2. Antibody-drug Conjugate/ADC Related
  3. ADC Antibody
  4. SOT102 Antibody

SOT102 Antibody is an IgG1 monoclonal antibody targeting CLDN18.2. SOT102 Antibody binds selectively to CLDN18.2, and promotes internalization. SOT102 Antibody can be used for the research of cancer[2].

For research use only. We do not sell to patients.

SOT102 Antibody

SOT102 Antibody Chemical Structure

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SOT102 Antibody Related Antibodies

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Description

SOT102 Antibody is an IgG1 monoclonal antibody targeting CLDN18.2. SOT102 Antibody binds selectively to CLDN18.2, and promotes internalization. SOT102 Antibody can be used for the research of cancer[1][2].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity

Human
In Vitro

SOT102 Antibody (SOT102.1 mAb) stimulates NK92 natural killer cells
to exhibit ADCC activity against the CLDN18.2 transfected pancreatic
adenocarcinoma cell line BxPC3 at an IC50 of approximately 0.5 nM[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

SOT102 Antibody Related Antibodies
Gene ID

51208  [NCBI]

Accession
Target

CLDN18.2
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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SOT102 Antibody Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SOT102 AntibodyADC Antibodytopoisomerase IIHEK293T cellsRNAPDX mouse modelsCLDN18.1PaTu 8988S cellscynomolgus monkeysDNACLDN18.2CDX mouse modelsInhibitorinhibitorinhibit

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SOT102 Antibody
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HY-P992467
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