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HPTS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (1) Environmental Pollutants (1) Fluorescent Dye (4) Fungal (1) mTOR (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Cancer (2) Infection (1)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0023

Pyranine 2 Publications Verification HPTS; Solvent Green 7	Environmental Pollutants Fluorescent Dye	Others
Pyranine (HPTS; Solvent Green 7) is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu ⁺ ion. Pyranine is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .

HY-W011689

6PPD 1 Publications Verification	Reactive Oxygen Species (ROS)	Others
6PPD is a rubber antioxidant that scavenges ozone and forms nitro radicals. Exposure to 6PPD reduces the hatching rate, impairs spontaneous locomotor activity, shortens body length and causes malformations in zebrafish embryos. 6PPD also induces oxidative stress in zebrafish embryos .

HY-103467

*NPE-caged-HPTS* sodium**	Fluorescent Dye	Others
NPE-caged-HPTS sodium is a caged fluorophore that fluoresces upon uncaged fluorophore release, releasing the free highly polar fluorophore HPTS (Exc=470/40 nm, Em=525/50 nm). HPTS releases the fluorophore rapidly and uniformly, allowing for measurement of diffusion within tissues, with a diffusion coefficient of μm ²s ^-1, similar to that of synaptic L-glutamate .

HY-D0023A

Pyranine hydrate HPTS hydrate; Solvent Green 7 hydrate	Fluorescent Dye	Others
Pyranine (HPTS; Solvent Green 7) hydrate is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine hydrate acts as a class of fluorescent chemosensor for the Cu ⁺ ion. Pyranine hydrate is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .

HY-D0116

Pyranine free acid HPTS free acid; Solvent Green 7 free acid	Fluorescent Dye	Others
Pyranine (HPTS; Solvent Green 7) free acid is a pH-sensitive fluorescent indicator. Pyranine free acid acts as a class of fluorescent chemosensor for the Cu ⁺ ion. Pyranine free acid is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .

HY-173141

mTOR inhibitor-26	mTOR	Cancer
mTOR inhibitor-26 (Compound HPT-11) is an inhibitor of mTOR with an IC₅₀ of 0.7 nM. It effectively inhibits the proliferation of AML cell lines Molm-13 and MV-4-11. mTOR inhibitor-26 exhibits antitumor activity and favorable metabolic stability, making it a promising candidate for cancer research .

HY-N14135

Cystothiazole A	Fungal	Infection Cancer
Cystothiazole A has antifungal activity. Cystothiazole A can inhibit candida albicans, saccharomyces cerevisiae and aspergillus smoke with MIC values of 0.4 μg/mL, 0.1 μg/mL and 1.6 μg/mL, respectively. Cystothiazole A also inhibits human tumor cell, such as HPT-116 and K562 cells with MIC values of 130 ng/mL and 110 ng/mL, respectively. Cystothiazole A has no anti-bacterial effect .

HY-W187463

2-Mercaptopyridin-3-ol 3-HPT	Drug Derivative	Others
2-Mercaptopyridin-3-ol (3-HPT) is a natural product with strong metal coordination ability. 2-Mercaptopyridin-3-ol can be used as a metal enzyme inhibitor .

Cat. No.	Product Name	Type

HY-D0023

Pyranine 2 Publications Verification HPTS; Solvent Green 7	Fluorescent Dye
Pyranine (HPTS; Solvent Green 7) is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine acts as a class of fluorescent chemosensor for the Cu ⁺ ion. Pyranine is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .

HY-D0023A

Pyranine hydrate HPTS hydrate; Solvent Green 7 hydrate	Fluorescent Dye
Pyranine (HPTS; Solvent Green 7) hydrate is a cell-impermeant pH-sensitive fluorescent indicator. Pyranine hydrate acts as a class of fluorescent chemosensor for the Cu ⁺ ion. Pyranine hydrate is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .

HY-D0116

Pyranine free acid HPTS free acid; Solvent Green 7 free acid	Fluorescent Dye
Pyranine (HPTS; Solvent Green 7) free acid is a pH-sensitive fluorescent indicator. Pyranine free acid acts as a class of fluorescent chemosensor for the Cu ⁺ ion. Pyranine free acid is used as a coloring agent, biological stain, optical detecting reagent, and pH indicator (Ex/Em = 450/510 nm) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N14135

Cystothiazole A	Microorganisms Antibiotics Other Antibiotics Source Classification	Fungal
Cystothiazole A has antifungal activity. Cystothiazole A can inhibit candida albicans, saccharomyces cerevisiae and aspergillus smoke with MIC values of 0.4 μg/mL, 0.1 μg/mL and 1.6 μg/mL, respectively. Cystothiazole A also inhibits human tumor cell, such as HPT-116 and K562 cells with MIC values of 130 ng/mL and 110 ng/mL, respectively. Cystothiazole A has no anti-bacterial effect .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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HPTS

Inhibitors & Agonists

Fluorescent Dye

NaturalProducts

Natural
Products