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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
NOS cofactor
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "NOS cofactor" in MCE Product Catalog:
Synonyms: (Rac)-Sapropterin
Category:
Alkaloids Other Alkaloids Disease markers Endogenous metabolite Disease Research Fields Inflammation/Immunology Cardiovascular System Disorder
Target:
Cat. No.: HY-W071685
CAS No.: 945-43-7
Target:
Research Areas:
6, 7-dimethyl-5,6,7, 8-Tetrahydropterin hydrochloride is a synthetic analogue of tetrahydro-L-bioterin and is used as a cofactor required for the NOS isoforms, phenylalanine, tyrosine and tryptophan hydroxylases, and other enzymes .
Cat. No.: HY-186391
CAS No.: 91901-11-0
Target:
Research Areas:
AGMO-IN-1 is an alkylglycerol monooxygenase (AGMO) inhibitor. AGMO-IN-1 competitively binds with BH4 at the cofactor-binding site of BH4-dependent AGMO, inhibiting AGMO activity (rat IC50 = 26-100 µM); AGMO-IN-1 shows weaker inhibitory activity against PAH and NOS than against AGMO. AGMO-IN-1 inhibits preadipocyte differentiation, reduces lipid droplet accumulation in adipocytes and hepatocytes, blocks IL-4-induced M2-like polarization of macrophages, and slows cell cycle progression during the mitotic clonal expansion phase, making it useful for research related to nonalcoholic hepatic steatosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
