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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
KAT3B
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "KAT3B" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-W015239
CAS No.: 605-62-9
Target:
Research Areas:
KAT8-IN-1 is a lysine (K) acetyltransferase 8 (KAT8) inhibitor, with IC50s of 141 μM (KAT8), 221 μM (KAT2B), 106 μM (KAT3B), respectively. KAT8 inhibits histone acetyltransferases (HATs), and could result in disease states, such as cancer or inflammatory diseases .
3
3 Cited Publications
Cat. No.: HY-W013274
CAS No.: 357649-93-5
Target:
Research Areas:
CPTH2 is a potent histone acetyltransferase (HAT) inhibitor. CPTH2 selectively inhibits the acetylation of histone H3 by Gcn5. CPTH2 induces apoptosis and decreases the invasiveness of a clear cell renal carcinoma (ccRCC) cell line through the inhibition of acetyltransferase p300 (KAT3B) .
Target:
Research Areas:
L002 is a potent, cell permeable, reversible and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM . L002 binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain, blocks histone acetylation and p53 acetylation, and inhibits STAT3 activation . L002 has the potential for hypertension-induced cardiac hypertrophy and fibrogenesis treatment [3].
Cat. No.: HY-174868
CAS No.: 3055107-60-0
Research Areas:
iP300w (Compound 9) is a Histone acetyltransferase p300 (KAT3B) inhibitor. iP300w can be used for synthesis of PROTAC BT-O2C (HY-174866) .
Cat. No.: HY-RS04405
Target:
Research Areas:
EP300 Human Pre-designed siRNA Set A contains three designed siRNAs for EP300 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W013274A
CAS No.: 2108899-91-6
Target:
Research Areas:
CPTH2 hydrochloride is a potent histone acetyltransferase (HAT) inhibitor. CPTH2 hydrochloride selectively inhibits the acetylation of histone H3 by Gcn5. CPTH2 hydrochloride induces apoptosis and decreases the invasiveness of a clear cell renal carcinoma (ccRCC) cell line through the inhibition of acetyltransferase p300 (KAT3B) .
Cat. No.: HY-RS04406
Target:
Research Areas:
Ep300 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ep300 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-100671R
CAS No.: 321695-57-2
Research Areas:
L002 (Standard) is the analytical standard of L002 (HY-100671). This product is intended for research and analytical applications. L002 is a potent, cell permeable, reversible and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM . L002 binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain, blocks histone acetylation and p53 acetylation, and inhibits STAT3 activation . L002 has the potential for hypertension-induced cardiac hypertrophy and fibrogenesis treatment [3].
Cat. No.: HY-P702892
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: EP300; Histone Crotonyltransferase P300; EP300 Lysine Acetyltransferase; Histone Butyryltransferase P300; P300; Protein Lactyltransferas P300; Histone Acetyltransferase P300; E1A-Associated Protein P300; E1A Binding Protein P300; P300 HAT; KAT3B; E1A-Bind
Species:
Human
Source:
E. coli
Cat. No.: HY-P702963
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EP300; Histone Crotonyltransferase P300; EP300 Lysine Acetyltransferase; Histone Butyryltransferase P300; P300; Protein Lactyltransferas P300; Histone Acetyltransferase P300; E1A-Associated Protein P300; E1A Binding Protein P300; P300 HAT; KAT3B; E1A-Bind
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P7S0575
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EP300; Histone Crotonyltransferase P300; EP300 Lysine Acetyltransferase; Histone Butyryltransferase P300; P300; Protein Lactyltransferas P300; Histone Acetyltransferase P300; E1A-Associated Protein P300; E1A Binding Protein P300; P300 HAT; KAT3B; E1A-Binding Protein, 300kD; Protein 2-Hydroxyisobutyryltransferase P300; Histone Acetyltransferase; Protein Isonicotinyltransferase P300; MKHK2; Protein Propionyltransferase P300; RSTS2
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
