10 Results for "

E26

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "E26" in MCE Product Catalog:

9
9 Cited Publications
Cat. No.: HY-122903
CAS No.: 1903783-48-1
Purity:  99.84%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor . TK216 directly binds EWS-FLI1 and inhibits EWS-FLI1 protein interactions. TK216 blocks the binding between EWS-FLI1 and RNA helicase A. TK216 has anticancer activity .
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1
1 Cited Publications
Cat. No.: HY-P70292
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ETS1; FLJ10768; Prev. EWSR2; V-Ets Avian Erythroblastosis Virus E2 Oncogene Homolog 1; ETS-1; ETS1 Protein; Avian Erythroblastosis Virus E26 (V-Ets) Oncogene Homolog-1; Ets Protein; V-Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1; C-Ets-1; Prote
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-122903B
CAS No.: 1903783-77-6
Purity:  99.91%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

(+)-TK216 is an enantiomer of TK216 (HY-122903). TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor .
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Cat. No.: HY-122903S
CAS No.: 3034816-36-6
TK216-d4 is the deuterium labeled TK216 (HY-122903). TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor . TK216 directly binds EWS-FLI1 and inhibits EWS-FLI1 protein interactions. TK216 blocks the binding between EWS-FLI1 and RNA helicase A. TK216 has anticancer activity .
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Cat. No.: HY-122903A
CAS No.: 1903783-78-7
Purity:  99.45%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

(-)-TK216 is an enantiomer of TK216 (HY-122903). TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor. (-)-TK216 has anti-cancer activity .
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Cat. No.: HY-P992024

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

SK48-E26 is a human interleukin-1β (IL-1β) inhibitor, with a IC50 of 400 pM against human IL-1β, a IC50 of 185 pM against cynomolgus monkey IL-1β, and a Ka value ranging from 0.048 nM to 3 nM for human IL-1β. SK48-E26 binds to the conformational epitope of human IL-1β spanning amino acid residues 95-101, and blocks the biological activity of IL-1β. SK48-E26 can be used in research related to IL-1β-mediated inflammatory diseases and osteoarthritis .
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Cat. No.: HY-154858A
CAS No.: 15575-14-1
Synonyms: (2E,6E,10E,14E,18E,22E,26E,30E,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaen-1-ol
Undecaprenol is a prenol .
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Cat. No.: HY-117840
CAS No.: 134887-78-8
Altromycin F is an anthraquinone-derived antibiotic produced by the actinomycete AB 1246E-26 isolated from a South African bush soil. Altromycin F has antibacterial activity against Gram-positive bacteria, particularly Streptococcus and Staphylococcus, with a microbial inhibitory concentration (MIC) ranging from 0.2-3.12 μg/mL .
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Cat. No.: HY-173163
CAS No.: 2811663-45-1
Target:  

Bacterial

Research Areas:  

Infection

(E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) (Compound 4a) is a Gram-negative outer membrane permeabilizer with synergistic antibacterial activity through the blockage on LptA/LptC interaction via targeting Met47 in LptA. (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) potentiates pol B against both wild-typed and MDR A. baumannii and E. coli strains. (E)-2,6-Di-tert-butyl-4-(4-(diethylamino)styryl)pyrylium (trifluoromethanesulfonate) can be used as antibiotic adjuvants against MDR Gram-negative bacteria .
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Cat. No.: HY-P71733
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERG; V-Ets Erythroblastosis Virus E26 Oncogene Homolog; ETS Transcription Factor ERG; TMPRSS2-ERG Prostate Cancer Specific Isoform 1; Erg-3; TMPRSS2-ERG Prostate Cancer Specific; P55; ERG, ETS Transcription Factor; Transcriptional Regulator ERG (Transform
Species:  
Human
Source:  
P. pastoris
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