1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. (+)-TK216

(+)-TK216 

Cat. No.: HY-122903B
Handling Instructions

(+)-TK216 is an enantiomer of TK216 (HY-122903). TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor.

For research use only. We do not sell to patients.

(+)-TK216 Chemical Structure

(+)-TK216 Chemical Structure

CAS No. : 1903783-77-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 495 In-stock
Estimated Time of Arrival: December 31
5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
10 mg USD 800 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2550 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3800 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

(+)-TK216 is an enantiomer of TK216 (HY-122903). TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor[1][2].

In Vitro

(+)-TK216 (compound 13; for 3 days) has an IC50>5 μM in SKES cells (Ewing Sarcoma cell line)[1].
(+)-TK216 has T1/2s of 103.4 mins, 3.6 mins, 26.6 mins and 8.4 mins for human, rat, mouse, dog liver microsomes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

376.23

Formula

C₁₉H₁₅Cl₂NO₃

CAS No.

1903783-77-6

SMILES

O=C1NC2=C(C(Cl)=CC=C2Cl)C1(CC(C3=CC=C(C4CC4)C=C3)=O)O.[Rotation (+)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

(+)-TK216DNA/RNA SynthesisSKESEwingSarcomaInhibitorinhibitorinhibit

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(+)-TK216
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HY-122903B
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