11 Results for "

LPS-induced BV-2 microglial cells

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "LPS-induced BV-2 microglial cells" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-170621
CAS No.: 2958649-56-2
STAT1/3-IN-1 is a potent STAT1/3 inhibitor with potent anti-inflammatory effect. STAT1/3-IN-1 inhibits phosphorylation and nuclear translocation of STAT1/3 to modulate microglial inflammation, reduces LPS (HY-D1056)-induced pro-inflammatory cytokines (NO, IL-1β, IL-6, and TNF-α) and inflammatory mediators (iNOS, COX-2). STAT1/3-IN-1 exhibits low toxicity in mice. STAT1/3-IN-1 can be used for the research of neuroinflammation .
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Cat. No.: HY-N8371
CAS No.: 142279-40-1
Shizukaol B is a lindenane-type dimeric sesquiterpene, used to be isolated from the whole plant of Chloranthus henryi. Shizukaol B has anti-inflammatory effect against lipopolysaccharide (LPS)-induced activation of BV2 microglial cells. Shizukaol B inhibits iNOS and COX-2, and suppresses NO production, TNF-α, and IL-1β expression .
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Cat. No.: HY-N15566
Theleganbanin D is a p-terphenyl derivative found in the Thelephora ganbajun. Theleganbanin D inhibits TNF-α, IL-6, and IL-1β production in LPS-induced BV-2 microglial cells. Theleganbanin D is promising for research of neurodegenerative diseases .
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Cat. No.: HY-155572
Target:  

Keap1-Nrf2

Research Areas:  

Inflammation/Immunology

Nrf2 activator-8 (compound 10e) is a Nrf2 activator (EC50=37.9 nM). Nrf2 activator-8 exhibits remarkable antioxidant and anti-inflammatory effects in BV-2 microglial cells. Nrf2 activator-8 can significantly restore spatial memory deficits in a mouse model of lipopolysaccharide (LPS)-induced neuroinflammation .
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Cat. No.: HY-N15570
CAS No.: 121254-55-5
2-O-Methylatromentin is an anti-neuroinflammatory agent. 2-O-Methylatromentin shows inhibitory activity on the production of pro-inflammatory cytokines TNF-α, IL-6 and IL-1β in Lipopolysaccharides (HY-D1056) (LPS) -induced BV-2 microglial cells. 2-O-Methylatromentin can be used for the study of neuroinflammatory related diseases .
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Cat. No.: HY-N13831
CAS No.: 2721-56-4
Swietenidine B is a quinoline alkaloid that can be isolated from the root bark of Dictamnus dasycarpus. Swietenidine B does not show significant activity in inhibiting NO production in LPS-induced BV-2 microglial cells .
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Cat. No.: HY-N21923
CAS No.: 126239-88-1
Euphoscopin H is a diterpenoid compound found in the fresh leaves and roots of Euphorbia helioscopia. Euphoscopin H shows weak inhibitory activity against LPS-induced NO production and no obvious cytotoxicity in the mouse microglial BV-2 cell model .
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Cat. No.: HY-N15564
CAS No.: 31554-34-4
Theleganbanin B is a p-terphenyl derivative found in the Thelephora ganbajun. Theleganbanin B inhibits TNF-α, IL-6, and IL-1β production in LPS-induced BV-2 microglial cells. Theleganbanin B inhibits the phosphorylation of JAK2/STAT3. Theleganbanin B is promising for research of neurodegenerative diseases .
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Cat. No.: HY-N19854
CAS No.: 2097442-40-3
Mariaterpenoside A is an inducible nitric oxide synthase (iNOS) inhibitor. Mariaterpenoside A interacts with the active cavity of iNOS protein via hydrogen bonds with specific residues of the binding site. Mariaterpenoside A suppresses NO release in LPS (HY-D1056)-induced murine microglial BV-2 cells. Mariaterpenoside A can be used for the research of neurodegenerative disease .
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Cat. No.: HY-N21762
CAS No.: 1280717-80-7
Petatewalide A is a bakkenolide-type sesquiterpene. Petatewalide A is isolated from Petasites tatewakianus. Petatewalide A inhibits NO production. Petatewalide A exhibits anticancer activity against cervical cancer, breast cancer, and Lewis lung cancer .
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