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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
CSNK1A1
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "CSNK1A1" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
CSNK1-IN-2 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 44 nM. CSNK1-IN-2 can be used for the research of proliferative disorders .
1
1 Cited Publications
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CSNK1-IN-1 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 21 μM. CSNK1-IN-1 can be used for the research of proliferative disorders .
Synonyms: BRD5846
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BAY-888 is a selective CK1α/CSNK1A1 (casein kinase 1α) ATP-competitive inhibitor (IC50: 4 nM@10 μM ATP; 63 nM@1 mM ATP). BAY-888 blocks the negative regulation of p53 and other signaling pathways by CK1α, induces apoptosis and inhibits proliferation of tumor cells. BAY-888 has shown inhibitory efficacy against cancers such as acute myeloid leukemia (AML) in PRISM barcoded cell line screening and can mimic the effects of shRNA-mediated CK1α knockdown. BAY-888 is primarily used for the development of anticancer drugs for p53 wild-type tumors and for the study of the mechanisms of CK1α-related signaling pathways .
Cat. No.: HY-RS03245
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Research Areas:
CSNK1A1 Human Pre-designed siRNA Set A contains three designed siRNAs for CSNK1A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-175600
CAS No.: 1010099-35-0
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MI-2-80 is a molecular glue degrader. MI-2-80 induces proteins (such as IKZF1/3 and CSNK1A1) to bind to CRBN, promoting their ubiquitination and degradation .
Cat. No.: HY-RS17153
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Csnk1a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Csnk1a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23603
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Csnk1a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Csnk1a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS03248
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CSNK1G1 Human Pre-designed siRNA Set A contains three designed siRNAs for CSNK1G1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28516
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Csnk1g1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Csnk1g1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P72872
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CSNK1A1; CKIalpha; Casein Kinase 1 Alpha 1; Epididymis Secretory Sperm Binding Protein Li 77p; CK1; Non-Specific Serine/Threonine Protein Kinase; Casein Kinase I Isoform Alpha; Down-Regulated In Lung Cancer; CK1a; Casein Kinase 1, Alpha 1; CKIa; HEL-S-77p
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702668
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CSNK1A1; CKIalpha; Casein Kinase 1 Alpha 1; Epididymis Secretory Sperm Binding Protein Li 77p; CK1; Non-Specific Serine/Threonine Protein Kinase; Casein Kinase I Isoform Alpha; Down-Regulated In Lung Cancer; CK1a; Casein Kinase 1, Alpha 1; CKIa; HEL-S-77p
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-RS21999
Target:
Research Areas:
Csnk1g1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Csnk1g1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
