SWELYYPLRANL-NH2
Based on 1 Customer Validation
SWELYYPLRANL-NH2 is an E-cadherin and N-cadherin antagonist. SWELYYPLRANL-NH2 inhibits phage clone binding to E- or N-cad/Fc chimeric protein (IC50: 0.7 and 0.09 μM respectively). SWELYYPLRANL-NH2 inhibits cell aggregation. SWELYYPLRANL-NH2 can be used to promote drug delivery through epithelial and endothelial permeability barriers.
For research use only. We do not sell to patients.
- Purity: 99.84%
- Formula: C73H106N18O18
- Molecular Weight:1523.73
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Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
E-cadherin, N-cadherin[1]
Chemical Information
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Appearance Solid
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Molecular Weight 1523.73
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Formula C73H106N18O18
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Color White to off-white
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Sequence
Ser-Trp-Glu-Leu-Tyr-Tyr-Pro-Leu-Arg-Ala-Asn-Leu-NH2
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Sequence Shortening
SWELYYPLRANL-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (65.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6563 mL | 3.2814 mL | 6.5628 mL | 16.4071 mL |
| 5 mM | 0.1313 mL | 0.6563 mL | 1.3126 mL | 3.2814 mL | |
| 10 mM | 0.0656 mL | 0.3281 mL | 0.6563 mL | 1.6407 mL | |
| 15 mM | 0.0438 mL | 0.2188 mL | 0.4375 mL | 1.0938 mL | |
| 20 mM | 0.0328 mL | 0.1641 mL | 0.3281 mL | 0.8204 mL | |
| 25 mM | 0.0263 mL | 0.1313 mL | 0.2625 mL | 0.6563 mL | |
| 30 mM | 0.0219 mL | 0.1094 mL | 0.2188 mL | 0.5469 mL | |
| 40 mM | 0.0164 mL | 0.0820 mL | 0.1641 mL | 0.4102 mL | |
| 50 mM | 0.0131 mL | 0.0656 mL | 0.1313 mL | 0.3281 mL | |
| 60 mM | 0.0109 mL | 0.0547 mL | 0.1094 mL | 0.2735 mL |