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Cat. No.: HY-W763582A

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GelMA, 60% methacrylation

(Synonyms: Gelatin Methacryloyl, 60% methacrylation)

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GelMA (Gelatin Methacryloyl), 60% methacrylation, is a derivative obtained by the reaction of Methacrylic anhydride (MA) (HY-W017330) and gelatin. GelMA exhibits excellent biocompatibility, biodegradability, and moldability. GelMA can be photocrosslinked into hydrogels and can be used for research in regeneration of tissues, such as skin, tendon, bone, cartilage, blood vessel, and cardiovascular system. GelMA hydrogel also can be used for research on drug delivery, organ-on-a-chip, and biosensing.

For research use only. We do not sell to patients.

CAS No.: 2280018-77-9

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

GelMA, 60% methacrylation Chemical Structure

CAS No.: 2280018-77-9

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Sample (0.1mg)

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(In Japan)

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

In Vitro

GelMA, 60% methacrylation can be photocrosslinked with the photoinitiator LAP (HY-44076) to form a hydrogel that functions as a bioactive and biodegradable scaffold, providing structural support and cell-adhesion motifs for tissue cells^[1].
GelMA, 60% methacrylation can be formulated into hydrogels incorporated with chitosan microspheres (CM-SIN) for application in osteoarthritis research^[2].
GelMA, 60% methacrylation can be combined with poly(lactic-co-glycolic acid) (PLGA) (HY-B2247) microparticles to fabricate a composite microparticle system for drug delivery^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

GelMA, 60% methacrylation can be photocrosslinked into hydrogels that can promote both cutaneous tissue formation within two weeks and vascularization in a rat full-thickness wound model, thereby alleviating distal necrosis of random-pattern skin flaps^[4]^[5].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2280018-77-9
Appearance Solid
Color White to off-white
SMILES

[GelMA, 60% methacrylation]
Synonyms

Gelatin Methacryloyl, 60% methacrylation
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (Need ultrasonic)

View the Complete Stock Solution Preparation Table

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yun Piao, et al. "Biomedical applications of gelatin methacryloyl hydrogels." Engineered Regeneration 2 (2021): 47-56.

[2]. Chen P, et al. Intra-articular delivery of sinomenium encapsulated by chitosan microspheres and photo-crosslinked GelMA hydrogel ameliorates osteoarthritis by effectively regulating autophagy. Biomaterials. 2016 Mar;81:1-13. [Content Brief]

[3]. Y. Li, et al. Composite core-shell microparticles from microfluidics for synergistic drug delivery. Sci. China Mater., 60 (6) (2017), pp. 543-553.

[4]. Zhao X, et al. Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing. Biomaterials. 2017 Apr;122:34-47. [Content Brief]

[5]. X. Sun, et al. Electrospun photocrosslinkable hydrogel fibrous scaffolds for rapid in vivo vascularized skin flap regeneration. Adv. Funct. Mater., 27 (2) (2017).

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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