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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
Gabapentin
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "Gabapentin" in MCE Product Catalog:
16
16 Cited Publications
Referencia número: HY-A0057
No. CAS: 60142-96-3
Target:
Áreas de investigación:
Gabapentin is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin inhibits neuronal Ca 2+ influx and reduction of neurotransmitter release. Gabapentin is a GABA analog that can be used to relieve neuropathic pain .
16
16 Cited Publications
Referencia número: HY-A0057A
No. CAS: 60142-95-2
Target:
Áreas de investigación:
Gabapentin hydrochloride is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca 2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain .
Referencia número: HY-142240
No. CAS: 2209104-84-5
Synonyms: HSK16149
Target:
Áreas de investigación:
Crisugabalin is an orally active, selective ligand for the α2δ subunit of voltage-gated calcium channels, with a target IC50 of 3.96 nM in rats. Crisugabalin inhibits the binding of [ 3H]gabapentin to the α2δ subunit, reduces calcium influx, decreases neuronal excitability, and impairs nociceptive transmission. Crisugabalin alleviates mechanical allodynia, neuropathic pain and inflammatory pain in rats, and reduces phase II pain behaviors. Crisugabalin can be used in research related to chronic pain, neuropathic pain, diabetic neuropathy, fibromyalgia, inflammatory pain, diabetic peripheral neuropathy and postherpetic neuralgia.
Referencia número: HY-16216
No. CAS: 478296-72-9
Synonyms: XP-13512
Target:
Áreas de investigación:
Gabapentin enacarbil (XP-13512) is a prodrug of Gabapentin (HY-A0057) designed to be absorbed throughout the intestine by high-capacity nutrient transporters. Gabapentin is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin enacarbil can be used for the study of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN) .
Referencia número: HY-W016194
No. CAS: 67950-95-2
Synonyms: 1-Carboxycyclohexaneacetic acid; Gabapentin Impurity E; Gabapentin Related Compound E
Target:
Áreas de investigación:
1-(Carboxymethyl) cyclohexanecarboxylic acid (1-Carboxycyclohexaneacetic acid; Gabapentin Impurity E; Gabapentin Related Compound E) is a succinic acid and a potential impurity in the synthesis of Gabapentin (HY-A0057), and it can be used in studies related to organic synthesis .
Referencia número: HY-A0057S
No. CAS: 1185039-20-6
Referencia número: HY-A0057R
No. CAS: 60142-96-3
Target:
Áreas de investigación:
Gabapentin (Standard) is the analytical standard of Gabapentin. This product is intended for research and analytical applications. Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin is a GABA analog that can be used to relieve neuropathic pain .
Referencia número: HY-A0057AS
No. CAS: 1432061-73-8
Referencia número: HY-W721517
No. CAS: 1126623-20-8
Referencia número: HY-A0057AS2
Referencia número: HY-16216R
No. CAS: 478296-72-9
Synonyms: XP-13512 (Standard)
Target:
Áreas de investigación:
Gabapentin enacarbil (Standard) is the analytical standard of Gabapentin enacarbil. This product is intended for research and analytical applications. Gabapentin enacarbil (XP-13512) is a prodrug of Gabapentin (HY-A0057) designed to be absorbed throughout the intestine by high-capacity nutrient transporters. Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin enacarbil can be used for the study of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN) .
Referencia número: HY-W016194R
No. CAS: 67950-95-2
Synonyms: 1-Carboxycyclohexaneacetic acid (Standard); Gabapentin Impurity E (Standard); Gabapentin Related Compound E (Standard)
Target:
Áreas de investigación:
1-(Carboxymethyl)cyclohexanecarboxylic acid (Standard) (1-Carboxycyclohexaneacetic acid (Standard); Gabapentin Impurity E (Standard); Gabapentin Related Compound E (Standard)) is the analytical standard of 1-(Carboxymethyl)cyclohexanecarboxylic acid (HY-W016194). This product is intended for research and analytical applications. 1-(Carboxymethyl) cyclohexanecarboxylic acid (1-Carboxycyclohexaneacetic acid; Gabapentin Impurity E; Gabapentin Related Compound E) is a succinic acid and a potential impurity in the synthesis of Gabapentin (HY-A0057), and it can be used in studies related to organic synthesis .
Referencia número: HY-W744271
Synonyms: Gabapentin lactam-d6
Referencia número: HY-135774R
No. CAS: 152831-00-0
Áreas de investigación:
1-(Carboxymethyl)cyclohexanecarboxylic acid (Standard) is the analytical standard of 1-(Carboxymethyl)cyclohexanecarboxylic acid. This product is intended for research and analytical applications. 1-(Carboxymethyl)cyclohexanecarboxylic acid (1-Carboxycyclohexaneacetic acid; Gabapentin Impurity E) is a potential impurity in commercial preparations of the antiepileptic agent Gabapentin (HY-A0057). It is also used as a precursor for the synthesis of a serotonin (5-HT) receptor subtype 5-HT2A antagonist.
Referencia número: HY-W013814
No. CAS: 1076198-17-8
Synonyms: Gabapentin impurity D
Target:
Áreas de investigación:
Gabapentin acid impurity 1 (Gabapentin impurity D) is an impurity of Gabapentin acid.
Referencia número: HY-Z8265
No. CAS: 1500558-49-5
Synonyms: Gabapentin impurity G
Target:
Áreas de investigación:
Gabapentin acid impurity 2 (Gabapentin impurity G) is an impurity of Gabapentin acid.
Referencia número: HY-CE01790
Synonyms: Gabapentin-coenzyme A
Target:
Áreas de investigación:
Gabapentin-CoA (Gabapentin-coenzyme A) is a coenzyme A derivative .
Referencia número: HY-A0057AR
No. CAS: 60142-95-2
Target:
Áreas de investigación:
Gabapentin (hydrochloride) (Standard) is the analytical standard of Gabapentin (hydrochloride). This product is intended for research and analytical applications. Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain .
Referencia número: HY-135228
No. CAS: 68312-88-9
Target:
Áreas de investigación:
GZ4 is a calcium current inhibitor with direct inhibitory activity on cell surface channels. GZ4 inhibition reverses mechanical hyperalgesia/hyperalgesia in a spinal nerve ligation-induced neuropathic pain model. The mechanism of action of GZ4 is similar to that of gabapentin, but the time course of its biological effects is more rapid, indicating that GZ4 can directly inhibit calcium channel currents .
Referencia número: HY-W039179
No. CAS: 64744-50-9
Target:
Áreas de investigación:
Gabapentin acid impurity 4 is an impurity of Gabapentin acid.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
