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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
Discoidin domain receptor 1
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "Discoidin domain receptor 1" in MCE Product Catalog:
7
Target:
Research Areas:
7rh (DDR1-IN-2) is a potent inhibitor of discoidin domain receptor 1 (DDR1), with an IC50 of 13.1 nM, and also less potently inhibits DDR2, with an IC50 of 203 nM. 7rh is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
1
1 Cited Publications
Target:
Research Areas:
VU6015929 is a potent, selective and orally active dual discoidin domain receptor 1/2 (DDR1/2) inhibitor with IC50s of 4.67 nM and 7.39 nM, respectively. VU6015929 potently blocks collagen-induced DDR1 activation and collagen-IV production .
Target:
Research Areas:
DDR1-IN-4 (Compound 2.45) is a selective and potent Discoidin Domain Receptor 1 (DDR1) autophosphorylation inhibitor, with IC50 values of 29 nM and 1.9 μM for DDR1 and DDR2, respectively .
Target:
Research Areas:
DDR-TRK-1, a chemical probe, is a selective Discoidin Domain Receptor 1 (DDR1) inhibitor, with an IC50 value of 9.4 nM. DDR-TRK-1 also inhibits TRK family.
Cat. No.: HY-162540
Target:
Research Areas:
LLC355 is a discoidin domain receptor 1 (DDR1) ATTEC degrader with a DC50 of 150.8 nM. LLC355 induces DDR1 protein degradation via lysosome-mediated autophagy. LLC355 inhibits the tumorigenicity, migration and invasion abilities of cancer cells, and induces apoptosis. LLC355 is applicable to research related to non-small cell lung cancer and pancreatic cancer .
Cat. No.: HY-NP131
Research Areas:
Recombinant Humanized Type III Collagen 10.4kDa is a novel biomaterial that have anticancer effects. Recombinant Humanized Type III Collagen 10.4kDa activates discoidin domain receptor 1 (DDR1), and thus inhibits autophagy, proliferation, and migration of cancer cells, and induces apoptosis .
Cat. No.: HY-173284
CAS No.: 639089-54-6
Target:
Research Areas:
DDR1-IN-11 (Compound 4) is an inhibitor of Discoidin domain receptor 1 (DDR1) with an IC50 of 46.16 nM. DDR1-IN-11 can achieve an inhibition rate of 99.86% against Z-138 cells at a concentration of 10 μM, and it can be used in the research of acute myeloid leukemia (AML) .
Cat. No.: HY-P85119
Synonyms: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE; Epithelial Discoidin domain-containing receptor 1; Epithelial Discoidin domain receptor 1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2;
Cat. No.: HY-P705128
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein-Tyrosine Kinase; RTK6; Neuroepithelial Tyrosine Kinase; Epithelial Discoidin domain-Containing receptor 1; Discoidin domain receptor DDR1e; CD167 Antigen-Like Family Member A; Discoidin domain receptor DDR1d; Tyrosine Kinase DDR; Protein-Tyrosine Kinase 3A; CD167; CD167a Antigen; Discoidin receptor Tyrosine Kinase; MCK-10; Protein-Tyrosine Kinase RTK-6; MCK10; Mammary Carcinoma Kinase 10; TRK E; Tyrosine-Protein Kinase CAK; PTK3; Cell Adhesion Kinase; DDR; Discoidin domain receptor Tyrosine Kinase 1; TRKE
Species:
Human
Source:
HEK293
Cat. No.: HY-P706032
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein-Tyrosine Kinase; RTK6; Neuroepithelial Tyrosine Kinase; Epithelial Discoidin domain-Containing receptor 1; Discoidin domain receptor DDR1e; CD167 Antigen-Like Family Member A; Discoidin domain receptor DDR1d; Tyrosine Kinase DDR; Protein-Tyrosine Kinase 3A; CD167; CD167a Antigen; Discoidin receptor Tyrosine Kinase; MCK-10; Protein-Tyrosine Kinase RTK-6; MCK10; Mammary Carcinoma Kinase 10; TRK E; Tyrosine-Protein Kinase CAK; PTK3; Cell Adhesion Kinase; DDR; Discoidin domain receptor Tyrosine Kinase 1; TRKE
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P75299
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein
Species:
Rat
Source:
HEK293
Cat. No.: HY-P75302
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P75305
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein
Species:
Human
Source:
HEK293
Cat. No.: HY-P77639
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P704093
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein
Species:
Human
Source:
HEK293
Cat. No.: HY-P75300
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein
Species:
Rat
Source:
HEK293
Cat. No.: HY-P75303
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P705804
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P75301
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P75304
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: DDR1; HGK2; Prev. EDDR1; Neurotrophic Tyrosine Kinase, receptor, Type 4; Prev. NTRK4; Discoidin domain receptor Family, Member 1; Prev. PTK3A; Epithelial Discoidin domain receptor 1; Prev. CAK; PTK3A Protein Tyrosine Kinase 3A; Prev. NEP; receptor Protein
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
