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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
HIPK1
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "HIPK1" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-U00439A
CAS No.: 2321337-71-5
Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC50s of 136 and 74 nM for HIPK1 and HIPK2, and a Kd of 9.5 nM for HIPK2.
MU1210 (compound 12f), a chemical probe, is an inhibitor of CDC-like kinases Clk1, Clk2, and Clk4 (with IC50 values of 8, 20, and 12 nM respectively), with IC50 for HIPK1 and DYRK2 are 187 and 1309 nM. MU1210 also has favorable pharmacokinetic characteristics (in mice, 10 mg/kg, intraperitoneal injection: Cmax=1.24 μM, T1/2=58 minutes; no acute toxicity observed) [1].
Cat. No.: HY-177416
CAS No.: 2624098-97-9
MU1787 is a highly selective homeodomain-interacting protein kinase (HIPK) inhibitor with a furopyridine core, and shows improved selectivity against CLKs, with inactivity against DYRK1B, DYRK2, and MLK2/3 in in vitro cellular assays. MU1787 can be used for the research of malignancies [1].
Cat. No.: HY-RS17765
Target:
Research Areas:
Hipk1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hipk1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24232
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Research Areas:
Hipk1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hipk1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06181
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Research Areas:
HIPK1 Human Pre-designed siRNA Set A contains three designed siRNAs for HIPK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P701693
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HIPK1; Homeodomain-interacting protein kinase 1; Nuclear body-associated kinase 2
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Source:
Cat. No.: HY-P701694
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HIPK1; Homeodomain-interacting protein kinase 1; Nuclear body-associated kinase 2
Species:
Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
