2. Peptides
  3. SWELYYPLRANL-NH2

SWELYYPLRANL-NH2 is an E-cadherin and N-cadherin antagonist. SWELYYPLRANL-NH2 inhibits phage clone binding to E- or N-cad/Fc chimeric protein (IC50: 0.7 and 0.09 μM respectively). SWELYYPLRANL-NH2 inhibits cell aggregation. SWELYYPLRANL-NH2 can be used to promote drug delivery through epithelial and endothelial permeability barriers.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

SWELYYPLRANL-NH2 Chemical Structure

SWELYYPLRANL-NH2 Chemical Structure

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1 mg USD 50 In-stock
5 mg USD 115 In-stock
10 mg USD 184 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of SWELYYPLRANL-NH2:

SWELYYPLRANL-NH2 Related Antibodies

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Description

SWELYYPLRANL-NH2 is an E-cadherin and N-cadherin antagonist. SWELYYPLRANL-NH2 inhibits phage clone binding to E- or N-cad/Fc chimeric protein (IC50: 0.7 and 0.09 μM respectively). SWELYYPLRANL-NH2 inhibits cell aggregation. SWELYYPLRANL-NH2 can be used to promote drug delivery through epithelial and endothelial permeability barriers[1].

IC50 & Target

E-cadherin, N-cadherin[1]
Molecular Weight

1523.73

Formula

C73H106N18O18
Appearance

Solid

Color

White to off-white

Sequence

Ser-Trp-Glu-Leu-Tyr-Tyr-Pro-Leu-Arg-Ala-Asn-Leu-NH2
Sequence Shortening

SWELYYPLRANL-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (65.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6563 mL 3.2814 mL 6.5628 mL
5 mM 0.1313 mL 0.6563 mL 1.3126 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6563 mL 3.2814 mL 6.5628 mL 16.4071 mL
5 mM 0.1313 mL 0.6563 mL 1.3126 mL 3.2814 mL
10 mM 0.0656 mL 0.3281 mL 0.6563 mL 1.6407 mL
15 mM 0.0438 mL 0.2188 mL 0.4375 mL 1.0938 mL
20 mM 0.0328 mL 0.1641 mL 0.3281 mL 0.8204 mL
25 mM 0.0263 mL 0.1313 mL 0.2625 mL 0.6563 mL
30 mM 0.0219 mL 0.1094 mL 0.2188 mL 0.5469 mL
40 mM 0.0164 mL 0.0820 mL 0.1641 mL 0.4102 mL
50 mM 0.0131 mL 0.0656 mL 0.1313 mL 0.3281 mL
60 mM 0.0109 mL 0.0547 mL 0.1094 mL 0.2735 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SWELYYPLRANL-NH2Otherscell aggregationMCF-7drug deliveryInhibitorinhibitorinhibit

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