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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
GPR132
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "GPR132" in MCE Product Catalog:
5
5 Cited Publications
Target:
Research Areas:
ONC212, a fluorinated-ONC201 analogue, is a promising anti-cancer agent and also a selective agonist of GPR132. ONC212 also induces apoptosis .
1
1 Cited Publications
Synonyms: GPR132 antagonist 1
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NOX-6-18 (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 μM. NOX-6-18 has promote insulin secretion activity with an EC50 value of 0.7 μM .
Cat. No.: HY-163763
CAS No.: 1608784-68-4
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T-10418 is a potent and highly selective G2A/GPR132 agonist. T-10418 has an EC50 of 0.82 μM for human G2A activation. T-10418 has good water solubility, metabolic stability, and pharmacokinetic properties. T-10418 can be used for the research of various diseases such as neuropathic pain, acute myeloid leukemia, and inflammation .
Cat. No.: HY-RS17514
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Gpr132 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpr132 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-157189A
Synonyms: GPR132 antagonist 1 (dihydrocholide)
Target:
Research Areas:
NOX-6-18 (dihydrocholide) (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 μM. NOX-6-18 (dihydrocholide) has promote insulin secretion activity with an EC50 value of 0.7 μM .
Cat. No.: HY-RS05656
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GPR132 Human Pre-designed siRNA Set A contains three designed siRNAs for GPR132 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-184442
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Research Areas:
GPR132 antagonist-2 is a G2A (GPR132) antagonist with an IC50 of 0.69 μM. GPR132 antagonist-2 exerts weak stabilizing effects on the bromodomain of BRD2 and exhibits selectivity for non-olfactory GPCRs. GPR132 antagonist-2 inhibits G2A activation, blocks downstream inositol monophosphate accumulation, reverses G2A-mediated TRPV1 sensitization, suppresses 9-HODE-mediated capsaicin-induced TRPV1 responses, and activates FPR3. GPR132 antagonist-2 can be used in studies related to neuropathic pain .
Cat. No.: HY-RS23971
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Gpr132 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gpr132 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-119494
CAS No.: 193825-78-4
Category:
Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-139938
CAS No.: 90693-45-1
Synonyms: 11,12-EET methyl ester; (±)11,12-EpETrE methyl ester
Target:
Research Areas:
(±)11(12)-EET methyl ester (11,12-EET-methyl ester) is a methylated derivative of 11,12-epoxyeicosatrienoic acid (11,12-EET) (HY-130494). (±)11(12)-EET methyl ester cannot induce β-arrestin recruitment of the G protein-coupled receptor GPR132. (±)11(12)-EET methyl ester fails to enhance the expression of hematopoietic stem and progenitor cell (HSPC) markers. (±)11(12)-EET methyl ester can be used as a negative control molecule to study the structure-function relationship of 11,12-EET, facilitating the analysis of the role of the oxygenated fatty acid-GPR132 signaling axis in hematopoiesis .
Cat. No.: HY-139938S
Synonyms: 11,12-EET methyl ester-d11; (±)11,12-EpETrE methyl ester-d11
Cat. No.: HY-179551S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
