34 Results for "

FOLR1

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "FOLR1" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-132258A
CAS No.: 1453084-37-1
Purity:  99.71%
Synonyms: IMGN853 (solution)
Research Areas:  

Cancer

Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A, and the drug-linker conjugate for ADC is sulfo-SPDB-DM4 (HY-101141). Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage [1].
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2
2 Cited Publications
Cat. No.: HY-P99225
CAS No.: 1453084-36-0
Synonyms: M9346A

Research Areas:  

Cancer

Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research [1] .
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2
2 Cited Publications
Cat. No.: HY-P99225A
CAS No.: 1453084-36-0
Synonyms: M9346A (powder)

Research Areas:  

Cancer

Mirvetuximab (M9346A) (powder) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab (powder) is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research [1] .
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Cat. No.: HY-P990941
CAS No.: 2853518-94-0
Synonyms: F131; GEN1184 antibody

Target:  

Antifolate

Research Areas:  

Inflammation/Immunology

Rinatabart (F131) is an IgG1-κ human antibody targeting FOLR1, with its corresponding isotype control being Human IgG1 kappa, Isotype Control (HY-P99001). The Fc region of Rinatabart is engineered to reduce antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) activities. The KD values of Rinatabart binding to human FOLR1 in two sets of BLI assays are 1.528 nM and 5.296 nM, respectively. Rinatabart shows significantly lower affinity for FOLR2 and mouse FOLR1, and no reliable specific binding to FOLR3 and rat FOLR1. Rinatabart can be used in studies of FOLR1 targeting and antibody-drug conjugates [1].
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Cat. No.: HY-P990687

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Luveltamab is an anti-FOLR1 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-RS05029
Research Areas:  

Others

FOLR1 Human Pre-designed siRNA Set A contains three designed siRNAs for FOLR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16758
Research Areas:  

Others

Folr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Folr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23197
Research Areas:  

Others

Folr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Folr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991695
CAS No.: 3035565-36-4

Target:  

Folate Receptor (FR)

Research Areas:  

Cancer

Lazatatug is an anti-FOLR1 IgEκ type humanized antibody with antineoplastic activity [1].
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Cat. No.: HY-P990417

Target:  

Antifolate

Research Areas:  

Inflammation/Immunology

Anti-FOLR1/FRA Antibody is a humanized antibody expressed in CHO cells, targeting FOLR1/FRA. The Anti-FOLR1/FRA Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.46 kDa. The isotype control for the Anti-FOLR1/FRA Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990935
CAS No.: 2779564-38-2
Synonyms: IMGN-151 Antibody

Target:  

Antifolate

Research Areas:  

Inflammation/Immunology

HY-P990935 is an FOLR1-targeting half-IG G1 -κ/(scFv -κ-heavy) -h-CH2-CH3 type chimeric antibody [1].
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Cat. No.: HY-P992004
Synonyms: RA15-7, HuRA15-7Acc

Target:  

Folate Receptor (FR)

Research Areas:  

Cancer

KHK2805 (RA15-7) is a humanized antibody against folate receptor α (FOLR1), with a Kd of 0.647 nM for human FOLR1. KHK2805 binds to a unique epitope of FOLR1 and mediates antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity against FOLR1-expressing cells. KHK2805 exhibits cytotoxicity against both ovarian cancer cells and Platinum (HY-W096169D)-resistant ovarian cancer cells. KHK2805 can be used for the research of tumors such as ovarian cancer [1].
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Cat. No.: HY-P78871
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FOLR-1; FBP; FOLR
Species:  
Source:  
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Cat. No.: HY-P701278
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FOLR-1; FBP; FOLR; FRα
Species:  
Source:  
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Cat. No.: HY-P705524
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FOLR-1; FBP; FOLR; FRα
Species:  
Source:  
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Cat. No.: HY-P78445
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FOLR; FOLR1; FBP; Folbp1; KB cells FBP; MOv18
Species:  
Source:  
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Cat. No.: HY-P75775
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Folate receptor alpha; FR-alpha; FBP; FOLR1; FOLR
Species:  
Rat
Source:  
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Cat. No.: HY-P75776
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Folate receptor alpha; FR-alpha; FBP; FOLR1; FOLR
Species:  
Rat
Source:  
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Cat. No.: HY-P76937
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Folate receptor alpha; FR-alpha; FBP; FOLR1; FOLR
Species:  
Source:  
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Cat. No.: HY-P76936
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Folate receptor alpha; FR-alpha; FBP; FOLR1; FOLR
Species:  
Source:  
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