22 Results for "

CLDN18.2

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "CLDN18.2" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99350
CAS No.: 2413817-97-5
Synonyms: AMG 910; Anti-Human CD3xClaudin18 2

Target:  

CD3

Research Areas:  

Cancer

Gresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma .
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Cat. No.: HY-P991564
CAS No.: 3031170-61-0
Synonyms: IBI-343 antibody; HB37A6; TAK-921 Antibody

Target:  

ADC Antibodies Claudin

Research Areas:  

Cancer

Arcotatug (IBI-343 antibody) is a CLDN18.2 targeting humanized monoclonal antibody. Arcotatug can be used for synthesis of ADCs .
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Cat. No.: HY-P990742
CAS No.: 2762499-30-7
Synonyms: TJ-CD4B; ABL111; TJ033721

Target:  

TNF Receptor Claudin

Research Areas:  

Inflammation/Immunology Cancer

Givastomig (ABL111, TJ033721) is a bispecific antibody (BsAb) inhibitor. Givastomig can specifically binds to Claudin18.2 (CLDN 18.2) on the surface of cancer cells and 4-1BB (CD137, TNFRSF9) on the surface of activated T cells and natural killer (NK) cells. Givastomig is engineered to contain a single Fc-domain mutation (asparagine to alanine) to eliminate Fc-effector function. Givastomig-bound cell lines expressing a range of CLDN18.2 levels with high affinity and induced 4-1BB activation only in the context of CLDN18.2 binding. Givastomig can be used for the study of colon carcinoma .
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Cat. No.: HY-P991700
CAS No.: 3035406-55-1

Target:  

Claudin CD3

Research Areas:  

Cancer

Lumivatamig is an H-γ1_L-κ-scFvhl dimer-type bispecific antibody targeting CLDN18.2 & CD3E .
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Cat. No.: HY-P991687
CAS No.: 3004869-54-6

Target:  

Claudin

Research Areas:  

Cancer

Gaspantatug is a humanized IgG1κ antibody targeting CLDN18.2. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P700404
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: Claudin-18; CLDN18.2; CLDN18
Species:  
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Cat. No.: HY-P992467

Target:  

ADC Antibodies Claudin

Research Areas:  

Cancer

SOT102 Antibody is an IgG1 monoclonal antibody targeting CLDN18.2, and the antibody of ADC SOT102. SOT102 Antibody binds selectively to CLDN18.2, and promotes internalization. SOT102 Antibody can be used for the research of cancer [2].
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Cat. No.: HY-P704502
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: CLDN18; CLDN18.2; Claudin-18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
Species:  
Source:  
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Cat. No.: HY-P78368
Purity:  ≥ 95%, as determined by HPLC.
Synonyms: CLDN18; CLDN18.2; Claudin-18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
Species:  
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Cat. No.: HY-P700403
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: CLDN18; CLDN18.2; Claudin-18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
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Cat. No.: HY-P78105
Purity:  ≥ 95%, as determined by HPLC.
Synonyms: CLDN18; CLDN18.2; Claudin-18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
Species:  
Source:  
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Cat. No.: HY-P700440
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: CLDN18; CLDN18.2; Claudin-18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
Species:  
Source:  
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Cat. No.: HY-P704504
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CLDN18; CLDN18.2; Claudin-18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
Species:  
Source:  
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Cat. No.: HY-P705008
Synonyms: CLDN18; CLDN18.2; Claudin-18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
Species:  
Source:  
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Cat. No.: HY-P992508
Synonyms: SX001

Target:  

Claudin

Research Areas:  

Cancer

SPX-101 (SX001) is a humanized monoclonal antibody targeting CLDN18.2. CLDN18.2 is only transiently expressed in the differentiated epithelial cells of the gastric mucosa and is hardly found in healthy tissues, thus having an extremely wide therapeutic window. SPX-101 can be used for the study of solid tumors.
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Cat. No.: HY-P992412

Target:  

Claudin

Research Areas:  

Cancer

MIL93 is a humanized defucosylated IgG1 monoclonal antibody targeting Claudin18.2 (CLDN18.2) with enhanced antibody-dependent cellular cytotoxicity (ADCC) activity. MIL93 can be used for research on advanced solid tumors and gastric cancer. The recommended isotype control is human IgG1 kappa (HY-P99001) .
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Cat. No.: HY-P992355
Synonyms: GB7004-09hu15

Target:  

Claudin

Research Areas:  

Cancer

GB7004-09 (GB7004-09hu15) is a humanized monoclonal antibody against CLDN18.2. GB7004-09 can be used in cancer research .
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Cat. No.: HY-P992167

Target:  

Claudin

Research Areas:  

Cancer

AB011 is a recombinant humanized anti-CLDN18.2 IgG1 monoclonal antibody. AB011 exhibits synergistic effects with cytotoxic compounds in preclinical studies. AB011 can be used for research on advanced gastric/gastroesophageal junction adenocarcinoma and advanced pancreatic cancer .
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Cat. No.: HY-P992316

Target:  

Claudin ADC Antibodies

Research Areas:  

Cancer

ATG-022 Antibody is a humanized monoclonal antibody targeting Claudin 18.2 (CLDN 18.2). ATG-022 Antibody binds with VcMMAE (HY-15575) to form an Antibody-Drug Conjugate (ADC). ATG-022 Antibody can be used for the research of advanced/metastatic solid tumors and gastric cancer .
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Cat. No.: HY-P992487
ZL-1211 is an anti-CLDN18.2 monoclonal antibody. ZL-1211 exhibits enhanced binding affinity to CD16A. ZL-1211 induces ADCC-mediated cell lysis and triggers the production of IFNγ, TNFα and IL6. ZL-1211 promotes antibody-dependent cellular cytotoxicity. ZL-1211 exerts anti-tumor activity in a mouse xenograft model of gastric cancer. ZL-1211 can be used for the research of gastric cancer .
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