34 Results for "

HIV-1 entry inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "HIV-1 entry inhibitor" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-N4100
CAS No.: 4192-90-9
Trilobatin, a natural sweetener derived from Lithocarpus polystachyus Rehd , Trilobatin is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope . Neuroprotective effects . Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells .
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Cat. No.: HY-P1066
CAS No.: 217082-57-0
Research Areas:  

Infection

Apelin-17(human, bovine) is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-17(human, bovine) binds to human APJ receptors expressed in HEK 293 cells (pIC50=9.02). Apelin-17(human, bovine) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
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Cat. No.: HY-115488A
CAS No.: 1859189-55-1
Target:  

HIV

Research Areas:  

Infection

BNM-III-170, CD4-mimeticcompound, is an anti-HIV-1 agent. BNM-III-170 binds to the Phe43 cavity of HIV 1 gp120. BNM-III-170 can inhibits HIV-1 viral entry into target cells. BNM-III-170 can be used for the research of HIV-1 infection .
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Cat. No.: HY-P1064
CAS No.: 252642-12-9
Apelin-36(human) is an endogenous orphan G protein-coupled receptor APJ agonist, with an EC50 of 20 nM. Apelin-36(human) shows high affinity to human APJ receptors expressed in HEK 293 cells (pIC50=8.61). Apelin-36 has been linked to two major types of biological activities: cardiovascular and metabolic. Apelin-36(human) inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
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Cat. No.: HY-P991246

Target:  

Virus Protease HIV

Research Areas:  

Infection

VRC01LS is a humanized monoclonal antibody inhibitor targeting the CD4-binding site of HIV-1 envelope glycoprotein (Env). VRC01LS blocks the binding of HIV-1 to host cell CD4 receptor, inhibiting viral entry. VRC01LS is promising for research of HIV-1 infection .
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Cat. No.: HY-107401
CAS No.: 370893-06-4
Synonyms: SCH-351125
Target:  

HIV CCR Calcium Channel

Research Areas:  

Infection

Ancriviroc (SCH-351125) is an orally active CCR5 antagonist with an IC50 value of 13 nM against hCCR5. Ancriviroc specifically binds to hCCR5, blocks ligand-induced signal transduction, calcium influx, GTPγS binding, chemotaxis, ligand binding, and HIV-1 entry, induces conformational changes in CCR5, and inhibits infection and replication of R5-tropic HIV-1 .
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Cat. No.: HY-76648
CAS No.: 333353-44-9
Target:  

HIV

Research Areas:  

Infection

NBD-556, a CD4 mimetic, is a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. NBD-556 shows potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels .
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Cat. No.: HY-P1065
CAS No.: 230299-95-3
Apelin-36(rat, mouse) is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-36(rat, mouse) binds to APJ receptors with an IC50 of 5.4 nM, and potently inhibits cAMP production with an EC50 of 0.52 nM. Apelin-36(rat, mouse) blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ .
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Cat. No.: HY-125183
CAS No.: 2974489-09-1
Target:  

HIV

Research Areas:  

Infection

BMS-818251 is a HIV-1 attachment and entry inhibitor. BMS-818251 binds to HIV-1 Env gp120, interferes with viral attachment and entry processes, and inhibits HIV-1 viral replication. BMS-818251 can be used in studies related to HIV-1 infection .
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Cat. No.: HY-P1064A
Apelin-36(human) TFA is an endogenous orphan G protein-coupled receptor APJ agonist, with an EC50 of 20 nM. Apelin-36(human) TFA shows high affinity to human APJ receptors expressed in HEK 293 cells (pIC550=8.61). Apelin-36(human) TFA has been linked to two major types of biological activities: cardiovascular and metabolic. Apelin-36(human) TFA inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
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Cat. No.: HY-N3222
CAS No.: 55497-79-5
Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41. Myriceric acid B is an antitumor agent .
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Cat. No.: HY-163362
Research Areas:  

Infection

HIV-1 inhibitor-65 (compound 3c) is an inhibitor of HIV-1 (EC50: 2.9 nM) and an activator of protein kinase C (PKC). HIV-1 inhibitor-65 inhibits syncytium formation (EC50: 7.0 nM) and inhibits HIV-1 entry and HIV-1 reverse transcriptase .
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Cat. No.: HY-N4100R
CAS No.: 4192-90-9
Trilobatin (Standard) is the analytical standard of Trilobatin. This product is intended for research and analytical applications. Trilobatin, a natural sweetener derived from?Lithocarpus polystachyus?Rehd , Trilobatin?is an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope . Neuroprotective effects . Trilobatin is also a SGLT1/2 inhibitor that selectively induces the proliferation of human hepatoblastoma cells .
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Cat. No.: HY-123902
CAS No.: 19022-51-6
Synonyms: Zizanin A
Target:  

CCR HIV

Research Areas:  

Infection

Ophiobolin C inhibits CCR5 binding to the envelop protein gp120 and CD4, which is responsible for mediating the entry of HIV-1 into cells . Ophiobolin C is also cytotoxic to chronic lymphocytic leukemia cells .
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Cat. No.: HY-P4810
CAS No.: 229030-20-0
Synonyms: T140
Target:  

CXCR

Research Areas:  

Infection

Polyphemusin II-Derived Peptide (T140), a CXCR4 inhibitor, shows high inhibitory activity against HIV-1 entry and the inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody (12G5) to CXCR4 .
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Cat. No.: HY-P1066A
Research Areas:  

Infection

Apelin-17(human, bovine) TFA is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-17(human, bovine) TFA binds to human APJ receptors expressed in HEK 293 cells (pIC50=9.02). Apelin-17(human, bovine) TFA inhibits the entry of some HIV-1 and HIV-2 into the NP2/CD4 cells expressing APJ .
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Cat. No.: HY-123884
CAS No.: 716354-87-9
Target:  

CCR HIV

Research Areas:  

Infection

GSK-214096 is a selective CCR5 antagonist and an inhibitor of HIV-1 entry. GSK-214096 inhibits HIV-1 glycoprotein 120 (gp120) .
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Cat. No.: HY-172603
CAS No.: 43099-56-5
Target:  

HIV

Research Areas:  

Infection

HIV-1-IN-82 (Compound L14) is an orally active small-molecule entry inhibitor for HIV-1 with an IC50 value of 0.39 μM. HIV-1 inhibitor-82 is promising for research of anti-HIV-1 infection .
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Cat. No.: HY-P10437
CAS No.: 339332-64-8
Synonyms: human α1-AT(353-372)
Target:  

HIV

Research Areas:  

Infection

VIRIP (human α1-AT(353-372)) is a HIV-1 inhibitor. VIRIP blocks the entry of HIV-1 by interacting with gp41 fusion peptide. VIRIP can be used for virus research .
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Cat. No.: HY-116113
CAS No.: 1286237-83-9
Target:  

HIV DNA/RNA Synthesis

Research Areas:  

Infection

SJP-L-5 is an HIV-1 capsid dissociation inhibitor. SJP-L-5 exhibits inhibitory activity against multiple HIV-1 strains, with an EC50 ranging from 0.16 to 0.97 μg/mL. SJP-L-5 inhibits viral infection by blocking HIV-1 viral DNA entry into the nucleus. SJP-L-5 can be used in HIV-1 infection research .
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