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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
IdeS
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "IdeS" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-E70365
CAS No.: 2764750-38-9
Target:
Research Areas:
IdeS protease is an IgG-specific endopeptidase, which is highly specific for the lower hinge region of IgG. IdeS protease represses innate immune responses to promote streptococcal survival in an inflammatory environment .
Cat. No.: HY-E70364
CAS No.: 1892548-76-3
Target:
Research Areas:
IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage .
Cat. No.: HY-E70365A
Target:
Research Areas:
IdeS (Immobilized, Microspin) is a resin that covalently couples IdeS protease to agarose beads and cleaves IgG at specific sites to generate F(ab')2 and Fc fragments. After IdeS (Immobilized, Microspin) digestion, F(ab')2 and Fc fragments are obtained in the solution without IdeS enzyme.
Cat. No.: HY-P703489
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IdeS; Streptococcus pyogenes
Cat. No.: HY-P74867A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Immunoglubulin-degrading enzyme; IdeS
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Protocols
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