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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
FOSL1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "FOSL1" in MCE Product Catalog:
Cat. No.: HY-162723
FOSL1 degrader 1 is a FOSL1 PROTAC degrader with a DC50 of 2.3 μM. FOSL1 degrader 1 induces proteasomal degradation of FOSL1. FOSL1 degrader 1 eliminates cancer stem cells in head and neck squamous cell carcinoma. FOSL1 degrader 1 suppresses head and neck squamous cell carcinoma tumorigenesis. FOSL1 degrader 1 can be used for the research of head and neck squamous cell carcinoma [1].
Cat. No.: HY-RS05034
Target:
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FOSL1 Human Pre-designed siRNA Set A contains three designed siRNAs for FOSL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W019901B
CAS No.: 7778-18-9
Synonyms: Gypsum ustum (97%)
Cat. No.: HY-RS24539
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Research Areas:
Fosl1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fosl1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18064
Target:
Research Areas:
Fosl1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fosl1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-190512
CAS No.: 3101626-89-2
Research Areas:
Copper chelator is a copper chelator with anticancer activity. Copper chelator inhibits mitochondrial complex IV through copper depletion, triggering ROS/RNS stress and activating ERK/JNK/p38/AMPK, while suppressing the NRF2 antioxidant response through Keap1 upregulation. Copper chelator induces paraptosis-like death, endoplasmic reticulum stress, mitochondrial dysfunction, and ATP depletion, and inhibits cancer cell invasion and metastasis by downregulating MMP and FOSL1. Copper chelator chelates Cu (I) to form Cu complexes and releases NO with glutathione. Copper chelator inhibits the proliferation of Cu-sensitive melanoma cells and organoids as well as melanoma tumor growth in mice. Copper chelator can be used for research on melanoma [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
