1 Result for "

Dimesna free acid

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Dimesna free acid" in MCE Product Catalog:

Cat. No.: HY-B1022A
CAS No.: 45127-11-5
Synonyms: BNP-7787 free acid
Target:  

Drug Derivative

Research Areas:  

Endocrinology Cancer

Dimesna (BNP-7787) free acid, the disulfide form of Mesna (HY-13679), is a platinum-related toxicity protective agent. Dimesna free acid converts to Mesna, which in turn inactivates toxic platinum substances. Dimesna free acid does not interfere with the antitumor activity of platinum compounds. Dimesna free acid does not affect the antiproliferative effects of Cisplatin (HY-17394) or Carboplatin (HY-17393). Dimesna free acid counteracts Cisplatin-induced nephrotoxicity. Dimesna free acid exerts selective protective effects on the kidneys. Dimesna free acid can be used in studies related to ovarian cancer and Cisplatin-induced nephrotoxicity .
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