Search Result
Results for "
Gram-negative aerobic bacteria
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
10
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-B1369A
-
|
N-Formimidoyl thienamycin; MK0787
|
Antibiotic
Bacterial
|
Infection
|
|
Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
-
- HY-B1369
-
|
N-Formimidoyl thienamycin monohydrate; MK0787 monohydrate
|
Antibiotic
Bacterial
|
Infection
|
|
Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
-
- HY-B0593
-
Ceftazidime
Maximum Cited Publications
42 Publications Verification
GR20263
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
|
-
-
- HY-B0510
-
|
|
Antifolate
Bacterial
Antibiotic
Influenza Virus
|
Infection
Cancer
|
|
Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
|
-
-
- HY-B0479
-
|
Thiophenicol; Dextrosulphenidol
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
-
- HY-B1085
-
|
Compound 64716
|
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
|
|
Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis .
|
-
-
- HY-B0593A
-
|
GR20263 pentahydrate
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
|
-
-
- HY-14865
-
|
PTK 0796; Amadacycline
|
Bacterial
Antibiotic
|
Infection
|
|
Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
-
- HY-141619A
-
|
|
Bacterial
|
Infection
|
|
Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:19), an antibacterial agent, is a Trimethoprim (HY-B0510) and Sulfamethoxazole (HY-B0322) mixture. The ratio of Trimethoprim to Sulfamethoxazole in the combination mixture is 1 : 19 .
|
-
-
- HY-B0187A
-
|
S 4661 monohydrate
|
Bacterial
Antibiotic
|
Infection
|
|
Doripenem (S 4661) monohydrate, a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria .
|
-
-
- HY-B0187
-
|
S 4661
|
Bacterial
Antibiotic
|
Infection
|
|
Doripenem (S 4661), a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria .
|
-
-
- HY-B0510S
-
|
|
Antifolate
Bacterial
Antibiotic
|
Infection
|
|
Trimethoprim-d9 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment .
|
-
-
- HY-14865B
-
|
PTK 0796 tosylate; Amadacycline tosylate
|
Bacterial
Antibiotic
|
Infection
|
|
Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
-
- HY-141619
-
|
|
Bacterial
|
Infection
|
|
Cotrimoxazole (Trimethoprim/sulfamethoxazole 1:5), an antibacterial agent, is a Trimethoprim (HY-B0510) and Sulfamethoxazole (HY-B0322) mixture. The ratio of Trimethoprim to Sulfamethoxazole in the combination mixture is 1 : 5 .
|
-
-
- HY-N0195
-
|
2-Nitroimidazole
|
MOFs
Bacterial
Antibiotic
|
Infection
|
|
Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.
|
-
-
- HY-B1484
-
|
Latamoxef sodium; Lamoxactam sodium; LY-127935 sodium
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Moxalactam (Latamoxef) sodium salt is a synthetic oxa-β-lactam antibiotic. Moxalactam sodium salt has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam sodium salt inhibits production of β-lactamases .
|
-
-
- HY-B0510C
-
|
|
Antifolate
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Trimethoprim lactate is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim lactate is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim lactate has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim lactate can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
|
-
-
- HY-14865C
-
|
PTK0796 hydrochloride; Amadacycline hydrochloride
|
Bacterial
Antibiotic
|
Infection
|
|
Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
-
- HY-B1781
-
|
Sulfachlorpyridazine
|
Bacterial
Antibiotic
|
Infection
|
|
Sulfachloropyridazine is a broad spectrum sulfonamide that can be used against both gram-positive and gram-negative aerobic bacteria as well as Chlamydia. Sulfachloropyridazine is also considered as a common pollutant in surface and groundwater. Sulfachloropyridazine via electro-Fenton is a model for sulfonamide antibiotics that are widespread in waters .
|
-
-
- HY-18324
-
CRS3123
1 Publications Verification
REP-3123
|
Antibiotic
|
Inflammation/Immunology
|
|
CRS3123 is a potent and orally active narrow-spectrum antibiotic. CRS3123 inhibits bacterial methionyl-tRNA synthetase. CRS3123 has potent activity against Clostridium difficile (C. difficile) and aerobic Gram-positive bacteria but little activity against Gram-negative bacteria, including anaerobes. CRS3123 has the potential for the research of C. difficile infections .
|
-
-
- HY-B1923S
-
-
-
- HY-P3914
-
|
Oct-CA(1-7)M(2-9)
|
Bacterial
|
Infection
|
|
Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .
|
-
-
- HY-B1369R
-
|
N-Formimidoyl thienamycin monohydrate (Standard); MK0787 monohydrate (Standard)
|
Reference Standards
Antibiotic
Bacterial
|
Infection
|
|
Imipenem (monohydrate) (Standard) is the analytical standard of Imipenem (monohydrate). This product is intended for research and analytical applications. Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections .
|
-
-
- HY-Y1106
-
|
|
Environmental Pollutants
Biochemical Assay Reagents
Bacterial
|
Infection
|
|
Tripotassium phosphate is a Bactericid with bactericidal activity primarily against Gram-negative bacteria. Tripotassium phosphate reduces the population counts of Enterobacteriaceae and Campylobacter in poultry skin rinsates. Tripotassium phosphate fails to reduce the population count of Enterococcus in poultry skin rinsates .
|
-
-
- HY-B0479S
-
|
Thiophenicol-d3; Dextrosulphenidol-d3
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Thiamphenicol-d3 is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
-
- HY-B0593R
-
|
GR20263 (Standard)
|
Beta-lactamase
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Ceftazidime (Standard) is the analytical standard of Ceftazidime. This product is intended for research and analytical applications. Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
|
-
-
- HY-B0593AR
-
|
GR20263 pentahydrate (Standard)
|
Beta-lactamase
Reference Standards
Bacterial
Antibiotic
|
Infection
Cancer
|
|
Ceftazidime (pentahydrate) (Standard) is the analytical standard of Ceftazidime (pentahydrate). This product is intended for research and analytical applications. Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
|
-
-
- HY-B0510R
-
|
|
Reference Standards
Antifolate
Bacterial
Antibiotic
Influenza Virus
|
Infection
|
|
Trimethoprim (Standard) is the analytical standard of Trimethoprim. This product is intended for research and analytical applications. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
|
-
-
- HY-B1127
-
|
N-Benzoyl-β-alanine
|
Antibiotic
Bacterial
|
Infection
Endocrinology
|
|
Betamipron (N-benzoyl-β-alanine) is a carbapenem β-lactam antibiotic with antibacterial activity against most Gram-positive and Gram-negative aerobic and anaerobic bacteria. Betamipron can target and inhibit renal organic anion transporters, alleviate renal injury caused by Cisplatin (HY-17394), without interfering with the biological activity of cisplatin. Betamipron is often used in combination with panipenem, which can attenuate the renal effects induced by panipenem and slightly promote the proliferation of Clostridium difficile in the cecum. Betamipron can be used in studies related to renal injury and bacterial infection .
|
-
-
- HY-B0510S2
-
|
|
Antifolate
Bacterial
Antibiotic
|
Infection
|
|
Trimethoprim-d3is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment .
|
-
-
- HY-B0510B
-
|
|
Antifolate
Bacterial
Antibiotic
Influenza Virus
|
Infection
Cancer
|
|
Trimethoprim hydrochloride is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim hydrochloride is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim hydrochloride has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim hydrochloride can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
|
-
-
- HY-B0593S
-
|
GR20263-d5
|
Isotope-Labeled Compounds
Antibiotic
Beta-lactamase
Bacterial
|
Infection
Cancer
|
|
Ceftazidime-d5 (GR20263-d5) is the deuterium labeled Ceftazidime (HY-B0593). Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
|
-
-
- HY-B0479R
-
|
Thiophenicol (Standard); Dextrosulphenidol (Standard)
|
Beta-lactamase
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Thiamphenicol (Standard) is the analytical standard of Thiamphenicol. This product is intended for research and analytical applications. Thiamphenicol (Thiophenicol), a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
-
- HY-136382S
-
|
Sulfachlorpyridazine-d4
|
Antibiotic
Bacterial
|
Inflammation/Immunology
|
|
Sulfachloropyridazine-d4 is the deuterium labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria .
|
-
-
- HY-B1484A
-
|
Latamoxef; Lamoxactam; LY-127935
|
Beta-lactamase
Bacterial
Antibiotic
|
Infection
|
|
Moxalactam (Latamoxef) is a synthetic oxa-β-lactam antibiotic. Moxalactam has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Moxalactam inhibits production of β-lactamases .
|
-
-
- HY-B0187AR
-
|
S 4661 monohydrate (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Doripenem (monohydrate) (Standard) is the analytical standard of Doripenem (monohydrate). This product is intended for research and analytical applications. Doripenem (S 4661) monohydrate, a 1β-methyl parenteral carbapenem, has very broad-spectrum activity against Gram-positive and Gram-negative aerobic bacteria .
|
-
-
- HY-B1781R
-
|
Sulfachlorpyridazine (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Sulfachloropyridazine (Standard) is the analytical standard of Sulfachloropyridazine. This product is intended for research and analytical applications. Sulfachloropyridazine is a broad spectrum sulfonamide that can be used against both gram-positive and gram-negative aerobic bacteria as well as Chlamydia. Sulfachloropyridazine is also considered as a common pollutant in surface and groundwater. Sulfachloropyridazine via electro-Fenton is a model for sulfonamide antibiotics that are widespread in waters .
|
-
-
- HY-U00380
-
|
|
Antibiotic
Beta-lactamase
Bacterial
|
Infection
|
|
Tigemonam is an orally active monobactam antibiotic with a Ki of 0.86 μM against Enterobacter cloacae P99 β-lactamase and 50.8 μM against Escherichia coli TEM-1 β-lactamase. Tigemonam binds to penicillin-binding proteins 1a, 3, and 4, inhibits bacterial cell wall synthesis, and exhibits bactericidal activity against aerobic gram-negative bacteria including Enterobacteriaceae, Haemophilus influenzae, and Neisseria gonorrhoeae. Tigemonam resists hydrolysis by multiple β-lactamase enzymes, reduces bacterial load in systemic, pyelonephritic, lung, and thigh muscle infections in rodents, and shows minimal difference between minimum inhibitory and bactericidal concentrations. Tigemonam can be used for the research of gram-negative bacterial infections, acute pyelonephritis, lung infection, and thigh muscle infection .
|
-
-
- HY-129949
-
|
|
Antibiotic
Bacterial
|
Infection
Cancer
|
|
Aztreonam (lysine) is a monocyclic beta-lactam antibiotic, and has a very high affinity for penicillin-binding protein 3 (PBP-3). Aztreonam (lysine) is active against Gram-negative aerobic bacteria .
|
-
-
- HY-B0510A
-
|
|
Antifolate
Bacterial
Antibiotic
Influenza Virus
|
Infection
Cancer
|
|
Trimethoprim sulfate is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim sulfate is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim sulfate has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim sulfate can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
|
-
-
- HY-B0510S3
-
|
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
Antifolate
Influenza Virus
|
Others
|
|
Trimethoprim- 13C3 is the deuterium labeled Trimethoprim (HY-B0510) . Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
|
-
-
- HY-14865BR
-
|
PTK 0796 tosylate (Standard); Amadacycline tosylate (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Omadacycline (tosylate) (Standard) is the analytical standard of Omadacycline (tosylate). This product is intended for research and analytical applications. Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
-
- HY-B1085R
-
|
Compound 64716 (Standard)
|
Reference Standards
Bacterial
Antibiotic
DNA/RNA Synthesis
|
Infection
|
|
Cinoxacin (Standard) is the analytical standard of Cinoxacin. This product is intended for research and analytical applications. Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis .
|
-
-
- HY-B1085S
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
Cinoxacin-d5 is the deuterium-labeled Cinoxacin (HY-B1085) . Cinoxacin (Compound 64716),a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis .
|
-
-
- HY-121195
-
|
PC-904
|
Bacterial
|
Infection
|
|
Apalcillin (PC-904) in combination with Ro 48-1220, a penam sulfone β-lactamase inhibitor, demonstrated broad-spectrum activity against gram-negative aerobic and anaerobic bacteria, excluding Klebsiella oxytoca. It exhibited potent activity against β-lactamase-producing Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with effective MICs (11 μg/mL). The combination also inhibited Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter species at low MICs (0.25 to 4 μg/mL). However, its efficacy against oxacillin-resistant staphylococci and certain gram-positive organisms was limited. Apalcillin/Ro 48-1220 showed comparable efficacy to piperacillin/tazobactam against some extended-spectrum β-lactamase-producing Escherichia coli but was less effective against SHV-type β-lactamases .
|
-
-
- HY-B1894
-
|
Ro 15-8075 free base
|
Antibiotic
Bacterial
|
Infection
|
|
Cefetamet pivoxyl (Ro 15-8075 free base) is an orally active cephalosporin Antibiotic and a prodrug of Cefetamet (HY-A0111). After ingestion, Cefetamet pivoxyl is hydrolyzed by gastrointestinal esterases to form Cefetamet. Cefetamet pivoxyl is primarily active against aerobic Gram-negative bacteria (such as Enterobacteriaceae, *Neisseria*, *Haemophilus*) and some Gram-positive bacteria (such as non-enterococcal streptococci). Cefetamet pivoxyl exhibits potent in vivo antibacterial activity against strains of Gram-positive bacteria (S. pyogenes) and Gram-negative bacteria (E. coli, K. pneumoniae, S. marcescens, P. vulgaris, P. mirabilis, H. influenzae) .
|
-
-
- HY-B1781S
-
|
Sulfachlorpyridazine-13C6
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Sulfachloropyridazine- 13C6 is the 13C6 labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria.
|
-
-
- HY-N0195R
-
|
2-Nitroimidazole (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Azomycin (Standard) is the analytical standard of Azomycin. This product is intended for research and analytical applications. Azomycin (2-Nitroimidazole) is an antibiotic which can be active against aerobic Gram-positive and Gram-negative bacteria.
|
-
-
- HY-23848
-
|
non-8-ynoic acid
|
Bacterial
|
Infection
|
|
8-Nonynoic acid (non-8-ynoic acid) is a fatty acid that belongs to the group of octynoic acids. It exhibits antibacterial activity against gram-positive bacteria by binding to bacterial fatty acids. 8-Nonynoicacid also inhibits growth of gram-negative bacteria by inhibiting the synthesis of fatty acids. It is also capable of inhibiting growth of both aerobic and anaerobic bacteria in biochemical assays.
|
-
-
- HY-116974
-
|
ent-Thiophenicol; ent-Dextrosulphenidol
|
Antibiotic
|
Others
|
|
ent-Thiamphenicol (ent-Dextrosulphenidol) is a enantiomer of Thiamphenicol (HY-B0479). Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
|
-
- HY-14865A
-
|
PTK 0796 mesylate; Amadacycline mesylate
|
Bacterial
Antibiotic
|
Infection
|
|
Omadacycline (PTK 0796) mesylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline mesylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline mesylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline mesylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
- HY-14865R
-
|
PTK 0796 (Standard); Amadacycline (Standard)
|
Reference Standards
Bacterial
Antibiotic
|
Infection
|
|
Omadacycline (Standard) is the analytical standard of Omadacycline. This product is intended for research and analytical applications. Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
|
-
- HY-14865CR
-
|
PTK0796 hydrochloride (Standard); Amadacycline hydrochloride (Standard)
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Reference Standards
Bacterial
Antibiotic
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Infection
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Omadacycline (hydrochloride) (Standard) is the analytical standard of Omadacycline (hydrochloride). This product is intended for research and analytical applications. Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections[1][2][3][4].
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- HY-121120
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Antibiotic
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Infection
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Isosulfazecin (iSZ) is a novel β-lactam antibiotic produced by Pseudomonas acidophilus sp., synthesized in a nutrient solution supplemented with glycerol and sodium thiosulfate under aerobic conditions in parallel with bacterial growth. It is purified by chromatography and crystallization from aqueous methanol. Physicochemical analysis determined its molecular formula to be C12H20N4O9S, showing a structure with a β-lactam ring, methoxyl and sulfonate groups. Acid hydrolysis yields L-alanine and D-glutamic acid. iSZ is a diastereomer of sulfadiazine and exhibits moderate activity against both gram-positive and gram-negative bacteria, but potent activity against bacteria resistant to β-lactam antibiotics .
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- HY-B1127R
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N-Benzoyl-β-alanine (Standard)
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Reference Standards
Bacterial
Antibiotic
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Infection
Endocrinology
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Betamipron (Standard) is the analytical standard of Betamipron (HY-B1127). This product is intended for research and analytical applications. Betamipron (N-benzoyl-β-alanine) is a carbapenem β-lactam antibiotic with antibacterial activity against most Gram-positive and Gram-negative aerobic and anaerobic bacteria. Betamipron can target and inhibit renal organic anion transporters, alleviate renal injury caused by Cisplatin (HY-17394), without interfering with the biological activity of cisplatin. Betamipron is often used in combination with panipenem, which can attenuate the renal effects induced by panipenem and slightly promote the proliferation of Clostridium difficile in the cecum. Betamipron can be used in studies related to renal injury and bacterial infection .
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- HY-B0479S1
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Thiophenicol-d3-1; Dextrosulphenidol-d3-1
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Isotope-Labeled Compounds
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Infection
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Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol),a methyl-sulfonyl derivative of Chloramphenicol,is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit,leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative,Gram-positive aerobic and anaerobic bacteria) .
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- HY-185351
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Ampicillin/Sulbactam combination
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Bacterial
Antibiotic
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Infection
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Ampicillin sodium and Sulbactam sodium are formed by mixing HY-B0522A Ampicillin sodium with HY-B0334A Sulbactam sodium (each 1.5 g of this product contains 1 g amoxicillin sodium and 0.5 g sulbactam sodium). Ampicillin is a β-lactam antimicrobial, whereas sulbactam is a β-lactamase inhibitor. Ampicillin has a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. However, ampicillin is degraded by beta-lactamases. The combination of ampicillin and sulbactam demonstrates synergy in addressing bacterial strains resistant to ampicillin, thus providing broader coverage. Bacteria susceptible to ampicillin/sulbactam include Haemophilus influenzae, Escherichia coli, Acinetobacter, Klebsiella, Staphylococcus aureus, Enterobacter, and anaerobes.
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- HY-116558
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Bacterial
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Infection
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E-4441 is an orally active Antibacterial agent. E-4441 exerts broad-spectrum in vitro antibacterial activity against Gram-positive bacteria and aerobic bacteria. E-4441 exhibits protective effects against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa infections. E-4441 can be used in the research of systemic bacterial infections (Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa infections) .
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Product Name |
Type |
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- HY-Y1106
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Biochemical Assay Reagents
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Tripotassium phosphate is a Bactericid with bactericidal activity primarily against Gram-negative bacteria. Tripotassium phosphate reduces the population counts of Enterobacteriaceae and Campylobacter in poultry skin rinsates. Tripotassium phosphate fails to reduce the population count of Enterococcus in poultry skin rinsates .
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Product Name |
Target |
Research Area |
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- HY-P3914
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Oct-CA(1-7)M(2-9)
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Bacterial
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Infection
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Cecropin A (1-7)-Melittin A (2-9) is an antimicrobial peptide with antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative aerobic bacteria, as well as antimalarial activity, without the adverse hemolytic properties of bee venom peptides .
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Product Name |
Category |
Target |
Chemical Structure |
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Product Name |
Chemical Structure |
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- HY-B0510S
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Trimethoprim-d9 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment .
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- HY-B1923S
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Piperacillin-d5 is deuterium labeled Piperacillin. Piperacillin is kind of semisynthetic penicillins. Piperacillin has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria. Piperacillin has shown greater activity against β-lactamase-producing organisms than the other penicillins .
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- HY-B0479S
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Thiamphenicol-d3 is a deuterium labeled Thiamphenicol. Thiamphenicol, a methyl-sulfonyl derivative of Chloramphenicol, is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit, leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative, Gram-positive aerobic and anaerobic bacteria) .
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- HY-B0510S2
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Trimethoprim-d3is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment .
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- HY-B0593S
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Ceftazidime-d5 (GR20263-d5) is the deuterium labeled Ceftazidime (HY-B0593). Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases .
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- HY-136382S
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Sulfachloropyridazine-d4 is the deuterium labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria .
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- HY-B0510S3
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Trimethoprim- 13C3 is the deuterium labeled Trimethoprim (HY-B0510) . Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
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- HY-B1085S
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Cinoxacin-d5 is the deuterium-labeled Cinoxacin (HY-B1085) . Cinoxacin (Compound 64716),a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis .
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- HY-B1781S
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Sulfachloropyridazine- 13C6 is the 13C6 labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria.
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- HY-B0479S1
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Thiamphenicol-d3-1 (Thiophenicol-d3-1; Dextrosulphenidol-d3-1) is the deuterium-labeled Thiamphenicol (HY-B0479) . Thiamphenicol (Thiophenicol),a methyl-sulfonyl derivative of Chloramphenicol,is a broad-spectrum antimicrobial antibiotic. Thiamphenicol acts by binding to the 50S ribosomal subunit,leading to inhibition of protein synthesis and bacteriostatic effect (against Gram-negative,Gram-positive aerobic and anaerobic bacteria) .
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