Pedaliaceae Extract

Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia.

Harpagoside can be obtained by Harpagophytum procumbens, which has anti-inflammatory, anti-cancer, protective activity, and efficacy. Harpagoside has an inhibitory effect on COX-1 and COX-2 active, and suppresses NO production. Harpagoside inhibits HepG2 cell lipid polysaccharide, which is a protein that is expressed horizontally and selectively, and has anti-inflammatory and latent pain effects. Harpagoside has the ability to protect the body, and has a degenerative effect on the β-oxidation (Aβ).

Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC₅₀=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities. Anticancer activities.

Sesamolin, isolated from Sesamum indicum, has antioxidative activity, Sesamolin inhibits lipid peroxidation and shows neuroprotection effect. Sesamolinl potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression. Sesamolin is orally active.

Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a metabolite of Quercetin (HY-18085), can be isolated from Madagascarian Uncarina species. Quercetin 7-glucuronide can inhibit LDL oxidation.

Sesamin (Standard) is the analytical standard of Sesamin. This product is intended for research and analytical applications. Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia.

Quercetin 7-glucuronide (Standard) is the analytical standard of Quercetin 7-glucuronide (HY-W778608). This product is intended for research and analytical applications. Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a metabolite of Quercetin (HY-18085), can be isolated from Madagascarian Uncarina species. Quercetin 7-glucuronide can inhibit LDL oxidation.

Sesamolin (Standard) is the analytical standard of Sesamolin. This product is intended for research and analytical applications. Sesamolin, isolated from Sesamum indicum, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect. Sesamolin potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression.

Pedaliin is a bioactive component obtained from the ethanol extract of Sesame (Sesamum indicum L.) leaves (SLs). Pedaliin shows in vitro antioxidant and anti-colon cancer efficacy with radical scavenging activity and ferric reducing antioxidant power (FRAP).

Isocannflavin B (Caflanone) is an autophagy inducer that induces strong autophagic intracytoplasmic vacuolization in breast cancer cells. Isocannflavin B inhibits ACE2-mediated viral entry as well as SARS-CoV-2 PLpro and 3CLpro, and inhibits HCoV-OC43 in vitro. Isocannflavin B reduces Akt phosphorylation and p21^Cip1 expression in breast cancer cells. Isocannflavin B induces tumor cell apoptosis, autophagy, and cell cycle arrest, and inhibits cell proliferation. Isocannflavin B binds to the extracellular Ig-like domain of CSF1-R as a targeting ligand. Isocannflavin B can be used for research on breast cancer, viral infection, and Parkinson's disease.

Harpagophytum procumbens polysaccharide is a polysaccharide derived from Harpagophytum procumbens.

Sesamum indicum polysaccharide is a polysaccharide derived from Sesamum indicum.

Phenylmethyl O-β-D-glucopyranosyl-(1→3)-O-β-D-glucopyranoside (Compound 10) is a triglycoside compound. Phenylmethyl O-β-D-glucopyranosyl-(1→3)-O-β-D-glucopyranoside is isolated from the whole plant of sesame (Sesamum indicum).

Sesamol (Standard) is the analytical standard of Sesamol. This product is intended for research and analytical applications. Sesamol is a constituent of sesame oil. Sesamol shows a free radical scavenging activity. Sesamol shows an IC50=5.95±0.56 μg/mL in the DPPH assay. Anti-oxidant activities. Anticancer activities.

6-O-Syringoylajugol (compound 65) is a natural product that can be found in Verbacum spp.

Harpagoside (Standard) is the analytical standard of Harpagoside. This product is intended for research and analytical applications. Harpagoside can be obtained by Harpagophytum procumbens, which has anti-inflammatory, anti-cancer, protective activity, and efficacy. Harpagoside has an inhibitory effect on COX-1 and COX-2 active, and suppresses NO production. Harpagoside inhibits HepG2 cell lipid polysaccharide, which is a protein that is expressed horizontally and selectively, and has anti-inflammatory and latent pain effects. Harpagoside has the ability to protect the body, and has a degenerative effect on the β-oxidation (Aβ).