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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
NF1
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "NF1" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P704205
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: YBX1; Y-Box Binding Protein 1; NSEP1; YB-1; DBPB; YB1; MDR-NF1; NSEP-1; CSDA2; BP-8; CSDB; CCAAT-Binding Transcription Factor I Subunit A; Nuclease-Sensitive Element-Binding Protein 1; Enhancer Factor I Subunit A; Y-Box Transcription Factor; Y-Box-Binding
Species:
Human
Source:
E. coli
Target:
Research Areas:
NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway. NST-628 inhibits RAS- and RAF-driven cancers and demonstrated potent inhibition in mutant KRAS, NRAS, BRAF class II/III, and NF1-mutant tumors [1].
Cat. No.: HY-W273690
CAS No.: 1028-33-7
Synonyms: 1-Hexyltheobromine; Hexyltheobromine
Target:
Research Areas:
Pentifylline (1-Hexyltheobromine; Hexyltheobromine), PTX (HY-B0715) precursor compound, is a vasodilator. Pentifylline decreases procollagen levels and inhibits collagen production. Pentifylline reduces functional nuclear NF-1 to suppress procollagen gene transcription [1] .
Cat. No.: HY-RS17398
Target:
Research Areas:
Nf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09233
Target:
Research Areas:
NF1 Human Pre-designed siRNA Set A contains three designed siRNAs for NF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23853
Target:
Research Areas:
Nf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Nf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-156872
CAS No.: 1952236-19-9
MTX-216 is a dual ATP-competitive inhibitor of PI3K and EGFR. MTX-216 cosuppresses Ki-67 and ribosomal S6 phosphorylation and induces apoptosis in NF1 LOF cells. MTX-216 suppresses the activity of SYK kinase, with an IC50 of 281 nM. MTX-216 is used in the research of Melanoma [1].
Cat. No.: HY-187882
CAS No.: 3079099-31-0
Synonyms: PAS-004
Nuvrumetinib (PAS-004) is a macrocyclic MEK inhibitor. Nuvrumetinib functionally inhibits MEK1/2, thereby suppressing pERK in tumors. Nuvrumetinib inhibits the proliferation of NRAS-mutant cancer cells. Nuvrumetinib can be used in studies related to NRAS G12C-mutant solid tumors, neurofibromatosis type 1 (NF1), RASopathies and laminopathies .
Cat. No.: HY-P85511
Synonyms: 1110019L22Rik; 1500041O16Rik; AA589446; AI746521; CAAT box transcription factor; CCAAT binding transcription factor; CCAAT box binding transcription factor; CCAAT-box-binding transcription factor; CNFI C; CTF; CTF5; MGC137374; MGC20153; NF I; NF I/C; NF-I/C; NF1 C; NF1-C; NF1C; NFI; NFI-C; NFI/C; NFIC; NFIC_HUMAN; Nuclear factor 1; Nuclear factor 1 C type; Nuclear factor 1 C-type; Nuclear factor 1/C; Nuclear factor I/C; TGGCA binding protein; TGGCA-binding protein; Transcription factor NFIC.
Cat. No.: HY-P702822
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: YBX1; Y-Box Binding Protein 1; NSEP1; YB-1; DBPB; YB1; MDR-NF1; NSEP-1; CSDA2; BP-8; CSDB; CCAAT-Binding Transcription Factor I Subunit A; Nuclease-Sensitive Element-Binding Protein 1; Enhancer Factor I Subunit A; Y-Box Transcription Factor; Y-Box-Binding Protein 1; DNA-
Species:
Mouse
Source:
P. pastoris
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
