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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
M-8
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "M-8" in MCE Product Catalog:
1
Target:
Research Areas:
Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a "super-cooling agent" . Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response .
1
1 Cited Publications
Target:
Research Areas:
M8-B is a potent transient receptor potential melastatin-8 (TRPM8) antagonist. M8-B blocks cold-induced and TRPM8-agonist-induced activation TRPM8 channels. M8-B decreases deep body temperature (Tb) .
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Guanosine, 8-methyl-2′-O-methyl-
Synonyms: m8Gm
Cat. No.: HY-171544
Synonyms: AGS-16M8F
Cat. No.: HY-151002S
CAS No.: 2673270-31-8
Cat. No.: HY-169972
CAS No.: 3106182-23-1
Target:
Research Areas:
Succinate dehydrogenase-IN-5 (Compound M8) is the inhibitor for succinate dehydrogenase. Succinate dehydrogenase-IN-5 interfers with the energy metabolism and growth of fungi, inhibits Rhizoctonia solani, Sclerotinia sclerotiorum, Botrytis cinerea and Fusarium graminearum with EC50 < 0.3 μg/mL .
Cat. No.: HY-158534
Synonyms: Mannose-8 N-linked oligosaccharide; Oligomannose 8 glycan
Cat. No.: HY-158536
Synonyms: Mannose-8 N-linked oligosaccharide, 2-AA labelled; Oligomannose 8 glycan, 2-AA labelled
Cat. No.: HY-154242
CAS No.: 36799-17-4
Target:
Research Areas:
8-Methylguanosine (m(8)rG) is a purine nucleoside analog. The incorporation of 8-methylguanosine in oligonucleotides stabilizes the Z form more dramatically than does the incorporation of 8-methyl-2'-deoxyguanosine (m(8)G).
Cat. No.: HY-158539
Synonyms: Mannose-8 N-linked oligosaccharide, procainamide labelled; Oligomannose 8 glycan, procainamide labelled
Cat. No.: HY-110181R
CAS No.: 883976-12-3
Target:
Research Areas:
M8-B (Standard) is the analytical standard of M8-B (HY-110181). This product is intended for research and analytical applications. M8-B is a potent transient receptor potential melastatin-8 (TRPM8) antagonist. M8-B blocks cold-induced and TRPM8-agonist-induced activation TRPM8 channels. M8-B decreases deep body temperature (Tb) .
Cat. No.: HY-158538
Synonyms: Mannose-8 N-linked oligosaccharide, 2-AB labelled; Oligomannose 8 glycan, 2-AB labelled
Cat. No.: HY-175891
CAS No.: 2836274-72-5
Research Areas:
POI ligand-5 (Compound M8) is a SOS1 ligand that can be used to synthesize PROTACs, such as PROTAC SOS1 degrader-5 (HY-161173) .
Cat. No.: HY-11062R
CAS No.: 36945-98-9
Synonyms: AG-3-5 (Standard)
Target:
Research Areas:
Icilin (Standard) is the analytical standard of Icilin (HY-11062). This product is intended for research and analytical applications. Icilin (AG-3-5) is a super-agonist of the transient receptor potential M8 (TRPM8) ion channel. Icilin activates TRPM8 in EGTA in a dose-dependent manner (EC50=1.4 μM). Icilin is a "super-cooling agent" . Icilin attenuates autoimmune neuroinflammation through modulation of the T-cell response .
Cat. No.: HY-P810967
Synonyms: ATP6IP2, CAPER, ELDF10, HT028, MSTP009, PSEC0072, ATP6AP2, Renin receptor, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H(+)-transporting lysosomal-interacting protein 2, ER-localized type I transmembrane adapter, Embryonic liver differentiation factor 10, N14F, Renin/prorenin receptor, Vacuolar ATP synthase membrane sector-associated protein M8-9, ATP6M8-9, V-ATPase M8.9 subunit
Cat. No.: HY-P72099
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ATP6AP2; ER-Localized Type I Transmembrane Adapter; Prev. ATP6IP2; Prorenin Receptor; Renin Receptor; ELDF10; ATP6M8-9; N14F; ATPase H(+)-Transporting Lysosomal-Interacting Protein 2; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump) Membrane Sect
Species:
Human
Source:
E. coli
Cat. No.: HY-P72100
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ATP6AP2; ER-Localized Type I Transmembrane Adapter; Prev. ATP6IP2; Prorenin Receptor; Renin Receptor; ELDF10; ATP6M8-9; N14F; ATPase H(+)-Transporting Lysosomal-Interacting Protein 2; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump) Membrane Sect
Species:
Human
Source:
E. coli
Cat. No.: HY-P75598
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CADM1; Immunoglobulin Superfamily Member 4; Prev. TSLC1; Nectin-Like 2; Prev. IGSF4; TSLC-1; IGSF4A; Immunoglobulin Superfamily, Member 4; SYNCAM; TSLC1/Nectin-Like 2/IGSF4; NECL2; Truncated CADM1 Protein; Tumor Suppressor In Lung Cancer 1; CADM1 Protein
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
