1. MAPK/ERK Pathway
    Apoptosis
  2. p38 MAPK
    JNK
    Caspase
  3. Sesamolin

Sesamolin 

Cat. No.: HY-N0809
Handling Instructions

Sesaminol, isolated from Justicia orbiculata, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect. Sesaminol potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression.

For research use only. We do not sell to patients.

Sesamolin Chemical Structure

Sesamolin Chemical Structure

CAS No. : 526-07-8

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Description

Sesaminol, isolated from Justicia orbiculata, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect. Sesaminol potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression[1][2][3][4].

Molecular Weight

370.35

Formula

C₂₀H₁₈O₇

CAS No.

526-07-8

SMILES

[H][[email protected]@]12[[email protected]@](CO[[email protected]@H]2C3=CC(OCO4)=C4C=C3)([H])[[email protected]](OC1)OC5=CC(OCO6)=C6C=C5

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Sesamolinp38 MAPKJNKCaspasec-Jun N-terminal kinaseInhibitorinhibitorinhibit

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