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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
LTK
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "LTK" in MCE Product Catalog:
Cat. No.: HY-160461
CAS No.: 71118-00-8
Target:
Research Areas:
LTK-14A, a derivative of Garcinol (HY-107569), is an orally effective selective inhibitor of histone butyrylation. LTK-14A selectively inhibits butyrylation without affecting acetylation by interacting with the C1438 residue in the catalytic domain of p300. LTK-14A significantly inhibits H4K5 butyrylation in vitro and downregulates the expression of adipogenic genes, thereby blocking adipogenesis. LTK-14A inhibits body weight gain and reduces body weight in obese mice. LTK-14A can be used in obesity-related research.
Target:
Research Areas:
KV1.3-IN-1 (Compound trans-18) is a KV1.3 channel inhibitor (IC50: 230 nM and 26.12 nM in Ltk cells and PHA-activated T-lymphocytes respectively). KV1.3-IN-1 impairs intracellular Ca 2+ signaling. KV1.3-IN-1 inhibits T-cell activation, proliferation, and colony formation .
Cat. No.: HY-RS07884
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Research Areas:
LTK Human Pre-designed siRNA Set A contains three designed siRNAs for LTK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19111
Target:
Research Areas:
Ltk Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ltk gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25601
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Research Areas:
Ltk Rat Pre-designed siRNA Set A contains three designed siRNAs for Ltk gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-171155
CAS No.: 1360282-15-0
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Research Areas:
CLIP1-LTK fusion protein regulator-1 is a 7-azaindol-6-amine class CLIP1-LTK fusion protein regulator and CLIP1-LTK fusion protein receptor inhibitor. CLIP1-LTK fusion protein regulator-1 suppresses abnormal proliferation of CLIP1-LTK-dependent cells.CLIP1-LTK fusion protein regulator-1 can be used for the research of non-small cell lung cancer .
Cat. No.: HY-131909
CAS No.: 2226742-61-4
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Research Areas:
CJ-2360 is a potent and orally active ALK inhibitor with IC50s of 2.2, 4.0, 8.8, 6.3, and 8.9 nM against wild-type ALK and F1197M, G1269A, L1196M, and S1206Y ALK mutants, respectively. CJ-2360 displays potent inhibitory activity against two clinically reported ALK mutants (C1156Y and L1196M) and a few other kinases (LTK, MERTK, CLK1, DAPK1, and DAPK2) among the 468 kinases evaluated .
Cat. No.: HY-P703767
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LTK; Protein Tyrosine Kinase 1; Leukocyte Receptor Tyrosine Kinase; Receptor Protein-Tyrosine Kinase; TYK1; Tyrosine-Protein Kinase Receptor; Leukocyte Tyrosine Kinase Receptor; Leukocyte Tyrosine Kinase
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P701795
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LTK; Protein Tyrosine Kinase 1; Leukocyte Receptor Tyrosine Kinase; Receptor Protein-Tyrosine Kinase; TYK1; Tyrosine-Protein Kinase Receptor; Leukocyte Tyrosine Kinase Receptor; Leukocyte Tyrosine Kinase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-12962A
CAS No.: 1784252-90-9
Target:
Research Areas:
NMDA-IN-1 dihydrochloride is a selective NMDA NR2B antagonist with a Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM. NMDA-IN-1 dihydrochloride inhibits Glu/Gly stimulated Ca2+ flux in Ltk- cells expressing the hNR1a/NR2B with a IC50 of 9.7 nM. NMDA-IN-1 dihydrochloride has no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor. NMDA-IN-1 dihydrochloride shows excellent activity in the mechanical hyperalgesia assay in rats. NMDA-IN-1 dihydrochloride can be used for the studies of stroke, parkinson, and neuropathic pain .
Cat. No.: HY-P71584
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ALKAL1; AUG-Beta; Prev. FAM150A; Augmentor-Alpha; UNQ9433; Protein FAM150A; AUGB; Augmentor-Beta; Family With Sequence Similarity 150 Member A; RPLK9433; Augmentor Beta; AUGA; ALK And LTK Ligand 1; Family With Sequence Similarity 150, Member A
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
