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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
MAGE
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "MAGE" in MCE Product Catalog:
Target:
Research Areas:
JW480 is a selective KIAA1363/AADACL1 inhibitor with oral activity, featuring IC50 values of 12 nM against human KIAA1363, 20 nM against mouse KIAA1363. JW480 blocks lipid deacetylase activity to restrain HAG metabolism and lowers retinyl ester hydrolase function in hepatic stellate cells. JW480 reduces MAGE lipid levels and inhibits migration, invasion, survival and tumor growth of prostate cancer cells. JW480 lowers PKCδ phosphorylation, facilitates HAGP accumulation, diminishes platelet aggregation, dense granule secretion and Ca 2+ flux, delays arterial thrombosis and prolongs tail bleeding time in rats. JW480 can be used for the study of prostate cancer and thrombosis .
Cat. No.: HY-169087
CAS No.: 3057446-77-9
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MJBIA9836 is a MAGE-A3 ligand with a Kd of approximately 8.1 μM. MJBIA9836 elevates MAGE-A3 levels in MAGE-A3-positive cells. MJBIA9836 serves as a Ligand for Target Protein for PROTAC for the synthesis of MAGE-A3 PROTAC degraders, such as KL-465 (HY-169086). MJBIA9836 can be used in the research of MAGE-A3-positive cancers .
Cat. No.: HY-169086
CAS No.: 3057446-82-6
KL-465 is a MAGE-A3 PROTAC degrader that degrades MAGE-A3 in HeLa cells with a DC50 of 2 μM. KL-465 inhibits the proliferation of MAGE-A3-positive cancer cells. KL-465 can be used for the research of MAGE-A3-related cancers .
Cat. No.: HY-P3640
CAS No.: 178243-46-4
Cat. No.: HY-P10491
CAS No.: 252875-61-9
Cat. No.: HY-P10263
CAS No.: 144449-86-5
Synonyms: MAGE-1(161-169), human
Cat. No.: HY-P10264
CAS No.: 154652-68-3
Synonyms: MAGE-3(168-176), human
Cat. No.: HY-P2524
CAS No.: 160295-81-8
Cat. No.: HY-149452
CAS No.: 2758867-71-7
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SJ1008066 is a MAGE-A11 inhibitor with anIC50 of 0.13 μM. SJ 1008066 binds to the MAGE homology domain (MHD) and disrupts MAGE-A11:PCF11 interaction .
Cat. No.: HY-P10496A
Cat. No.: HY-P10496
CAS No.: 160213-30-9
Cat. No.: HY-P1842
CAS No.: 171066-85-6
Cat. No.: HY-165025
CAS No.: 112014-15-0
Cat. No.: HY-P990603
Synonyms: RG-6290
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Cat. No.: HY-P11129
CAS No.: 289905-22-2
Cat. No.: HY-P11621A
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Cat. No.: HY-P11621
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
