5 Results for "

HDFs

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "HDFs" in MCE Product Catalog:

Cat. No.: HY-W747516
CAS No.: 352304-41-7
Butylcycloheptylprodigiosin is the secondary metabolite produced by some bacteria, such as Streptomyces. Butylcycloheptylprodigiosin is a red-pigmented antibiotic and exhibits cytotoxicity against cancer cell MCF-7 and HDF .
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Cat. No.: HY-N1190
CAS No.: 1177-14-6
Synonyms: (±)-Syringaresinol
DL-Syringaresinol ((±)-Syringaresinol), a lignin, inhibits UVA-induced upregulation of MMP-1 by suppressing MAPK/AP-1 signaling in human HaCaT keratinocytes and dermal fibroblasts (HDFs). DL-Syringaresinol has antiphotoaging properties against UVA-induced skin aging. DL-Syringaresinol exhibits weak antimycobacterial activity against Mycobacterium tuberculosis H37Rv .
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Cat. No.: HY-149367
CAS No.: 3049419-74-8
Target:  

Apoptosis

Research Areas:  

Cancer

Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM; HY-15230), has an IC50 of 3.38 μM for HDF and a Kd of 3.86 μM for Hsp90. Anticancer agent 136 is an apoptosis-inducing agent .
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Cat. No.: HY-144808
CAS No.: 2760658-33-9
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Anticancer agent 40 (compound 3e) is a potent anticancer agent. Anticancer agent 40 shows anticancer activities with IC50s of 0.94, 0.98, 0.96, 0.95, 2.13 nM for SKBR-3, SKOV-3, PC-3, U-87, HDF cells, respectively .
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Cat. No.: HY-155105
CAS No.: 2966859-35-6
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-Glucosidase-IN-30 (compound 8c) is a potent, orally active, competitive inhibitor against α-glucosidase, with Ki  of 40.0 µM and IC50 value of 49.0 µM. α-Glucosidase-IN-30 is non-cytotoxic against the cancer and normal cell lines MCF-7 and HDF, and can be used for Type 2 diabetes study .
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