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Nuclear localizing sequence is a peptide sequence that functions as an inducer and exhibits membrane permeability in mammalian cells. Nuclear localizing sequence enhances cellular uptake and directs conjugated ruthenium (II) complexes to the nucleus for nuclear DNA imaging.

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Nuclear localizing sequence

Nuclear localizing sequence 화학구조

CAS No. : 503474-42-8

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Nuclear localizing sequence Related Antibodies

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제품 설명

Nuclear localizing sequence is a peptide sequence that functions as an inducer and exhibits membrane permeability in mammalian cells. Nuclear localizing sequence enhances cellular uptake and directs conjugated ruthenium (II) complexes to the nucleus for nuclear DNA imaging[1][2].

In Vitro

The nuclear localizing sequence (Compound 12a) targets the conjugated [Ru (bpy)2 (dppz)]2+ complex to the cell nucleus, and enables selective imaging of nuclear DNA by virtue of the "light-switch" emission behavior of this complex[1].
Conjugation of the nuclear localizing sequence with a ruthenium (II) biquinoline complex bearing perchlorate counterions enables efficient cellular uptake in CHO and HeLa cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Nuclear localizing sequence Related Antibodies
분자량

1282.60

화학식

C55H103N21O12S
CAS No.
Sequence

Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro-NH2
Sequence Shortening

VQRKRQKLMP-NH2
선적

Room temperature in continental US; may vary elsewhere.
보관

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순도&문서
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Nuclear localizing sequence Related Classifications

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Keywords:

Nuclear localizing sequence503474-42-8Otherspeptidecell nucleusInhibitorinhibitorinhibit

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Nuclear localizing sequence
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HY-P11744
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