12 Results for "

Mechanosensitive

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "Mechanosensitive" in MCE Product Catalog:

126
126 Publications Verification
Cat. No.: HY-P1410
CAS No.: 1209500-46-8
GsMTx4 is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
loading...
    loading...
126
126 Publications Verification
Cat. No.: HY-P1410A
GsMTx4 TFA is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 TFA is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology .
loading...
    loading...
49
49 Cited Publications
Cat. No.: HY-B1906
CAS No.: 57-92-1
Synonyms: Agrept; Agrimycin; Streptomycin A
Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P1410B
D-GsMTx4 is a spider peptide and the D enantiomer of GsMTx4 (HY-P1410). D-GsMTx4 inhibits the mechanosensitive ion channel Piezo2. D-GsMTx4 inhibits [Ca 2+]i elevation. D-GsMTx4 inhibits mTOR and PI3K-Akt signaling pathways. D-GsMTx4 inhibits mechanical allodynia and thermal hyperalgesia. D-GsMTx4 can be used in researches of mechanical stress, chronic pain and idiopathic pulmonary fibrosis .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P1410C
D-GsMTx4 TFA is a spider peptide and the D enantiomer of GsMTx4 (HY-P1410). D-GsMTx4 TFA inhibits the mechanosensitive ion channel Piezo2. D-GsMTx4 TFA inhibits [Ca 2+]i elevation. D-GsMTx4 TFA inhibits mTOR and PI3K-Akt signaling pathways. D-GsMTx4 TFA inhibits mechanical allodynia and thermal hyperalgesia. D-GsMTx4 TFA can be used in researches of mechanical stress, chronic pain and idiopathic pulmonary fibrosis .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-131018
CAS No.: 651005-90-2
Purity:  99.93%
Jedi2 is a Piezo1 activator, but not a specific Piezo2 activator. Jedi2 binds to the mouse Piezo1 proteins with a Kd of 2770??μM .
loading...
    loading...
Cat. No.: HY-B1906R
CAS No.: 57-92-1
Synonyms: Agrept (Standard); Agrimycin (Standard); Streptomycin A (Standard)
Streptomycin (Standard) is the analytical standard of Streptomycin. This product is intended for research and analytical applications. Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .
loading...
    loading...
Cat. No.: HY-N15781
CAS No.: 1882060-21-0
Category:  

Lipids

Trans-FAAzo-4 is a photo-switchable fatty acid analogue used in photo-pharmacology. Trans-FAAzo-4 is able to alter membrane lateral pressure and thus control opening and closing of mechanosensitive ion channels .
loading...
    loading...
Cat. No.: HY-107813R
CAS No.: 149022-22-0
Synonyms: BAY 41-6551 sulfate (Standard)
Research Areas:  

Infection Cancer

Streptomycin (Standard) is the analytical standard of Streptomycin. This product is intended for research and analytical applications. Streptomycin (Agrept) is an effective antibiotic against M. tuberculosis, is used for the research of tuberculosis (TB). Streptomycin also is a bacteriocidal agent that can be used for the research of a number of bacterial infections. Streptomycin can bind strongly to nucleic acids, interferes and blocks protein synthesis while permitting continued RNA and DNA synthesis. Streptomycin, as a common antibiotic used in culture media, also is a blocker of stretch-activated and mechanosensitive ion channels in neurons and cardiac myocytes .
loading...
    loading...
Cat. No.: HY-106935A
CAS No.: 113240-27-0
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

CGP 29030A is an orally effective and specific analgesic agent. CGP 29030A inhibits nociceptive spinal cord neurons without affecting normal sensory functions. CGP 29030A also inhibits gamma motor neurons, which may be beneficial for studying pain disorders that occur concurrently due to increased motor activity (such as cramp, spasm) .
loading...
    loading...
Cat. No.: HY-181467
CAS No.: 3081200-39-4
Research Areas:  

Metabolic Disease

KC159 is a Yoda1 analog, as well as an agonist of Piezo1 and Piezo2. KC159 can be used for cultured adipocyte production .
loading...
    loading...
Cat. No.: HY-P86875
Synonyms: DHS Fam38a Family with sequence similarity 38 member A KIAA0233 Membrane protein induced by beta-amyloid treatment Mib PIEZ1_HUMAN Piezo-type Mechanosensitive ion channel component 1 PIEZO1 Protein FAM38A DHS Fam38a Family with sequence similarity 38 member A KIAA0233 Membrane protein induced by beta-amyloid treatment Mib PIEZ1_HUMAN Piezo-type Mechanosensitive ion channel component 1 PIEZO1 Protein FAM38A Protein FAM38B Protein PIEZO1

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
  • 1