1 Result for "

DN 1289

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DN 1289" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-152142
CAS. Nr.: 3026597-15-6
Reinheit:  99.63%
Target:  

JNK

Forschungsgebiete:  

Neurological Disease

DN-1289 is an orally active and selective inhibitor of dual leucine zipper kinase (DLK; IC50=17 nM) and leucine zipper-bearing kinase (LZK; IC50=40 nM). DN-1289 results significant attenuation of optic nerve crush (ONC)-induced p-c-Jun in mice model. DN-1289 has excellent in vivo plasma half-life and blood-brain barrier permeability .
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