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Cat. No.: HY-P992467

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SOT102 Antibody

SOT102 Antibody is an IgG1 monoclonal antibody targeting CLDN18.2, and the antibody of ADC SOT102. SOT102 Antibody binds selectively to CLDN18.2, and promotes internalization. SOT102 Antibody can be used for the research of cancer^[2]^.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

SOT102 Antibody Chemical Structure

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One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- In Vitro
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Isotype

Human IgG1 kappa

Recommend Isotype Controls

Human IgG1 kappa, Isotype Control

Species Reactivity

Human

In Vitro

SOT102 Antibody (SOT102.1 mAb) stimulates NK92 natural killer cells
to exhibit ADCC activity against the CLDN18.2 transfected pancreatic
adenocarcinoma cell line BxPC3 at an IC₅₀ of approximately 0.5 nM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gene ID

51208 [NCBI]

Accession

P56856

Target

CLDN18.2

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

Product Image

Application

ELISA, FACS, Functional assay

Chemical Information

Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Inhibitory Antibodies User Guide (603 KB)

References

[1]. SOT102 anti-Claudin 18.2 antibody-drug conjugate.

[2]. Valentová I, et al. SOT102, a novel CLDN18.2-targeting antibody-drug conjugate, exhibits strong therapeutic potential in solid tumors. BMC Cancer. Published online May 21, 2026. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- Description
- Isotype
- Recommend Isotype Controls
- Species Reactivity
- In Vitro
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Purity & Documentation
References

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MCE Japan Authorized Agent:

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SOT102 Antibody

PBS Buffer (1×)

DPBS Buffer (1×)

Cytotoxicity LDH Assay Kit

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

SOT102 Antibody Related Classifications

HY-P992467 Related Classifications