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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
EIF4A2
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "EIF4A2" in MCE Product Catalog:
Research Areas:
eIF4E-IN-2 is a potent inhibitor of eukaryotic initiation factor 4e (eIF4e) with an IC50 of 13 nM. eIF4E-IN-2 inhibits MDA-MB-361 cells proliferation. eIF4E-IN-2 can be used for the study of breast cancer .
Cat. No.: HY-RS04271
Target:
Research Areas:
EIF4A2 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS21121
Target:
Research Areas:
Eif4a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27640
Target:
Research Areas:
Eif4a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif4a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-129768
CAS No.: 2368900-33-6
Research Areas:
CMLD012072 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012072 can induce RNA clamping of eIF4A1 and eIF4A2 and possess potent anti-neoplastic activity .
Cat. No.: HY-176843
CAS No.: 3083974-69-7
Research Areas:
eIF4A-IN-2 (Compound 93) is an Eukaryotic translation initiation factor 4A (eIF4A) inhibitor. eIF4A-IN-2 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-P700526
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EIF4A2; ATP-Dependent RNA Helicase EIF4A-2; Prev. EIF4F; EIF4A-II; DDX2B; Eukaryotic Translation Initiation Factor 4A, Isoform 2; BM-010; ATP-Dependent RNA Helicase; EIF4A; RNA Helicase; Eukaryotic Initiation Factor 4A-II; NEDHSS; Eukaryotic Translation I
Species:
Human
Source:
E. coli
Cat. No.: HY-173172
CAS No.: 3076503-34-6
Research Areas:
MG-002 is an orally active eIF4A1 and eIF4A2 inhibitor with a human eIF4A1 IC50 of 43 nM. MG-002 prevents competent ribosome recruitment to mRNA, inhibits cap-dependent mRNA translation, and engages eIF4A2 via the same RNA clamping mechanism to inhibit mRNA translation. MG-002 induces G2/M cell cycle delay, induces apoptosis, suppresses synthesis of c-MYC and cyclin D1, and shows minimal overt toxicity in mice. MG-002 inhibits primary triple-negative breast cancer tumor growth, attenuates metastatic spread, and enhances anti-neoplastic activity of Doxorubicin (HY-15142A) in pre-clinical models .
Cat. No.: HY-P87157
Synonyms: ATP dependent RNA helicase EIF4A 2 antibody; ATP-dependent RNA helicase EIF4A-2 antibody; BM-010 antibody; DDX2B antibody; EIF 4A II antibody; EIF-4A-II antibody; EIF4A antibody; EIF4A II antibody; EIF4A-II antibody; EIF4A2 antibody; ATP dependent RNA helicase EIF4A 2 antibody; ATP-dependent RNA helicase EIF4A-2 antibody; BM-010 antibody; DDX2B antibody; EIF 4A II antibody; EIF-4A-II antibody; EIF4A antibody; EIF4A II antibody; EIF4A-II antibody; EIF4A2 antibody; EIF4F antibody; Eukaryotic initiation factor 4A II antibody; Eukaryotic initiation factor 4A-II antibody; eukaryotic translation initiation factor 4A isoform 2 antibody; Eukaryotic translation initiation factor 4A2 antibody; IF4A2_HUMAN antibody; N-terminally processed antibody;
Cat. No.: HY-RS17097
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Research Areas:
Eif4b Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4b gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04275
Target:
Research Areas:
EIF4E2 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4E2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04278
Target:
Research Areas:
EIF4EBP2 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4EBP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04282
Target:
Research Areas:
EIF4G2 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4G2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20664
Target:
Research Areas:
Eif4ebp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27175
Target:
Research Areas:
Eif4ebp2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eif4ebp2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
