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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Isofagomine
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Isofagomine" in MCE Product Catalog:
Synonyms: D-Isofagomine; Isofagomine
Target:
Research Areas:
Afegostat is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .
Synonyms: D-Isofagomine D-Tartrate; Isofagomine D-Tartrate
Target:
Research Areas:
Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .
Cat. No.: HY-14829F
CAS No.: 202979-51-9
Synonyms: 5-epi-Isofagomine
Target:
Research Areas:
L-Afegostat (5-epi-Isofagomine) is a glycosidase inhibitor. L-Afegostat is an iminosugar that can be used for the synthesis of carbohydrates. L-Afegostat shows enzyme inhibition to β-Glucosidase with an Ki of 30 μM .
Cat. No.: HY-14829A
CAS No.: 161302-93-8
Synonyms: D-Isofagomine hydrochloride; Isofagomine hydrochloride
Target:
Research Areas:
Afegostat hydrochloride (D-Isofagomine hydrochloride) is a potent β-galactosidase inhibitor with activity ameliorating GM1-gangliosidosis and Morquio B disease-associated mutations. Afegostat hydrochloride is able to induce the maturation of mutant β-galactosidase in fibroblasts from patients with GM1-gangliosidosis. Afegostat hydrochloride also promotes the reduction of keratin sulfate and oligosaccharide load in patient cells .
Cat. No.: HY-14829B
CAS No.: 919364-56-0
Synonyms: AT 2101; D-Isofagomine tartrate; Isofagomine tartrate
Target:
Research Areas:
Afegostat tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity .
Cat. No.: HY-N20714
CAS No.: 197449-09-5
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
