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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
CHIP
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "CHIP" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-18619
CAS No.: 36341-25-0
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YL-109 is an antitumor agent that can induce carboxyl terminus of Hsp70-interacting protein (CHIP) expression through aryl hydrocarbon receptor (AhR) signaling. YL-109 has ability to inhibit breast cancer cell growth and invasiveness .
2
2 Cited Publications
Cat. No.: HY-P71340
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: E3 Ubiquitin-Protein Ligase CHIP; Antigen NY-CO-7; CLL-Associated Antigen KW-8; Carboxy Terminus of Hsp70-Interacting Protein; STIP1 Homology and U Box-Containing Protein 1; STUB1; CHIP
1
1 Cited Publications
Cat. No.: HY-W123005
CAS No.: 58537-94-3
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Dimethyl pimelimidate dihydrochloride is a bifunctional imidoester protein-protein crosslinker used in chromatin immunoprecipitation (ChIP) assays .
1
Synonyms: 14-D-Valine-TPL
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WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc molecule glue degrader. WBC100 is a c-Myc degrader and targets ubiquitin E3 ligase CHIP mediated 26S proteasome pathway. WBC100 is used for c-Myc overexpressing tumors research .
Cat. No.: HY-W763582B
CAS No.: 2280018-77-9
Synonyms: Gelatin Methacryloyl, 90% methacrylation
Cat. No.: HY-W763582
CAS No.: 2280018-77-9
Synonyms: Gelatin Methacryloyl, 30% methacrylation
Cat. No.: HY-175552
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Cat. No.: HY-175686
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E3 ligase Ligand 67 (Compound 5) is a STUB1/CHIP ligand with a Kd of 8.9 μM for CHIP in fluorescence polarization assay. E3 ligase Ligand 67 is an E3 ligase ligand that can be used for synthesis of PROTACs .
Cat. No.: HY-W763582A
CAS No.: 2280018-77-9
Synonyms: Gelatin Methacryloyl, 60% methacrylation
Cat. No.: HY-148979
CAS No.: 61216-62-4
Synonyms: SAPE
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GNA002 is a highly potent, specific and covalent EZH2 (Enhancer of zeste homolog 2) inhibitor with an IC50 of 1.1 μM. GNA002 can specifically and covalently bind to Cys668 within the EZH2-SET domain, triggering EZH2 degradation through COOH terminus of Hsp70-interacting protein (CHIP)-mediated ubiquitination. GNA002 efficiently reduces EZH2-mediated H3K27 trimethylation, reactivates polycomb repressor complex 2 (PRC2)-silenced tumor suppressor genes .
Cat. No.: HY-W391506
CAS No.: 9011-14-7
Synonyms: Poly(methyl methacrylate), beads; PMMA
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Poly(methyl methacrylate) (PMMA) serves as an effective material for the production of micro-fluidic chips.
Cat. No.: HY-D1721
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Fluorescein-12-dATP is a fluorescein-labeled deoxyadenosine triphosphate and signal amplifier. Fluorescein-12-dATP can be incorporated into the 3'-end of exposed thrombin-binding aptamers via terminal deoxynucleotidyl transferase to form multi-labeled nucleic acid chains, which are used for signal amplification in thrombin detection. Fluorescein-12-dATP acts as a fluorescent detection probe in chip-based aptamer sandwich biosensors for the detection of thrombin in serum. Fluorescein-12-dATP can be used in studies related to thrombin detection .
Cat. No.: HY-RS13972
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STUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for STUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-151884
CAS No.: 1242862-71-0
FUBP1-IN-2 (compound 9) is a potent FUBP1 (far upstream binding protein 1) inhibitor. FUBP1-IN-2 inhibits the KH4 FUBP1-FUSE interaction in a gel shift assay. FUBP1-IN-2 binds to FUBP1 in a ChIP assay. FUBP1-IN-2 reduces both c-Myc mRNA and protein expression, increases p21 mRNA and protein expression, and depletes intracellular polyamines .
Cat. No.: HY-148745
CAS No.: 2241517-83-7
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JG-258 is an inactive negative control for Hsp70 inhibitors. JG-258 is an inactive structural analog of JG-98 (HY-117282), an allosteric inhibitor of heat shock protein 70 (Hsp70) with demonstrated anticancer activity. JG-258 can be used in cancer-related research .
Cat. No.: HY-W097929
CAS No.: 87-40-1
Synonyms: 2,4,6-Trichloroanisole
Research Areas:
Tyrene (2,4,6-Trichloroanisole) is an off-flavor compound, cyclic nucleotide-gated (CNG) channel inhibitor, and olfactory transduction attenuator. Tyrene is formed by microbial O-methylation of 2,4,6-trichlorophenol. Tyrene inhibits channel activity in olfactory receptor cells by partitioning into the plasma membrane lipid bilayer, and also suppresses odorant- and cAMP-induced currents in individual olfactory receptor cells. Tyrene causes cork taint in wine. Tyrene also produces off-flavors in potato chips, dried fruits, coffee, and drinking water .
Cat. No.: HY-130071
CAS No.: 62928-11-4
Synonyms: CHIP
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Iproplatin (CHIP) is an anti-cancer agent with reduced toxicity in testicular and ovarian cancers. The major reduced product of Iproplatin by glutathione is chloro-bis (isopropylamine) glutathionatoplatinum (II). Iproplatin is promising for research of Thrombocytopenia and a wide range of cancers .
Cat. No.: HY-W771025
CAS No.: 2731163-22-5
Synonyms: Tetramethylene Iodide (stabilized with Copper CHIP)-13C4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
