65 Results for "

CAD

" in MedChemExpress (MCE) Product Catalog:
Products (65)

65 Results for "CAD" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-109160
CAS No.: 2167246-24-2
Purity:  99.27%
Synonyms: CAD-1883
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Rimtuzalcap (CAD-1883) is a first-in-class selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels). Rimtuzalcap can be used for the research of movement disorders including essential tremor (ET) and spinocerebellar ataxia (SCA) .
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2
2 Cited Publications
Cat. No.: HY-P81097
Synonyms: VE-CADherin; 7B4 antigen; VECD; Vascular endothelial cell CADherin; 7B 4; 7B4; 7B4 antigen; CADherin 5; CADherin 5 type 2; CADherin-5; CADherin5; CD 144; CD144 antigen; CDH 5; CDH5; CDH5 protein; Vascular endothelial CADherin; VE CAD antibody VEC; CADH5_HUMAN.

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

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Cat. No.: HY-P99301
CAS No.: 1533403-95-0
Synonyms: Anti-Canine IL31 Recombinant Antibody; CAN34D3-65; PF-06443537

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Lokivetmab (Anti-Canine IL31 Recombinant Antibody) is an anti-canine IL-31 monoclonal antibody. Lokivetmab inhibits IL-31-mediated activation of pruritogenic signals in peripheral sensory neurons and reduces TH2-weighted inflammation. Lokivetmab demonstrates long-term efficacy in controlling pruritus and improving skin lesions in dogs with canine atopic dermatitis (CAD). Lokivetmab can be used for the research of atopic dermatitis (AD) in dogs .
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Cat. No.: HY-139580
CAS No.: 2378285-59-5
Purity:  96.61%
Synonyms: CAD-9303
Target:  

iGluR

Research Areas:  

Neurological Disease

Plazinemdor (CAD-9303) is a positive allosteric modulator of N-methyl-D-aspartate (NMDA) receptors, which is used in the research of neurological diseases .
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Cat. No.: HY-137959
CAS No.: 250780-40-6
Telmisartan acyl-β-D-glucuronide is an acyl-β-D-glucuronide and a metabolite of Telmisartan (HY-13955). Telmisartan acyl-β-D-glucuronide can be converted back to Telmisartan upon incubation with Glucuronidase. Partial acyl migration of Telmisartan acyl-β-D-glucuronide occurs under physiological conditions .
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Cat. No.: HY-124609
CAS No.: 2071209-49-7
Purity:  99.39%
Research Areas:  

Neurological Disease

CAD031 is an orally active AMPK/ACC1 signaling pathway activator and a derivative of the Alzheimer's disease (AD) targeted agent J147 (HY-13779) (more active than J147 in human neural stem cell assays). CAD031 can cross the blood-brain barrier, activate AMPK and inhibit ACC1, thereby increasing ac-CoA levels, improving mitochondrial function and reducing free fatty acid synthesis. CAD031 has neuroprotective, neurogenesis-promoting and memory-improving activities and can be used in the study of Alzheimer's disease and aging-related neurodegenerative diseases. CAD031 effectively enhances the memory of mice, improves dendritic structure, and stimulates cell division in the germinal zone of the brain of elderly mice .
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Cat. No.: HY-123494
CAS No.: 1565827-99-7
Purity:  99.22%
Target:  

CaMK

BRD0418 is a diversity-oriented synthesis (DOS) molecule that regulates the expression of tribbles pseudokinase 1. BRD0418 has the effect of causing hot lipoprotein metabolism from fat production to clearance. BRD0418 can be used in the study of coronary artery disease (CAD) .
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Cat. No.: HY-P5755
Target:  

Peptides

Research Areas:  

Cancer

SWELYYPLRANL-NH2 is an E-cadherin and N-cadherin antagonist. SWELYYPLRANL-NH2 inhibits phage clone binding to E- or N-cad/Fc chimeric protein (IC50: 0.7 and 0.09 μM respectively). SWELYYPLRANL-NH2 inhibits cell aggregation. SWELYYPLRANL-NH2 can be used to promote drug delivery through epithelial and endothelial permeability barriers .
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Cat. No.: HY-128912
CAS No.: 5489-57-6
Purity:  99.87%
Category:  

Alkaloids Animals

Target:  

Histone Demethylase

Arborinine is a potent and orally activeLSD1 inhibitor. Arborinine increases the expression of H3K4me1/2, H3K9me1/2, E-cad protein and decreases the expression of UBE2O protein level. Arborinine induces cell cycle arrest at S phase. Arborinine shows antitumor activity .
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Cat. No.: HY-N1753
CAS No.: 10210-17-0
Synonyms: Dihydro-p-coumaryl alcohol; 3-(p-Hydroxyphenyl)propyl alcohol
Target:  

Endogenous Metabolite

Research Areas:  

Others

3-(4-Hydroxyphenyl)-1-propanol (Dihydro-p-coumaryl alcohol) is a metabolite. 3-(4-Hydroxyphenyl)-1-propanol can be isolated from P. radiate callus cultures. 3-(4-Hydroxyphenyl)-1-propanol is associated with CAD activity .
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Cat. No.: HY-164466
CAS No.: 2682205-20-3
Target:  

Calcium Channel Notch

Research Areas:  

Cancer

CAD204520, a SERCA inhibitor (IC50 = 0.34 μM), targets mutated over wild type NOTCH1 proteins in T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL). CAD204520 can be used for T-ALL and MCL research .
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Cat. No.: HY-RS01818
Research Areas:  

Others

CAD Human Pre-designed siRNA Set A contains three designed siRNAs for CAD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-128446
CAS No.: 1210360-87-4
Target:  

VEGFR

Research Areas:  

Neurological Disease

CAY10781 (Compound 11) is an inhibitor of the neuropilin-1 (NRP-1) and VEGF-A interaction. CAY10781 inhibits VEGF-A-induced phosphorylation of VEGFR2 in Catecholamine A-differentiated (CAD) cells [1]< sup>.
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Cat. No.: HY-RS00172
Research Areas:  

Others

ACOD1 Human Pre-designed siRNA Set A contains three designed siRNAs for ACOD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16239
Research Areas:  

Others

Acod1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acod1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS03709
Research Areas:  

Others

DFFB Human Pre-designed siRNA Set A contains three designed siRNAs for DFFB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-103406
CAS No.: 250266-51-4
PNU-177864 is a potent, selective, orally active dopamine D3 receptor antagonist. PNU-177864 induces phospholipid metabolism in vivo and has anti-schizophrenia activity .
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Cat. No.: HY-103406A
CAS No.: 1783978-03-9
Target:  

Dopamine Receptor CCR

Research Areas:  

Neurological Disease

PNU-177864 is a potent, selective, orally active dopamine D3 receptor antagonist. PNU-177864 induces phospholipid metabolism in vivo and has anti-schizophrenia activity .
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Cat. No.: HY-N1753R
CAS No.: 10210-17-0
Synonyms: Dihydro-p-coumaryl alcohol (Standard); 3-(p-Hydroxyphenyl)propyl alcohol (Standard)
Research Areas:  

Others

3-(4-Hydroxyphenyl)-1-propanol (Standard) is an analytical standard of 3-(4-Hydroxyphenyl)-1-propanol (HY-N1753). This product is intended for research and analytical applications. 3-(4-Hydroxyphenyl)-1-propanol (Dihydro-p-coumaryl alcohol) is a metabolite. 3-(4-Hydroxyphenyl)-1-propanol can be isolated from P. radiate callus cultures. 3-(4-Hydroxyphenyl)-1-propanol is associated with CAD activity .
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Cat. No.: HY-164466A
CAS No.: 2682205-21-4
Target:  

Calcium Channel Notch

Research Areas:  

Cancer

CAD204520 dihydrochloride, a SERCA inhibitor (IC50 = 0.34 μM), targets mutated over wild type NOTCH1 proteins in T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL). CAD204520 dihydrochloride can be used for T-ALL and MCL research .
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