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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
ESIPT
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "ESIPT" in MCE Product Catalog:
Cat. No.: HY-W140203
CAS No.: 2963-66-8
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Research Areas:
2-(2′-Hydroxyphenyl) benzimidazole is the most extensively studied excited-state intramolecular proton transfer (ESIPT) molecule, exhibiting normal and tautomer emissions. 2-(2′-Hydroxyphenyl) benzimidazole has been applied as a fluorescent probe in various systems .
Cat. No.: HY-N16571
CAS No.: 65602-55-3
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Target:
Cat. No.: HY-D2286
Cat. No.: HY-D3067
Target:
Research Areas:
ASSI-Leu is a novel AIE fluorescent probe based on an asymmetric tetraaryl imidazole skeleton, which can be used for ratiometric imaging detection of endogenous leucine aminopeptidase. ASSI-Leu contains an L-leucine-based recognition group that blocks the excited-state intramolecular proton transfer (ESIPT) in its 2-(2'-hydroxyphenyl) benzothiazole (HBT) skeleton, thereby generating an enol-form emission signal at Ex/Em = 365/417 nm. ASSI-Leu undergoes cleavage of the L-leucine group mediated by LAP to form ASSI-OH, which further activates aggregation-induced emission (AIE) and ESIPT, generating a keto-form emission signal at Ex/Em = 365/554 nm and producing a ratiometric fluorescent signal. ASSI-Leu enables real-time tracking of LAP in cancer cells and zebrafish models .\n
Cat. No.: HY-D3082
CAS No.: 2222720-58-1
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Probe L is an AIE-based dual-sensing fluorescent probe for the detection of Zn 2+ and single-stranded DNA (ssDNA). Coordination of Probe L with Zn 2+ restricts intramolecular rotation and triggers ESIPT, turning on fluorescence at 490 nm. Upon further binding of the Probe L-Zn 2+ complex to ssDNA, enhanced emission is generated at 550 nm. Ex/Em = 365/490 nm (Zn 2+); Ex/Em = 365/550 nm (ssDNA) .
Cat. No.: HY-D3150
CAS No.: 905306-19-6
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di-SFA is a fluorescent probe used to measure transmembrane potential (Vm) across the plasma membrane. di-SFA contains a 3-hydroxychromone fluorophore that undergoes excited-state intramolecular proton transfer (ESIPT), producing dual emission from the normal (N*) and tautomeric (T*) states. di-SFA inserts deeply into the hydrophobic region of lipid bilayers. The sulfonate groups give di-SFA a double negative charge in aqueous media. Ratiometric measurements are performed in lipid vesicles using Ex/Em = 450/527 nm and Ex/Em = 450/605 nm.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
