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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
CCS
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "CCS" in MCE Product Catalog:
12
Research Areas:
Inobrodib (CCS1477) is an orally active, potent, and selective inhibitor of the p300/CBP bromodomain. Inobrodib binds to p300 and CBP with Kd values of 1.3 and 1.7 nM, respectively, and with 170/130-fold selectivity compared with BRD4 with a Kd of 222 nM. CCS1477 inhibits cell proliferation in prostate cancer cell lines and decreases androgen receptor (AR)- and C-MYC-regulated gene expression .
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6 Cited Publications
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance .
Cat. No.: HY-160005
CAS No.: 1883730-99-1
Synonyms: NSC 781517
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LMP517 (NSC 781517) is a potent and non-camptothecin Topoisomerase I and II (TOP1 and TOP2) dual inhibitor. LMP517 can induce TOP1 and TOP2 cleavage complexes (TOP1ccs and TOP2ccs). LMP517 can induce cancer cells DNA damage and γH2AX production. LMP517 can be used for the research of cancer, such as small cell lung cancer .
Cat. No.: HY-19704
CAS No.: 1233363-33-1
Synonyms: CT327; SNA-120
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Pegcantratinib (CT327) is a potent and selective TRKA antagonist with activity against TRKB and TRKC. Pegcantratinib can be used for research of CYLD cutaneous syndrome (CCS) and inflammatory dermatoses, such as psoriasis and concomitant pruritus .
Cat. No.: HY-168202
Research Areas:
CCS1477a is the active form of the target protein ligand of PROTAC degrader MJP6412 (HY-168201) .
Cat. No.: HY-RS02176
Target:
Research Areas:
CCS Human Pre-designed siRNA Set A contains three designed siRNAs for CCS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-147373
CAS No.: 2488660-12-2
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DA-PROTAC is a potent PROTAC degrader of copper ion-transport proteins Atox1 and CCS. DA-PROTAC can bind both Atox1 and CCS proteins, and the complex can be bound to E3 ligase, leading to increased levels of ubiquitination of Atox1 and CCS and degradation of Atox1 and CCS proteins via the proteasome pathway. DA-PROTAC can be used for triple negative breast cancer research .
Cat. No.: HY-RS17675
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Ccs Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccs gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24136
Target:
Research Areas:
Ccs Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccs gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-107636R
CAS No.: 497061-48-0
Target:
Research Areas:
DC_AC50 (Standard) is the analytical standard of DC_AC50 (HY-107636). This product is intended for research and analytical applications. DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance .
Cat. No.: HY-P72178
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CCS 3; CCS3; Cervical cancer suppressor 3; chunp6927; CTCL tumor antigen; EE1A1; EEF 1; EEF1A; eEF1A-1; EEF1A1; EF-1-alpha-1; EF-Tu; EF1A; EF1a like protein; EF1A1_HUMAN; Elongation factor 1-alpha 1; Elongation factor Tu; GRAF 1EF; HNGC:16303; ik:tdsubc_2a3; ik:tdsubc_2b3; LENG7; member 7; PTI1; tdsubc_2a3; wu:fa91c07; wu:fa94b03; wu:fi13b09; xx:tdsubc_2a3; xx:tdsubc_2b3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
