Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
OPA1
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "OPA1" in MCE Product Catalog:
2
1
1 Cited Publications
Cat. No.: HY-158162
Target:
Research Areas:
SIRT3 activator 1 (Compound 5v) is a SIRT3 activator. SIRT3 activator 1 selectively elevates SIRT3 expression, leading to the upregulation of SOD2 and OPA1 expression, effectively preventing mitochondrial dysfunction, mitigating oxidative stress, and preserving cardiomyocyte viability. SIRT3 activator 1 can be used for research of cardiovascular diseases [1].
Cat. No.: HY-RS09789
Target:
Research Areas:
OPA1 Human Pre-designed siRNA Set A contains three designed siRNAs for OPA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16968
Target:
Research Areas:
Opa1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Opa1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23411
Target:
Research Areas:
Opa1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Opa1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-177306
Opitor-0 is a OPA1 GTPase inhibitor with an IC50 of 3.0 μM. Opitor-0 disrupts mitochondrial cristae structure and respiratory efficiency, induces mitochondrial fragmentation, enhances cBID-mediated cytochrome c release, and restores the sensitivity of triple-negative breast cancer (TNBC) cells to ABT-737 (HY-50907). Opitor-0 selectively reduces the migration and proliferation capacities of metastatic breast cancer cells, and induces cell death and apoptosis. Opitor-0 can be used in studies related to metastatic breast cancer and triple-negative breast cancer [1] .
Cat. No.: HY-P706216
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Dynamin-like GTPase OPA1, mitochondrial; Optic atrophy protein 1; Dynamin-like GTPase OPA1; OPA1; KIAA0567
Species:
Human
Source:
CHO
Cat. No.: HY-185936
CAS No.: 3119104-72-9
Zulaporsen rocopertide can promote the synthesis of optic atrophy 1 (OPA1) protein.
Cat. No.: HY-180786
CAS No.: 3085711-53-8
Research Areas:
DdBIC is a pyroptosis inducer. DdBIC binds to Nur77 and triggers its translocation to mitochondria, activates SDHA to deplete succinyl-CoA, disrupts heme homeostasis, induces electron leakage, and elicits mitochondrial ROS production. DdBIC induces mitochondrial ROS that oxidatively activates OMA1, promotes OPA1 cleavage and its release into the cytoplasm, activates the integrated stress response via PERK, and ultimately activates granzyme B to cleave GSDMC. DdBIC can be used for the study of melanoma [1].
Cat. No.: HY-RS18290
Target:
Research Areas:
Med12 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Med12 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08281
Target:
Research Areas:
MED12 Human Pre-designed siRNA Set A contains three designed siRNAs for MED12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P86998
Synonyms: Dynamin like 120 kDa protein antibody; Dynamin like 120 kDa protein, mitochondrial antibody; Dynamin-like 120 kDa protein, form S1 antibody; FLJ12460 antibody; Juvenile kjer type optic atrophy antibody; KIAA0567 antibody; KJER type antibody; Large GTP binding protein antibody; largeG antibody; MGM1 antibody; Dynamin like 120 kDa protein antibody; Dynamin like 120 kDa protein, mitochondrial antibody; Dynamin-like 120 kDa protein, form S1 antibody; FLJ12460 antibody; Juvenile kjer type optic atrophy antibody; KIAA0567 antibody; KJER type antibody; Large GTP binding protein antibody; largeG antibody; MGM1 antibody; Mitochondrial dynamin like 120 kDa protein antibody; Mitochondrial dynamin like GTPase antibody; NPG antibody; NTG antibody; OAK antibody; OPA 1 antibody; OPA1 antibody; OPA1 gene antibody; OPA1_HUMAN antibody; Optic atrophy 1 (autosomal dominant) antibody; OPTIC ATROPHY 1 antibody; Optic atrophy 1 gene protein antibody; Optic atrophy 1 homolog (human) antibody; Optic atrophy protein 1 antibody; Optic atrophy protein 1 homolog antibody;
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
