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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Nuclear localizing sequence
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Nuclear localizing sequence" in MCE Product Catalog:
Cat. No.: HY-P11744
CAS No.: 503474-42-8
Cat. No.: HY-P4076
CAS No.: 791642-10-9
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Cat. No.: HY-P11208C
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Cat. No.: HY-P11208
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Cat. No.: HY-174499
Cas9 Nickase D10A mRNA expresses a version of the Streptococcus pyogenes SF370 Cas9 protein (CRISPR Associated Protein 9) that contains a D10A amino acid substitution. This mRNA also contains a C-terminal nuclear localization signal followed by a HA tag.Cas9 functions as part of the CRISPR (clustered regularly interspaced short palindromic repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform the DNA cleavage. While wild-type Cas9 creates a double-stranded break at the target site, Cas9 nickase creates a single-stranded break. This favors homology-directed repair and decreases the occurrence of non-homologous end joining.
Cat. No.: HY-P11231
CAS No.: 2780353-11-7
Synonyms: FUS(364-369)-TAT
Cat. No.: HY-P11948
CAS No.: 253328-16-4
Cat. No.: HY-P11948A
Cat. No.: HY-174791
The Cre-T2A-GFP mRNA is a capped and polyadenylated messenger RNA encoding a Cre recombinase with a nuclear localization sequence (NLS) and a green fluorescent protein (GFP). The incorporation of N1-Methylpseudo-UTP can reduce the immunogenicity of the resulting mRNA.
Cat. No.: HY-P11662
CAS No.: 521076-75-5
Cat. No.: HY-187486A
Synonyms: DOPE-PEG2000-Mal-Cys-MPG
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DOPE-PEG2000-MPG (DOPE-PEG2000-Mal-Cys-MPG) is an amphiphilic lipid-PEG-peptide conjugate consisting of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the MPG peptide, a cell-penetrating peptide derived from the HIV-1 gp41 fusion peptide and the nuclear localization sequence (NLS) of SV40 large T antigen. DOPE-PEG2000-MPG is used for intracellular delivery of siRNA, DNA, and other macromolecules.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
