4 Results for "

HR1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "HR1" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-116770
CAS No.: 1558598-41-6
Purity:  99.91%
Target:  

Endonuclease

Research Areas:  

Cancer

PFM01, N-alkylated Mirin derivative, is a MRE11 endonuclease inhibitor. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR) .
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Cat. No.: HY-P5727
CAS No.: 80533-94-4
Target:  

Bacterial

Research Areas:  

Infection

HR1 is a mastoid protease. HR1 can increase the permeability of human erythrocyte membrane. HR1 can induce cytoplasmic membrane permeation in bacteria and mast cells [1].
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Cat. No.: HY-P10804
Target:  

SARS-CoV

Research Areas:  

Infection

PIH is an antiviral peptide that effectively inhibits the HR1/HR2-mediated membrane fusion between MERS-CoV and host cells, with an IC50 of 1.171 μM. By forming a complex with gold nanorods (AuNRs), the antiviral efficacy of PIH can be further enhanced by 10-fold [1].
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Cat. No.: HY-P3492
Target:  

SARS-CoV

Research Areas:  

Infection

SARS-CoV-2-IN-34 (S-20-1) is a blood brain barrier penetrable pan-coronavirus (CoV) fusion inhibitor with broad-spectrum inhibitory activity. SARS-CoV-2-IN-34 effectively inhibits infection by pseudotyped and authentic SARS-CoV-2, and pseudotyped variants of concern (VOCs). SARS-CoV-2-IN-34 shows high affinity to RBD in S1 and HR1 domain in S2 of SARS-CoV-2 S protein. SARS-CoV-2-IN-34 can be used for the research of infection [1].
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