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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
OPA1
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "OPA1" in MCE Product Catalog:
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6 Publications Verification
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AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H2S) donor. AP39 increases intracellular H2S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research [1] .
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1 Cited Publications
Cat. No.: HY-158162
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SIRT3 activator 1 (Compound 5v) is a SIRT3 activator. SIRT3 activator 1 selectively elevates SIRT3 expression, leading to the upregulation of SOD2 and OPA1 expression, effectively preventing mitochondrial dysfunction, mitigating oxidative stress, and preserving cardiomyocyte viability. SIRT3 activator 1 can be used for research of cardiovascular diseases [1].
Cat. No.: HY-RS09789
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OPA1 Human Pre-designed siRNA Set A contains three designed siRNAs for OPA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16968
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Opa1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Opa1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Synonyms: 3'-Azido-3'-deoxythymidine-5'-triphosphate tetraammonium
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AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) tetraammonium is an active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate tetraammonium exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate tetraammonium also inhibits the DNA polymerase of HBV. AZT triphosphate tetraammonium activates the mitochondria-mediated apoptosis pathway [1] .
Cat. No.: HY-177306
Opitor-0 is a OPA1 GTPase inhibitor with an IC50 of 3.0 μM. Opitor-0 disrupts mitochondrial cristae structure and respiratory efficiency, induces mitochondrial fragmentation, enhances cBID-mediated cytochrome c release, and restores the sensitivity of triple-negative breast cancer (TNBC) cells to ABT-737 (HY-50907). Opitor-0 selectively reduces the migration and proliferation capacities of metastatic breast cancer cells, and induces cell death and apoptosis. Opitor-0 can be used in studies related to metastatic breast cancer and triple-negative breast cancer [1] .
Cat. No.: HY-RS23411
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Opa1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Opa1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-116364
CAS No.: 92586-35-1
Synonyms: 3'-Azido-3'-deoxythymidine-5'-triphosphate
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AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate also inhibits the DNA polymerase of HBV. AZT triphosphate activates the mitochondria-mediated apoptosis pathway [1] .
Cat. No.: HY-116364A
Synonyms: 3'-Azido-3'-deoxythymidine-5'-triphosphate TEA
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AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) TEA is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TEA exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate TEA also inhibits the DNA polymerase of HBV. AZT triphosphate TEA activates the mitochondria-mediated apoptosis pathway [1] .
Cat. No.: HY-180786
CAS No.: 3085711-53-8
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DdBIC is a pyroptosis inducer. DdBIC binds to Nur77 and triggers its translocation to mitochondria, activates SDHA to deplete succinyl-CoA, disrupts heme homeostasis, induces electron leakage, and elicits mitochondrial ROS production. DdBIC induces mitochondrial ROS that oxidatively activates OMA1, promotes OPA1 cleavage and its release into the cytoplasm, activates the integrated stress response via PERK, and ultimately activates granzyme B to cleave GSDMC. DdBIC can be used for the study of melanoma [1].
Cat. No.: HY-RS18290
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Med12 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Med12 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08281
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MED12 Human Pre-designed siRNA Set A contains three designed siRNAs for MED12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P86998
Synonyms: Dynamin like 120 kDa protein antibody; Dynamin like 120 kDa protein, mitochondrial antibody; Dynamin-like 120 kDa protein, form S1 antibody; FLJ12460 antibody; Juvenile kjer type optic atrophy antibody; KIAA0567 antibody; KJER type antibody; Large GTP binding protein antibody; largeG antibody; MGM1 antibody; Dynamin like 120 kDa protein antibody; Dynamin like 120 kDa protein, mitochondrial antibody; Dynamin-like 120 kDa protein, form S1 antibody; FLJ12460 antibody; Juvenile kjer type optic atrophy antibody; KIAA0567 antibody; KJER type antibody; Large GTP binding protein antibody; largeG antibody; MGM1 antibody; Mitochondrial dynamin like 120 kDa protein antibody; Mitochondrial dynamin like GTPase antibody; NPG antibody; NTG antibody; OAK antibody; OPA 1 antibody; OPA1 antibody; OPA1 gene antibody; OPA1_HUMAN antibody; Optic atrophy 1 (autosomal dominant) antibody; OPTIC ATROPHY 1 antibody; Optic atrophy 1 gene protein antibody; Optic atrophy 1 homolog (human) antibody; Optic atrophy protein 1 antibody; Optic atrophy protein 1 homolog antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
