendinopathy research.

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Bovine Protein C

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

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Recombinant Proteins

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