5 Results for "

HPI

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "HPI" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-100790
CAS No.: 302803-72-1
Purity:  98.57%
Synonyms: HPI-4
Target:  

Hedgehog

Research Areas:  

Cancer

Ciliobrevin A (HPI-4) is a hedgehog (Hh) signaling pathway inhibitor with median inhibitory concentration (IC50) less than 10 μM .
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2
2 Cited Publications
Cat. No.: HY-12895
CAS No.: 24418-86-8
Purity:  98.95%
Target:  

SphK PI3K Apoptosis

Research Areas:  

Cancer

SKI V is a noncompetitive and potent non-lipid sphingosine kinase (SPHK; SK) inhibitor with an IC50 of 2 μM for GST-hSK. SKI V potently inhibits PI3K with an IC50 of 6 μM for hPI3k. SKI V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P). SKI V induces apoptosis and has antitumor activity .
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1
1 Cited Publications
Cat. No.: HY-120536
CAS No.: 13080-21-2
Purity:  ≥98.0%
Target:  

Bacterial

Research Areas:  

Infection

HPi1 is a potent, selective and orally active antimicrobial against Helicobacter pylori with an IC50 of 0.24 μM and an MIC of 0.08-0.16 μg/mL. HPi1 is inactive against other bacteria, including the gut commensals Lactobacillus casei, Lactobacillus reuteri, and Bifidobacterium longum .
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Cat. No.: HY-156814
CAS No.: 3093738-79-2
Target:  

Hedgehog

Research Areas:  

Cancer

HPP-9 is a Proteolysis-Targeting Chimeras (PROTACs) based on Hedgehog Pathway Inhibitor-1 (HPI-1), with the pIC50 of 6.71, that can degrade BET bromodomains. HPP-9 has antitumor activity [1[.
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Cat. No.: HY-160240
CAS No.: 210541-64-3
Target:  

Fluorescent Dye

Research Areas:  

Others Cancer

HPI is a HS - fluorescent probe (Ex/Em=280/410 nm). HPI can be used to detect the HS - form of hydrogen sulfide (H2S) gas in environmental water samples .
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