233 Results for "

DPPH radical scavenging

" in MedChemExpress (MCE) Product Catalog:
Products (233)

233 Results for "DPPH radical scavenging" in MCE Product Catalog:

51
51 Publications Verification
Cat. No.: HY-112053
CAS No.: 1898-66-4
Purity:  98.77%
Synonyms: 2,2-Diphenyl-1-picrylhydrazyl
DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .
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7
7 Cited Publications
Cat. No.: HY-B0377
CAS No.: 76824-35-6
Synonyms: MK-208
Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer .
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4
4 Cited Publications
Cat. No.: HY-N0448
CAS No.: 23513-15-7
10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC50 value of 10.47 μM against DPPH radical, an IC50 value of 1.68 μM against superoxide radical and an IC50 value of 1.35 μM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC50 of 12.1 μM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol can be used in research on various common cancers such as ovarian cancer and colon cancer, as well as colitis and neurodegenerative diseases .
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2
2 Cited Publications
Cat. No.: HY-N1417
CAS No.: 533-31-3
Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC50=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities . Anticancer activities .
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2
2 Cited Publications
Cat. No.: HY-N7931
CAS No.: 114420-66-5
Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity .
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2
2 Cited Publications
Cat. No.: HY-N2443
CAS No.: 22153-44-2
Tribuloside is a flavonoid and PDE4 inhibitor (IC50: 6 μM). Tribuloside exhibits antibacterial and antioxidant activities, capable of scavenging DPPH free radicals. Tribuloside also promotes melanogenesis. Tribuloside can be used in the research of hypopigmentary diseases, sun protection, and inflammatory diseases such as acute lung injury .
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1
1 Cited Publications
Cat. No.: HY-N6937
CAS No.: 158932-33-3
Synonyms: (R,R)-SDG; (R,R)-LGM2605
(R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is an isomer of Secoisolariciresinol diglucoside (HY-105008). (R,R)-Secoisolariciresinol diglucoside scavenges hydroxyl radicals, peroxyl radicals, and DPPH radicals. (R,R)-Secoisolariciresinol diglucoside reduces γ-ray-induced strand breaks in calf thymus DNA . (R,R)-Secoisolariciresinol diglucoside can be used in studies of oxidant-dependent inflammatory tissue injury .
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1
1 Cited Publications
Cat. No.: HY-N4111
CAS No.: 521-45-9
Wushanicaritin exhibits significant antioxidant activity (IC50=35.3 μM) in DPPH radical scavenging activity tests. Antitumor effects and anti-inflammatory property .
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1
1 Cited Publications
Cat. No.: HY-P1934A
CAS No.: 3705-26-8
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide . Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation . Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC50 of 24 µM in the DPPH assay .
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1
1 Cited Publications
Cat. No.: HY-N6829
CAS No.: 1245-15-4
Synonyms: Quercetin-​3,​3',​4',​7-​tetramethylether
Retusin (Quercetin-3,3',4',7-tetramethylether) is a tyrosinase inhibitor, with IC50 values of 50.9 μM and 51.8 μM against mushroom and intracellular tyrosinase, respectively. Retusin also acts as a free radical scavenger, melanogenesis inhibitor, anti-apoptosis agent, neuroprotective agent, antiemetic, antifungal agent, and antiviral agent. Retusin scavenges ABTS• + and DPPH• free radicals. Retusin can be used in studies related to hyperpigmentation, vomiting, Aspergillus niger infection, and COVID-19 infection .
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1
1 Cited Publications
Cat. No.: HY-124344
CAS No.: 116764-15-9
Purity:  98.90%
Avenanthramide C is an orally active polyphenolic compound that penetrates the blood-brain barrier. Avenanthramide C is derived from oats. Avenanthramide C inhibits NF-κB nuclear translocation and inhibits the phosphorylation of PI3K, PLCγ1, Lyn, Syk, and Akt. Avenanthramide C inhibits the expression and activity of MMP-9 and inhibits MAPK phosphorylation. Avenanthramide C scavenges DPPH radicals, reduces intracellular ROS, and inhibits pro-inflammatory cytokine release and adhesion molecule expression. Avenanthramide C inhibits cell degranulation. Avenanthramide C attenuates active systemic anaphylaxis and inhibits passive cutaneous anaphylaxis. Avenanthramide C ameliorates PHZ-induced blood stasis. Avenanthramide C inhibits neuroinflammation, restores long-term potentiation, and improves recognition and spatial memory in Alzheimer's disease models. Avenanthramide C can be used for research on allergic inflammation, thrombosis, atherosclerosis, and Alzheimer's disease .
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1
1 Cited Publications
Cat. No.: HY-N11077
CAS No.: 89886-30-6
Synonyms: 4,5-di-O-CQA
4,5-Di-O-caffeoylquinic acid (4,5-di-O-CQA) is a natural product with multiple activities including anti-inflammatory, antioxidant, and antibacterial properties. 4,5-Di-O-caffeoylquinic acid induces intracellular Ca 2+ influx, and inhibits hypoxia-induced COX-2 expression and cell migration via the TRPV1-mediated pathway. 4,5-Di-O-caffeoylquinic acid scavenges DPPH free radicals, inhibits Cu 2+-mediated LDL oxidation, and reduces the production of TBARS. 4,5-Di-O-caffeoylquinic acid promotes intracellular ATP production, inhibits Aβ42 aggregation and β-sheet conversion, and protects neuroblastoma cells. 4,5-Di-O-caffeoylquinic acid inhibits the growth of Bacillus shigae. 4,5-Di-O-caffeoylquinic acid can be used in studies related to atherosclerosis, Alzheimer's disease, and bacterial infections .
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Cat. No.: HY-N0521
CAS No.: 3371-27-5
(-)-Gallocatechin, an epimer of (-)-Epigallocatechin (EGC) (HY-N0225), is contained in various tea products. (-)-Gallocatechin demonstrates antioxidant activity in vitro, including inhibition of LDL oxidation and DPPH radical scavenging .
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Cat. No.: HY-W019885A
CAS No.: 7758-29-4
Synonyms: Sodium triphosphate pentabasic, 98%
Sodium tripolyphosphate (STPP), 98% is an inorganic, non-toxic polyphosphate crosslinker, inducer and enhancer. Sodium tripolyphosphate (STPP), 98% induces the formation of unique needle-like microcrystals in sodium alginate-chitosan composite films. Sodium tripolyphosphate (STPP), 98% enhances the DPPH free radical scavenging activity of sodium alginate-chitosan composite films .
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Cat. No.: HY-W001542
CAS No.: 3416-18-0
5-Hydroxyoxindole is a structural analog of uric acid for its antioxidant. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole is a product of partial metabolism of tryptophan involving conversion in the gut lumen of tryptophan to indole through the action of bacterial tryptophanase and tryptophan synthase. 5-Hydroxyoxindole is one of the main molecules responsible for the neurological symptoms of hepatic encephalopathy in rats. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders .
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Cat. No.: HY-112053R
CAS No.: 1898-66-4
Synonyms: 2,2-Diphenyl-1-picrylhydrazyl (Standard)
DPPH (Standard) is the analytical standard of DPPH. This product is intended for research and analytical applications. DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that can be used to measure the radical scavenging activity of antioxidants. The odd electron of nitrogen atom in DPPH is reduced by receiving a hydrogen atom from antioxidants to the corresponding hydrazine. DPPH method may be utilized in aqueous and nonpolar organic solvents and can be used to examine both hydrophilic and lipophilic antioxidants .
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Cat. No.: HY-N3985
CAS No.: 548-89-0
Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC50 value of 105.75 μg/ml .
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Cat. No.: HY-N3349
CAS No.: 14464-90-5
Lyoniresinol is a lignan isolated from the Tarenna attenuata with antioxidant activities. Lyoniresinol has radical scavenging activities against DPPH with an IC50 of 82.4 μM .
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Cat. No.: HY-N8194
CAS No.: 40039-49-4
Synonyms: Syringetin 3-O-β-D-glucoside
Syringetin-3-O-glucosid (Syringetin 3-O-β-D-glucoside), a flavonol glycoside, shows relatively weak DPPH and ABTS radical scavenging activity .
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Cat. No.: HY-N11173A
CAS No.: 618-67-7
trans-Melilotoside is a coumarin precursor and that can be isolated from Melilotus neapolitan. trans-Melilotoside exhibits antiparasitic and DPPH radical-scavenging activity. trans-Melilotoside can be used for the research of human african trypanosomiasis, chagas’ disease, malaria [1] [3].
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