PIH
PIH is an antiviral peptide that effectively inhibits the HR1/HR2-mediated membrane fusion between MERS-CoV and host cells, with an IC50 of 1.171 μM. By forming a complex with gold nanorods (AuNRs), the antiviral efficacy of PIH can be further enhanced by 10-fold.
For research use only. We do not sell to patients.
- Formula: C207H340N48O72S2
- Molecular Weight:4717.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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Molecular Weight 4717.32
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Formula C207H340N48O72S2
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Sequence
Cys-Gly-Gly-Gly-Gly-Gly-Ser-Leu-Thr-Glu-Ile-Asn-Thr-Glu-Leu-Leu-Asp-Leu-Glu-Tyr-Glu-Met-Lys-Lys-Leu-Glu-Glu-Val-Val-Lys-Lys-Leu-Glu-Glu-Ser-Tyr-Ile-Asp-Leu-Lys-Glu-Leu
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Sequence Shortening
CGGGGGSLTEINTELLDLEYEMKKLEEVVKKLEESYIDLKEL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)