1 Result for "

CS47

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CS47" in MCE Product Catalog:

Cat. No.: HY-175806
CAS No.: 1372792-51-2
Research Areas:  

Cancer

CS47 is a Thioredoxin Reductase 1 (TRXR1) inhibitor and ferroptosis inducer. CS47 binds non-covalently to sites between the FAD and NADPH pockets of TRXR1. CS47 drives glutathione depletion, lipid reactive oxygen species accumulation, HMOX1-dependent iron overload, and selective cytotoxicity in lung cancer cells. CS47 can be used for the research of lung cancer .
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