37 Results for "

CLDN18

" in MedChemExpress (MCE) Product Catalog:
Products (37)

37 Results for "CLDN18" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99350
CAS No.: 2413817-97-5
Synonyms: AMG 910; Anti-Human CD3xClaudin18 2

Target:  

CD3

Research Areas:  

Cancer

Gresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma .
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Cat. No.: HY-P991564
CAS No.: 3031170-61-0
Synonyms: IBI-343 antibody; HB37A6; TAK-921 Antibody

Target:  

ADC Antibodies Claudin

Research Areas:  

Cancer

Arcotatug (IBI-343 antibody) is a CLDN18.2 targeting humanized monoclonal antibody. Arcotatug can be used for synthesis of ADCs .
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Cat. No.: HY-P990742
CAS No.: 2762499-30-7
Synonyms: TJ-CD4B; ABL111; TJ033721

Target:  

TNF Receptor Claudin

Research Areas:  

Inflammation/Immunology Cancer

Givastomig (ABL111, TJ033721) is a bispecific antibody (BsAb) inhibitor. Givastomig can specifically binds to Claudin18.2 (CLDN 18.2) on the surface of cancer cells and 4-1BB (CD137, TNFRSF9) on the surface of activated T cells and natural killer (NK) cells. Givastomig is engineered to contain a single Fc-domain mutation (asparagine to alanine) to eliminate Fc-effector function. Givastomig-bound cell lines expressing a range of CLDN18.2 levels with high affinity and induced 4-1BB activation only in the context of CLDN18.2 binding. Givastomig can be used for the study of colon carcinoma .
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Cat. No.: HY-P991163
CAS No.: 2969220-04-8

Target:  

CD3 Claudin

Research Areas:  

Cancer

Tixentamig is a bispecific monoclonal antibody targeting human CD3 ε and CLDN18 (claudin 18). Tixentamig is promising for research of cancers .
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Cat. No.: HY-P991681
CAS No.: 3051701-97-1
Synonyms: ASP-2138

Target:  

Claudin CD3

Research Areas:  

Cancer

Emaretamig is a humanized IgG1κ monoclonal antibody inhibitor targeting CLDN18 and CD3E. Abdakibart can be used for cancers like gastric and pancreatic cancer research .
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Cat. No.: HY-P990946
CAS No.: 2823329-10-6
Synonyms: LM-102

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

HY-P990946 is an CLDN18-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991026
CAS No.: 2883771-43-3
Synonyms: AZD0901 Antibody; CM-G901 Antibody

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

HY-P991026 is an CLDN18-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-RS02768
Research Areas:  

Others

CLDN18 Human Pre-designed siRNA Set A contains three designed siRNAs for CLDN18 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991700
CAS No.: 3035406-55-1

Target:  

Claudin CD3

Research Areas:  

Cancer

Lumivatamig is an H-γ1_L-κ-scFvhl dimer-type bispecific antibody targeting CLDN18.2 & CD3E .
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Cat. No.: HY-RS18701
Research Areas:  

Others

Cldn18 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cldn18 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25188
Research Areas:  

Others

Cldn18 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cldn18 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991027
CAS No.: 2928515-36-8
Synonyms: PT-886

Target:  

CD47

Research Areas:  

Inflammation/Immunology

HY-P991027 is an CD47/CLDN18-targeting (H-γ1_L-κ)_(H-γ1_L-κ) type bispecific antibody .
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Cat. No.: HY-P991140
CAS No.: 3023285-05-1
Synonyms: SHR-1904 Antibody

Target:  

Claudin

Research Areas:  

Cancer

Garetatug is a humanized monoclonal antibody targeting human CLDN18 (claudin-18). Garetatug specifically binds to CLDN18, interfering with relevant cell signaling pathways and exerting antitumor activity .
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Cat. No.: HY-P991687
CAS No.: 3004869-54-6

Target:  

Claudin

Research Areas:  

Cancer

Gaspantatug is a humanized IgG1κ antibody targeting CLDN18.2. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991679
CAS No.: 3038456-00-4
Synonyms: TORL-2-307 antibody

Target:  

Claudin

Research Areas:  

Cancer

Elatatug is an anti-CLDN18 (claudin 18) IgG1κ type humanized antibody with antineoplastic activity. The recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P70701
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Claudin-18; CLDN18
Species:  
Source:  
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Cat. No.: HY-P70045
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuClaudin-18/CLDN18, His; Claudin-18; CLDN18
Species:  
Source:  
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Cat. No.: HY-P700404
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: Claudin-18; CLDN18.2; CLDN18
Species:  
Source:  
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Cat. No.: HY-P992467

Target:  

ADC Antibodies Claudin

Research Areas:  

Cancer

SOT102 Antibody is an IgG1 monoclonal antibody targeting CLDN18.2, and the antibody of ADC SOT102. SOT102 Antibody binds selectively to CLDN18.2, and promotes internalization. SOT102 Antibody can be used for the research of cancer [2].
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Cat. No.: HY-P992508
Synonyms: SX001

Target:  

Claudin

Research Areas:  

Cancer

SPX-101 (SX001) is a humanized monoclonal antibody targeting CLDN18.2. CLDN18.2 is only transiently expressed in the differentiated epithelial cells of the gastric mucosa and is hardly found in healthy tissues, thus having an extremely wide therapeutic window. SPX-101 can be used for the study of solid tumors.
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